Lack of improvement of oral absorption of ME3277 by prodrug formation is ascribed to the intestinal efflux mediated by breast cancer resistant protein (BCRP/ABCG2). (Q40431648)

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English	Lack of improvement of oral absorption of ME3277 by prodrug formation is ascribed to the intestinal efflux mediated by breast cancer resistant protein (BCRP/ABCG2).	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Lack of improvement of oral absorption of ME3277 by prodrug formation is ascribed to the intestinal efflux mediated by breast cancer resistant protein (BCRP/ABCG2). (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Johan W. Jonker

9

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author name string

Chihiro Kondo

1

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Reiko Onuki

2

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Hiroyuki Kusuhara

3

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Hiroshi Suzuki

4

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Michiko Suzuki

5

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Noriko Okudaira

6

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Maho Kojima

7

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Kazuya Ishiwata

8

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Yuichi Sugiyama

10

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

publication date

7 April 2005

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Europe PubMed Central

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20 September 2017

Pharmaceutical Research

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Europe PubMed Central

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20 September 2017

22

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Europe PubMed Central

PubMed publication ID

20 September 2017

4

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Europe PubMed Central

PubMed publication ID

20 September 2017

613-618

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Europe PubMed Central

PubMed publication ID

20 September 2017

Functional analysis of SNPs variants of BCRP/ABCG2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15846469

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Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15846469

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Transporter-Enzyme Interactions: Implications for Predicting Drug-Drug Interactions from In Vitro Data

1 reference

https://pubmed.ncbi.nlm.nih.gov/15846469

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ABCG2 transports sulfated conjugates of steroids and xenobiotics

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https://pubmed.ncbi.nlm.nih.gov/15846469

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Influence of anesthetic regimens on intestinal absorption in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15846469

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Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)

1 reference

https://pubmed.ncbi.nlm.nih.gov/15846469

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Intestinal MDR transport proteins and P-450 enzymes as barriers to oral drug delivery

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Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan

1 reference

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Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

1 reference

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based on heuristic

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A study of the intestinal absorption of an ester-type prodrug, ME3229, in rats: active efflux transport as a cause of poor bioavailability of the active drug

1 reference

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The mammalian carboxylesterases: from molecules to functions

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The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.

1 reference

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Measurement of intestinal absorption in mice by a double-label radioisotope perfusion technic

1 reference

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Role of metabolic enzymes and efflux transporters in the absorption of drugs from the small intestine

1 reference

https://pubmed.ncbi.nlm.nih.gov/15846469

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based on heuristic

inferred from PubMed ID database lookup

Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15846469

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Impaired renal excretion of 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole (E3040) sulfate in breast cancer resistance protein (BCRP1/ABCG2) knockout mice

1 reference

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The breast cancer resistance protein (Bcrp1/Abcg2) restricts exposure to the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

1 reference

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Quantitative evaluation of the function of small intestinal P-glycoprotein: comparative studies between in situ and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/15846469

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based on heuristic

inferred from PubMed ID database lookup

Polarized efflux of mono- and diacid metabolites of ME3229, an ester-type prodrug of a glycoprotein IIb/IIIa receptor antagonist, in rat small intestine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15846469

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11095-005-2487-9

1 reference

https://api.fatcat.wiki/v0/release/ailbdtjtjfcgrmwvm7nis2nn5y

30 July 2022

based on heuristic

mapped directly with Wikidata item

release_ailbdtjtjfcgrmwvm7nis2nn5y

1 reference

https://api.fatcat.wiki/v0/release/ailbdtjtjfcgrmwvm7nis2nn5y

30 July 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

https://api.fatcat.wiki/v0/release/ailbdtjtjfcgrmwvm7nis2nn5y

30 July 2022

based on heuristic

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