Cdc25B cooperates with Cdc25A to induce mitosis but has a unique role in activating cyclin B1-Cdk1 at the centrosome. (Q40363369)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16216921%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Cdc25B cooperates with Cdc25A to induce mitosis but has a unique role in activating cyclin B1-Cdk1 at the centrosome (English)

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7 January 2020

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7 January 2020

Helena Källström

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7 January 2020

Andreas Lundgren

series ordinal

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7 January 2020

Emad Barsoum

series ordinal

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7 January 2020

Christina Karlsson Rosenthal

series ordinal

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7 January 2020

language of work or name

English

0 references

publication date

1 October 2005

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7 January 2020

published in

Journal of Cell Biology

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7 January 2020

volume

171

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7 January 2020

issue

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7 January 2020

page(s)

35-45

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Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases

7 January 2020

cites work

1 reference

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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Dual phosphorylation controls Cdc25 phosphatases and mitotic entry

22 September 2017

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Active cyclin B1-Cdk1 first appears on centrosomes in prophase

22 September 2017

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Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability

22 September 2017

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Dual mode of degradation of Cdc25 A phosphatase

22 September 2017

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Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation

22 September 2017

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Cyclin A- and cyclin E-Cdk complexes shuttle between the nucleus and the cytoplasm

22 September 2017

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Regulation of cyclin-Cdk activity in mammalian cells

22 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171226

Absence of apparent phenotype in mice lacking Cdc25C protein phosphatase

22 September 2017

1 reference

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Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint

22 September 2017

1 reference

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Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase

22 September 2017

1 reference

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Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis

22 September 2017

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Specificity of natural and artificial substrates for human Cdc25A.

22 September 2017

1 reference

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Cdc25B and Cdc25C differ markedly in their properties as initiators of mitosis

22 September 2017

1 reference

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Cytoplasmic localization of human cdc25C during interphase requires an intact 14-3-3 binding site

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171226

Phosphorylation and activation of human cdc25-C by cdc2--cyclin B and its involvement in the self-amplification of MPF at mitosis

22 September 2017

1 reference

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Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase

22 September 2017

1 reference

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Cdc25A is a novel phosphatase functioning early in the cell cycle

22 September 2017

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Activation of p34cdc2 protein kinase by microinjection of human cdc25C into mammalian cells. Requirement for prior phosphorylation of cdc25C by p34cdc2 on sites phosphorylated at mitosis

22 September 2017

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Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog

22 September 2017

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Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2

22 September 2017

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Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2

22 September 2017

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Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B.

22 September 2017

1 reference

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p55CDC25 is a nuclear protein required for the initiation of mitosis in human cells.

22 September 2017

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Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport

22 September 2017

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cdc25 is a nuclear protein expressed constitutively throughout the cell cycle in nontransformed mammalian cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171226

Cyclin A is required at two points in the human cell cycle

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171226

Identification of essential genes in cultured mammalian cells using small interfering RNAs.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171226

Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171226

Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171226

The cdc25B phosphatase is essential for the G2/M phase transition in human cells

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171226

The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171226

cdc25+ functions as an inducer in the mitotic control of fission yeast

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171226

Cdc25A localisation and shuttling: characterisation of sequences mediating nuclear export and import.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171226

Characterisation of Cdc25B localisation and nuclear export during the cell cycle and in response to stress

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171226

Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition.

20 August 2018

1 reference

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Cdk2-dependent phosphorylation of the NF-Y transcription factor is essential for the expression of the cell cycle-regulatory genes and cell cycle G1/S and G2/M transitions

20 August 2018

1 reference

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Cdk2-dependent phosphorylation of the NF-Y transcription factor and its involvement in the p53-p21 signaling pathway

20 August 2018

1 reference

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Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding.

20 August 2018

1 reference

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Cdc25A stability is controlled by the ubiquitin-proteasome pathway during cell cycle progression and terminal differentiation.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171226

Human cyclin A is required for mitosis until mid prophase

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171226

Centrosomal and cytoplasmic Cdc2/cyclin B1 activation precedes nuclear mitotic events

20 August 2018

1 reference

12 December 2020

Cytoplasmic accumulation of cdc25B phosphatase in mitosis triggers centrosomal microtubule nucleation in HeLa cells

1 reference

12 December 2020

Ultraviolet light-induced G2 phase cell cycle checkpoint blocks cdc25-dependent progression into mitosis

1 reference

12 December 2020

Hyperphosphorylation of the N-terminal Domain of Cdc25 Regulates Activity toward Cyclin B1/Cdc2 But Not Cyclin A/Cdk2

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200503066

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16216921%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16216921%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

16216921

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16216921%20AND%20SRC:MED&resulttype=core&format=json