Depletion of CLL-associated patrolling monocytes and macrophages controls disease development and repairs immune dysfunction in vivo (Q40369611)

19 September 2017

title

Depletion of CLL-associated patrolling monocytes and macrophages controls disease development and repairs immune dysfunction in vivo (English)

1 reference

19 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26522085%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26522085%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

B S Hanna

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26522085%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

F McClanahan

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6 June 2020

H Yazdanparast

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6 June 2020

V Kalter

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6 June 2020

P M Rößner

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6 June 2020

A Benner

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6 June 2020

C Dürr

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6 June 2020

J G Gribben

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6 June 2020

P Lichter

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6 June 2020

M Seiffert

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6 June 2020

publication date

2 November 2015

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19 September 2017

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6 June 2020

volume

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6 June 2020

issue

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6 June 2020

page(s)

570-579

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From pathogenesis to treatment of chronic lymphocytic leukaemia

6 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

The microenvironment in mature B-cell malignancies: a target for new treatment strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Soluble CD14 is a novel monocyte-derived survival factor for chronic lymphocytic leukemia cells, which is induced by CLL cells in vitro and present at abnormally high levels in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Inflammatory cytokines and signaling pathways are associated with survival of primary chronic lymphocytic leukemia cells in vitro: a dominant role of CCL2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Nr4a1-dependent Ly6C(low) monocytes monitor endothelial cells and orchestrate their disposal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Monocyte recruitment during infection and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Monocytes and macrophages in cancer: development and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

The cellular and molecular origin of tumor-associated macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Coordinated regulation of myeloid cells by tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Understanding the immunodeficiency in chronic lymphocytic leukemia: potential clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

PD-L1 checkpoint blockade prevents immune dysfunction and leukemia development in a mouse model of chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Association of an increased frequency of CD14+ HLA-DR lo/neg monocytes with decreased time to progression in chronic lymphocytic leukaemia (CLL).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

CLL-cells induce IDOhi CD14+HLA-DRlo myeloid-derived suppressor cells that inhibit T-cell responses and promote TRegs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

The lymph node microenvironment promotes B-cell receptor signaling, NF-κB activation, and tumor proliferation in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Development of CLL in the TCL1 transgenic mouse model is associated with severe skewing of the T-cell compartment homologous to human CLL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

E(mu)-TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Local apoptosis mediates clearance of macrophages from resolving inflammation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Two physically, functionally, and developmentally distinct peritoneal macrophage subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Macrophage plasticity and polarization: in vivo veritas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Identification of splenic reservoir monocytes and their deployment to inflammatory sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Soluble domain 1 of platelet-endothelial cell adhesion molecule (PECAM) is sufficient to block transendothelial migration in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Migration of monocytes across endothelium and passage through extracellular matrix involve separate molecular domains of PECAM-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Emu-TCL1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

High-level expression of the T-cell chemokines CCL3 and CCL4 by chronic lymphocytic leukemia B cells in nurselike cell cocultures and after BCR stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Chemokines and chemokine receptors: positioning cells for host defense and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Lenalidomide inhibits lymphangiogenesis in preclinical models of mantle cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Autoantigen can promote progression to a more aggressive TCL1 leukemia by selecting variants with enhanced B-cell receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

The monocytic population in chronic lymphocytic leukemia shows altered composition and deregulation of genes involved in phagocytosis and inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Extracellular HMGB1 promotes differentiation of nurse-like cells in chronic lymphocytic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Ly-1 B-cell clones similar to human chronic lymphocytic leukemias routinely develop in older normal mice and young autoimmune (New Zealand Black-related) animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Ovarian cancer progression is controlled by phenotypic changes in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Cytokine-driven loss of plasmacytoid dendritic cell function in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Anti-inflammatory properties of the novel antitumor agent yondelis (trabectedin): inhibition of macrophage differentiation and cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Macrophage IL-10 blocks CD8+ T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.305

IGHV unmutated CLL B cells are more prone to spontaneous apoptosis and subject to environmental prosurvival signals than mutated CLL B cells

21 January 2018

1 reference

12 December 2020

Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug

1 reference

12 December 2020

Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes

1 reference

12 December 2020

Dendritic cells infiltrating human non-small cell lung cancer are blocked at immature stage

1 reference

12 December 2020

Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1.

1 reference

12 December 2020

CD4+ T cells, but not non-classical monocytes, are dispensable for the development of chronic lymphocytic leukemia in the TCL1-tg murine model.

1 reference

12 December 2020

Intercellular adhesion molecular 1 on monocytes mediates adhesion as well as trans-endothelial migration and can be downregulated using antisense oligonucleotides

1 reference

12 December 2020

Functional dissection of the chromosome 13q14 tumor-suppressor locus using transgenic mouse lines

1 reference

12 December 2020

Genomic and phenotypic characterization of nurse-like cells that promote drug resistance in chronic lymphocytic leukemia

1 reference

12 December 2020

Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses

1 reference

12 December 2020