The PI3K inhibitor LY294002 blocks drug export from resistant colon carcinoma cells overexpressing MRP1. (Q40351356)

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9 January 2020

title

The PI3K inhibitor LY294002 blocks drug export from resistant colon carcinoma cells overexpressing MRP1 (English)

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9 January 2020

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9 January 2020

R Abdul-Ghani

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9 January 2020

K Jürchott

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9 January 2020

A Solf

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9 January 2020

M Dietel

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9 January 2020

R Schäfer

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language of work or name

English

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publication date

1 March 2006

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volume

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issue

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9 January 2020

page(s)

1743-1752

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Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: A comparison with tyrosine kinase and protein kinase C inhibition

9 January 2020

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WiDr is a derivative of another colon adenocarcinoma cell line, HT-29.

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Chk1 in the DNA damage response: conserved roles from yeasts to mammals

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Regulation of [Ca2+ ]i homeostasis in MRP1 overexpressing cells

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The leukotriene LTD4 receptor antagonist MK571 specifically modulates MRP associated multidrug resistance

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Hyperphosphorylation of tau is mediated by ERK activation during anticancer drug-induced apoptosis in neuroblastoma cells.

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Roles of the PI-3K and MEK pathways in Ras-mediated chemoresistance in breast cancer cells.

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Role and regulation of activation of caspases in cisplatin-induced injury to renal tubular epithelial cells

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HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells.

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Differential expression of sphingolipids in MRP1 overexpressing HT29 cells

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Phosphatidylinositol 3'-kinase activation leads to multidrug resistance protein-1 expression and subsequent chemoresistance in advanced prostate cancer cells.

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Differential effect of vinorelbine versus paclitaxel on ERK2 kinase activity during apoptosis in MCF-7 cells

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Mechanism of apoptosis induced by doxorubicin through the generation of hydrogen peroxide.

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Topotecan inhibits VEGF- and bFGF-induced vascular endothelial cell migration via downregulation of the PI3K-Akt signaling pathway

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Inhibition of phosphorylase kinase, and tyrosine protein kinase activities by quercetin.

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7 January 2021

Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells

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7 January 2021

Development of multidrug-resistance convertors: sense or nonsense?

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7 January 2021

Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine

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7 January 2021

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Identifiers

DOI

10.1038/SJ.ONC.1209201

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Dimensions Publication ID

9 January 2020

1008371829

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