Drug metabolism by the human fetus (Q40287711)

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scientific article published on July 1980

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English	Drug metabolism by the human fetus	scientific article published on July 1980

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instance of

scholarly article

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stated in

Europe PubMed Central

PubMed publication ID

6994979

retrieved

19 September 2017

review article

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Europe PubMed Central

title

Drug metabolism by the human fetus (English)

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Europe PubMed Central

PubMed publication ID

6994979

retrieved

19 September 2017

author name string

M R Juchau

series ordinal

1

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stated in

Europe PubMed Central

PubMed publication ID

6994979

retrieved

19 September 2017

S T Chao

series ordinal

2

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stated in

Europe PubMed Central

PubMed publication ID

6994979

retrieved

19 September 2017

C J Omiecinski

series ordinal

3

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stated in

Europe PubMed Central

PubMed publication ID

6994979

retrieved

19 September 2017

publication date

1 July 1980

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stated in

Europe PubMed Central

PubMed publication ID

6994979

retrieved

19 September 2017

published in

Clinical Pharmacokinetics

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stated in

Europe PubMed Central

PubMed publication ID

6994979

retrieved

19 September 2017

volume

5

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Europe PubMed Central

PubMed publication ID

6994979

retrieved

19 September 2017

issue

4

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Europe PubMed Central

PubMed publication ID

6994979

retrieved

19 September 2017

page(s)

320-339

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Europe PubMed Central

PubMed publication ID

6994979

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19 September 2017

cites work

O-sulfonation of N-hydroxy-2-fluorenylacetamide and 7-hydroxy-N-2-fluorenylacetamide in fetal and placental tissues of humans and guinea pigs

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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inferred from PubMed ID database lookup

Oxidative biotransformation of 2-acetylaminofluorene in fetal and placental tissues of humans and monkeys. Correlations with aryl hydrocarbon hydroxylase activities

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Metabolism of desmethylimipramine in human foetal and adult liver microsomes

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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3,4-Benzpyrene and aniline are hydroxylated by human fetal liver but not by placenta at 6–7 weeks of fetal age

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Drug biotransformation in the human fetus: nitro group reduction

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intra-species variation in chlorpromazine metabolism

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Biotransformation and bioactivation of 7,12-dimethylbenz[a]anthracene in human fetal and placental tissues. Analyses of HPLC profiles and studies with Salmonella typhimurium

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Metabolism of Theophylline to Caffeine in Human Fetal Liver

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Amine oxidase in mice—sex differences and developmental aspects

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Developmental Aspects of Drug Conjugation, with Special Reference to Glucuronidation

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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[Studies on drug demethylation in fetal liver]

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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inferred from PubMed ID database lookup

Human placental hydroxylation of 3,4-benzpyrene during early gestation and at term.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of Chlorpromazine and p‐Nitrobenzoic Acid in the Liver, Intestine and Kidney of the Human Foetus

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Studies on the Metabolism of Steroids in the Foetus. Biosynthesis of Epitestosterone in the Human-Foetal Liver

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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inferred from PubMed ID database lookup

Perinatal development of tertiary amine N-oxidation and NADPH cytochrome C reduction in rat liver microsomes.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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[Studies on the development of glucuronide formation in the liver of newborn; behavior of blood aminophenol glucuronide after administration of acetanilid.]

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Drugs and fetal metabolism

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Catechol-O-methyl transferase: pharmacological aspects and physiological role

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Change in Alcohol Dehydrogenase Isoenzyme Pattern during Development of Human Liver

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Studies on the biotransformation of naphthalene-1,2-oxide in fetal and placental tissues of humans and monkeys

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

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Drug biotransformation in the placenta

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental aspects of the hepatic cytochrome P450 monooxygenase system

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

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Chloramphenicol in the newborn infant. A physiologic explanation of its toxicity when given in excessive doses

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Modulation of monooxygenase activities by hematin and 7,8-benzoflavone in fetal tissues of rats, rabbits, and humans

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Preparation, morphology and drug metabolism of isolated hepatotcyte and liver organ cultures from the human fetus

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Monoamine oxidase activity in the fetal lung and liver

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Differential Inhibition of Aryl Hydrocarbon Hydroxylase in Human Foetal Liver, Adrenal Gland and Placenta*

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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N-acetylprocainamide: an active metabolite of procainamide

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

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Clinical pharmacologic aspects of cytochrome P-450 dependent biotransformation of drugs

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Distribution of enzymes that catalyse reactions of glutathione with alpha beta-unsaturated compounds

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Drug metabolism in the human fetus and newborn infant.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

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Metabolic capabilities of the human fetus: drug biotransformation

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

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Components of the heme biosynthetic pathway and mixed function oxidase activity in human fetal tissues

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

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Drug metabolism in the newborn rabbit

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Dizepam metabolism in human foetal and adult liver

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Drug uptake and catabolism in the fetal period

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Changes in the properties of fetal rat liver during organ culture

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Catechol estrogen formation in placental and fetal tissues of humans, macaques, rats and rabbits

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Induction of drug metabolizing enzyme activities in the human fetus and in the newborn infant

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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The liver microsomal FAD-containing monooxygenase. Spectral characterization and kinetic studies

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

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Active products of fetal drug metabolism.

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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N-demethylation of the carcinogen dimethylnitrosamine by human embryonal tissue (author's transl)

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Esterases in the hearts, lungs and livers of human foetuses before mid-term

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Development of Alcohol Dehydrogenase Activity in the Human Liver

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Biochemical changes of catechol-O-methyltransferase during development of human liver

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

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Acetaminophen: Potentially Toxic Metabolite Formed by Human Fetal and Adult Liver Microsomes and Isolated Fetal Liver Cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Characteristics and differences in the hepatic mixed function oxidase of different species

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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A comparison of the capacity of fetal and adult liver, lung, and brain to convert polycyclic aromatic hydrocarbons to mutagenic and cytotoxic metabolites in mice and rats

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Distribution of some steroid sulphokinases in foetal human tissues

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

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Maternal, fetal, and neonatal metabolism of lidocaine

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

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Drug metabolism by the fetal stump-tailed monkey (Macaca arctoides). Hepatic microsomal N-demethylation and glucuronidation as measured by radiometric assays

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Glucuronide synthesis in foetal liver and other tissues

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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The role of gut flora in the reduction of aromatic nitro-groups

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Benzodiazepine Metabolism in Cultures of Isolated Hepatocytes and Liver Fragments of Human Fetus

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Sulfonamide administration in newborn and premature infants

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Metabolism of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in cultured human fetal aortic smooth muscle cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

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Bilirubin UDP-glucuronyltransferase activity in human fetal liver homogenates

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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The presence of a monooxygenase system in human fetal liver microsomes

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Placental transer and fetal metabolism of diazepam in early human pregnancy

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12 December 2020

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Drug metabolizing systems in homogenates of human immature placentas

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12 December 2020

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Pre- and postnatal enzyme capacity for drug metabolite production

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12 December 2020

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Developmental studies on some enzymes associated with 'detoxication'.

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Analysis of the biotransformation of benzo[a]pyrene in human fetal and placental tissues with high-pressure liquid chromatography

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucuronide synthesis in kidney and gastrointestinal tract

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perinatal development of human blood esterases

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

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Reduced Hepatic Bilirubin Uridine Diphosphate Glucuronyl Transferase and Uridine Diphosphate Glucose Dehydrogenase Activity in the Human Fetus

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

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3,4‐Benzpyrene and N‐Methylaniline Metabolizing Enzymes in the Immature Human Foetus and Placenta*

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

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Aldehyde-oxidizing capacity during development in human and rat liver

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12 December 2020

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UDP-glucuronyltransferase activity towards oestriol in fresh and cultured foetal tissues from man and other species

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Synthesis of p-aminohippuric, hippuric, and salicyluric acids in experimental animals and man

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12 December 2020

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Precocious development of cytochrome P-450 in neonatal rat liver after glucocorticoid treatment

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Drug biotransformation reactions in the human fetal adrenal gland

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12 December 2020

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Formation of carbamazepine epoxide in human fetal liver

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12 December 2020

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The elimination of alcohol in the premature infant

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12 December 2020

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Spectral characteristics of human fetal adrenal microsomes

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12 December 2020

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Bioactivation of procarcinogens to mutagens in human fetal and placental tissues

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reference URL

https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

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Hydroxylation of 3,4-benzpyrene in human fetal tissue homogenates

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6994979

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postnatal development of drug-metabolizing enzyme activity in liver and extrahepatic tissues of swine.

1 reference

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https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

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Coordinated polypeptide synthesis and insertion of protoheme in cytochrome P-450 during development of endoplasmic reticulum membranes

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reference URL

https://pubmed.ncbi.nlm.nih.gov/6994979

retrieved

12 December 2020

based on heuristic

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Fetal and neonatal development of the microsomal monooxygenase system

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6994979

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of ethylmorphine and aniline in human fetal liver

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6994979

retrieved

12 December 2020

based on heuristic

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Formation of 2- and 4-Hydroxyestrogens by Brain, Pituitary, and Liver of the Human Fetus*

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12 December 2020

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Difference in the Substrate Specificities of Drug Metabolizing Enzymes in Human Term Placenta and Fetal Liver

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12 December 2020

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Teratogenic bioactivation of cyclophosphamide

1 reference

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https://pubmed.ncbi.nlm.nih.gov/6994979

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of theophylline to caffeine in premature newborn infants

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/6994979

retrieved

12 December 2020

based on heuristic

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Partial purification and properties of cytochrome P450 from homogenates of human fetal livers

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reference URL

https://pubmed.ncbi.nlm.nih.gov/6994979

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12 December 2020

based on heuristic

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Identifiers

DOI

10.2165/00003088-198005040-00002

1 reference

stated in

Europe PubMed Central

PubMed publication ID

6994979

retrieved

19 September 2017

Dimensions Publication ID

1018115056

0 references

PubMed publication ID

6994979

1 reference

stated in

Europe PubMed Central

PubMed publication ID

6994979

retrieved

19 September 2017

 

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