Characterization of capsid-modified adenovirus vectors containing heterologous peptides in the fiber knob, protein IX, or hexon (Q40226617)

18 September 2017

title

Characterization of capsid-modified adenovirus vectors containing heterologous peptides in the fiber knob, protein IX, or hexon (English)

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18 September 2017

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Kurachi S

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18 September 2017

Koizumi N

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18 September 2017

Sakurai F

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18 September 2017

Kawabata K

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18 September 2017

Sakurai H

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18 September 2017

Nakagawa S

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18 September 2017

Hayakawa T

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18 September 2017

Mizuguchi H

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18 September 2017

publication date

28 September 2006

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18 September 2017

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18 September 2017

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18 September 2017

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18 September 2017

page(s)

266-274

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Adenoviral vectors for gene transfer

18 September 2017

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Modifications of the fiber in adenovirus vectors increase tropism for malignant glioma models

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A simplified system for constructing recombinant adenoviral vectors containing heterologous peptides in the HI loop of their fiber knob

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Generation of fiber-modified adenovirus vectors containing heterologous peptides in both the HI loop and C terminus of the fiber knob

21 January 2018

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Engineering of adenovirus vectors containing heterologous peptide sequences in the C terminus of capsid protein IX.

21 January 2018

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Functional analysis of adenovirus protein IX identifies domains involved in capsid stability, transcriptional activity, and nuclear reorganization

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Fluorescently labeled adenovirus with pIX-EGFP for vector detection

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Use of adenovirus protein IX (pIX) to display large polypeptides on the virion--generation of fluorescent virus through the incorporation of pIX-GFP.

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Genetic incorporation of HSV-1 thymidine kinase into the adenovirus protein IX for functional display on the virion

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Spacers increase the accessibility of peptide ligands linked to the carboxyl terminus of adenovirus minor capsid protein IX

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Neutralizing antibodies to adenovirus serotype 5 vaccine vectors are directed primarily against the adenovirus hexon protein

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Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity

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Identification of sites in adenovirus hexon for foreign peptide incorporation

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Tight positive regulation of transgene expression by a single adenovirus vector containing the rtTA and tTS expression cassettes in separate genome regions

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Efficient gene transfer by fiber-mutant adenoviral vectors containing RGD peptide

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Alpha v integrins as receptors for tumor targeting by circulating ligands.

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Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model

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A system for efficient generation of adenovirus protein IX-producing helper cell lines

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An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism

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7 January 2021

A simple method for constructing E1- and E1/E4-deleted recombinant adenoviral vectors

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7 January 2021

The polypeptides of adenovirus. I. Evidence for multiple protein components in the virion and a comparison of types 2, 7A, and 12

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7 January 2021

Comparison of adenovirus fiber, protein IX, and hexon capsomeres as scaffolds for vector purification and cell targeting

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7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302859

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Dimensions Publication ID

18 September 2017

1025384392

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