The CXCR4-SDF1alpha axis is a critical mediator of rhabdomyosarcoma metastatic signaling induced by bone marrow stroma (Q40177656)

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scientific article published on September 2007

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English	The CXCR4-SDF1alpha axis is a critical mediator of rhabdomyosarcoma metastatic signaling induced by bone marrow stroma	scientific article published on September 2007

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Europe PubMed Central

PubMed publication ID

17768666

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18 September 2017

title

The CXCR4-SDF1alpha axis is a critical mediator of rhabdomyosarcoma metastatic signaling induced by bone marrow stroma (English)

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Europe PubMed Central

PubMed publication ID

17768666

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18 September 2017

main subject

rhabdomyosarcoma

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inferred from title

author

David Malkin

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4

object named as

David Malkin

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author name string

Brigitte Strahm

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1

1 reference

stated in

Europe PubMed Central

PubMed publication ID

17768666

retrieved

18 September 2017

Adam D Durbin

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2

1 reference

stated in

Europe PubMed Central

PubMed publication ID

17768666

retrieved

18 September 2017

Elizabeth Sexsmith

series ordinal

3

1 reference

stated in

Europe PubMed Central

PubMed publication ID

17768666

retrieved

18 September 2017

publication date

1 September 2007

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stated in

Europe PubMed Central

PubMed publication ID

17768666

retrieved

18 September 2017

published in

Clinical & Experimental Metastasis

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stated in

Europe PubMed Central

PubMed publication ID

17768666

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18 September 2017

volume

25

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stated in

Europe PubMed Central

PubMed publication ID

17768666

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18 September 2017

issue

1

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Europe PubMed Central

PubMed publication ID

17768666

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18 September 2017

page(s)

1-10

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Europe PubMed Central

PubMed publication ID

17768666

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18 September 2017

cites work

Production of stromal cell-derived factor-1 (SDF-1)and expression of CXCR4 in human bone marrow endothelial cells

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Crossref

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https://api.crossref.org/works/10.1007%2FS10585-007-9094-6

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21 January 2018

The Intergroup Rhabdomyosarcoma Study-II.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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inferred from PubMed ID database lookup

Tissue microenvironment modulates CXCR4 expression and tumor metastasis in neuroblastoma

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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Interleukin-1 beta, transforming growth factor beta 1, prostaglandin E2, and fibronectin levels in the conditioned mediums of bone marrow fibroblast cultures from lung and breast cancer patients

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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Both hepatocyte growth factor (HGF) and stromal-derived factor-1 regulate the metastatic behavior of human rhabdomyosarcoma cells, but only HGF enhances their resistance to radiochemotherapy.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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Concurrent and independent genetic alterations in the stromal and epithelial cells of mammary carcinoma: implications for tumorigenesis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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Critical determinants of metastasis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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Contact between human bone marrow stromal cells and B lymphocytes enhances very late antigen-4/vascular cell adhesion molecule-1-independent tyrosine phosphorylation of focal adhesion kinase, paxillin, and ERK2 in stromal cells.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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The organ microenvironment and cancer metastasis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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inferred from PubMed ID database lookup

Silencing of CXCR4 blocks breast cancer metastasis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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Up-front window trial of topotecan in previously untreated children and adolescents with metastatic rhabdomyosarcoma: an intergroup rhabdomyosarcoma study

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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Breast cancer micrometastases: different interactions of carcinoma cells with normal and cancer patients' bone marrow stromata

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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CXCR4-SDF-1 signalling, locomotion, chemotaxis and adhesion

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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The Intergroup Rhabdomyosarcoma Study-I. A final report

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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Activation of integrin-linked kinase is a critical prosurvival pathway induced in leukemic cells by bone marrow-derived stromal cells.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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Crosstalk between cancer cells and bone microenvironment in bone metastasis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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The distribution of secondary growths in cancer of the breast. 1889

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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Molecular mechanism of AMD3100 antagonism in the CXCR4 receptor: transfer of binding site to the CXCR3 receptor

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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inferred from PubMed ID database lookup

A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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The microenvironment of the tumour-host interface

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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Mechanisms of myofibroblast activity and phenotypic modulation.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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inferred from PubMed ID database lookup

Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

based on heuristic

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Inducible short-term and stable long-term cell culture systems reveal that the PAX3-FKHR fusion oncoprotein regulates CXCR4, PAX3, and PAX7 expression

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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A Phase II Trial of High-Dose Methotrexate in Previously Untreated Children and Adolescents with High-Risk Unresectable or Metastatic Rhabdomyosarcoma

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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Do patients with metastatic and recurrent rhabdomyosarcoma benefit from high-dose therapy with hematopoietic rescue? Report of the German/Austrian Pediatric Bone Marrow Transplantation Group

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXCR4-SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukemia inhibitory factor: a newly identified metastatic factor in rhabdomyosarcomas

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic factors and clinical outcomes in children and adolescents with metastatic rhabdomyosarcoma--a report from the Intergroup Rhabdomyosarcoma Study IV.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant p53 in bone marrow stromal cells increases VEGF expression and supports leukemia cell growth

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human melanoma metastases express functional CXCR4.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stromal fibroblasts in cancer initiation and progression

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer and the chemokine network

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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inferred from PubMed ID database lookup

Stromal derived growth factor-1alpha: another mediator in neural-emerging immune system through Tac1 expression in bone marrow stromal cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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The biology of chemokines and their receptors

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Third Intergroup Rhabdomyosarcoma Study

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17768666

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the molecular pharmacology of AMD3100: a specific antagonist of the G-protein coupled chemokine receptor, CXCR4.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17768666

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased survival, proliferation, and migration in metastatic human pancreatic tumor cells expressing functional CXCR4.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of inhibitors of the chemokine receptor CXCR4 on acute lymphoblastic leukemia cells in vitro

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXCL12/CXCR4 signaling activates Akt-1 and MMP-9 expression in prostate cancer cells: the role of bone microenvironment-associated CXCL12.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17768666

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12 December 2020

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Identifiers

DOI

10.1007/S10585-007-9094-6

1 reference

stated in

Europe PubMed Central

PubMed publication ID

17768666

retrieved

18 September 2017

Dimensions Publication ID

1023727406

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PubMed publication ID

17768666

1 reference

stated in

Europe PubMed Central

PubMed publication ID

17768666

retrieved

18 September 2017

 

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