Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin. (Q40114005)

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1 January 2020

title

Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin (English)

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1 January 2020

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1 January 2020

Wallich R

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1 January 2020

Zentgraf H

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1 January 2020

Martin P

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Ekiciler A

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Prins A

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Müllbacher A

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Simon MM

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publication date

29 June 2007

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Cell Death & Differentiation

1 January 2020

published in

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volume

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issue

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page(s)

1768-1779

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Mast cells--key effector cells in immune responses

1 January 2020

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Lymphocyte-mediated cytotoxicity.

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The immunological synapse of CTL contains a secretory domain and membrane bridges.

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Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis

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Granzyme A released upon stimulation of cytotoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes

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Extracellular matrix remodeling by human granzyme B via cleavage of vitronectin, fibronectin, and laminin.

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Quiescent and activated mouse granulocytes do not express granzyme A and B or perforin: similarities or differences with human polymorphonuclear leukocytes?

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Lysosome-associated membrane proteins: characterization of LAMP-1 of macrophage P388 and mouse embryo 3T3 cultured cells

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Targeted disruption of SHIP leads to Steel factor-induced degranulation of mast cells.

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Endothelial cell-cell junctions: happy together

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An unusual specificity in the activation of neutrophil serine proteinase zymogens

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Structural requirements and mechanism for heparin-induced activation of a recombinant mouse mast cell tryptase, mouse mast cell protease-6: formation of active tryptase monomers in the presence of low molecular weight heparin

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Perforin gene defects in familial hemophagocytic lymphohistiocytosis.

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Transmigration through venular walls: a key regulator of leukocyte phenotype and function

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The extracellular matrix as a cell survival factor

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Integrins regulate VE-cadherin and catenins: dependence of this regulation on Src, but not on Ras.

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Granzyme B induces endothelial cell apoptosis and contributes to the development of transplant vascular disease

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The immune response in atherosclerosis: a double-edged sword

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Granzyme B in Atherosclerosis and Transplant Vascular Disease: Association with Cell Death and Atherosclerotic Disease Severity

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Mast cells are essential intermediaries in regulatory T-cell tolerance

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Mast cells: a cellular link between autoantibodies and inflammatory arthritis

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Staphylococcal alpha-toxin, streptolysin-O, and Escherichia coli hemolysin: prototypes of pore-forming bacterial cytolysins

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Granzymes are essential for natural killer cell-mediated and perf-facilitated tumor control

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A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis.

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The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)

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Critical protective role of mast cells in a model of acute septic peritonitis

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Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-α

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Strain-dependent inhibitory effect of mutant mi-MITF on cytotoxic activities of cultured mast cells and natural killer cells of mice

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7 January 2021

Granzyme B induces smooth muscle cell apoptosis in the absence of perforin: involvement of extracellular matrix degradation

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7 January 2021

The levels of soluble granzyme A and B are elevated in plasma and synovial fluid of patients with rheumatoid arthritis (RA)

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7 January 2021

SHIP down-regulates FcepsilonR1-induced degranulation at supraoptimal IgE or antigen levels

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Perforin-mediated target cell lysis by cytolytic T lymphocytes

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Mast cells in innate immunity

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Accumulation of activated mast cells in the shoulder region of human coronary atheroma, the predilection site of atheromatous rupture

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7 January 2021

Expression of granzymes A and B in synovial tissue from patients with rheumatoid arthritis and osteoarthritis

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7 January 2021

Expression of the C5a receptor (CD88) on synovial mast cells in patients with rheumatoid arthritis

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7 January 2021

Human mast cells produce and release the cytotoxic lymphocyte associated protease granzyme B upon activation

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7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4402183

1 reference

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Dimensions Publication ID

1 January 2020

1045253494

0 references

1 reference

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