The essential functions of KREPB4 are developmentally distinct and required for endonuclease association with editosomes (Q40096232)

17 September 2017

title

The essential functions of KREPB4 are developmentally distinct and required for endonuclease association with editosomes (English)

1 reference

17 September 2017

1 reference

17 September 2017

Kenneth Stuart

1 reference

17 September 2017

language of work or name

English

0 references

publication date

11 August 2017

1 reference

17 September 2017

1 reference

In vivo cleavage specificity of Trypanosoma brucei editosome endonucleases.

17 September 2017

cites work

1 reference

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30 August 2018

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Ribosome-associated pentatricopeptide repeat proteins function as translational activators in mitochondria of trypanosomes

30 August 2018

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30 August 2018

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Identification by Random Mutagenesis of Functional Domains in KREPB5 That Differentially Affect RNA Editing between Life Cycle Stages of Trypanosoma brucei

30 August 2018

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Differential Editosome Protein Function between Life Cycle Stages of Trypanosoma brucei

30 August 2018

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RNA binding and core complexes constitute the U-insertion/deletion editosome

30 August 2018

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Ribonuclease III mechanisms of double-stranded RNA cleavage

30 August 2018

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Identification of essential and non-essential protein kinases by a fusion PCR method for efficient production of transgenic Trypanosoma brucei

30 August 2018

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Allosteric activation of trypanosomatid deoxyhypusine synthase by a catalytically dead paralog

30 August 2018

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Mutational analysis of Trypanosoma brucei editosome proteins KREPB4 and KREPB5 reveals domains critical for function.

30 August 2018

1 reference

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Functional characterization of two paralogs that are novel RNA binding proteins influencing mitochondrial transcripts of Trypanosoma brucei

30 August 2018

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Editosome accessory factors KREPB9 and KREPB10 in Trypanosoma brucei

30 August 2018

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Architecture of the trypanosome RNA editing accessory complex, MRB1.

30 August 2018

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KREPB6, KREPB7, and KREPB8 are important for editing endonuclease function in Trypanosoma brucei.

30 August 2018

1 reference

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PhosTryp: a phosphorylation site predictor specific for parasitic protozoa of the family trypanosomatidae

30 August 2018

1 reference

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Uridine insertion/deletion editing in trypanosomes: a playground for RNA-guided information transfer

30 August 2018

1 reference

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Endonuclease Associations with Three Distinct Editosomes in Trypanosoma brucei

30 August 2018

1 reference

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Stacking interactions in PUF-RNA complexes

30 August 2018

1 reference

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Differential functions of two editosome exoUases in Trypanosoma brucei.

30 August 2018

1 reference

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The MRB1 complex functions in kinetoplastid RNA processing.

30 August 2018

1 reference

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Guide RNA-binding complex from mitochondria of trypanosomatids

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

The KREPA3 zinc finger motifs and OB-fold domain are essential for RNA editing and survival of Trypanosoma brucei

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

TbRGG2, an essential RNA editing accessory factor in two Trypanosoma brucei life cycle stages

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

TbRGG1, an essential protein involved in kinetoplastid RNA metabolism that is associated with a novel multiprotein complex.

30 August 2018

1 reference

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Mitochondrial complexes in Trypanosoma brucei: a novel complex and a unique oxidoreductase complex

30 August 2018

1 reference

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RNA editing in Trypanosoma brucei requires three different editosomes

30 August 2018

1 reference

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Heterodimer-based analysis of subunit and domain contributions to double-stranded RNA processing by Escherichia coli RNase III in vitro.

30 August 2018

1 reference

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Allosteric regulation of an essential trypanosome polyamine biosynthetic enzyme by a catalytically dead homolog

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

An essential role of KREPB4 in RNA editing and structural integrity of the editosome in Trypanosoma brucei.

30 August 2018

1 reference

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Ribonuclease revisited: structural insights into ribonuclease III family enzymes

30 August 2018

1 reference

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Engineering RNA sequence specificity of Pumilio repeats.

30 August 2018

1 reference

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Compositionally and functionally distinct editosomes in Trypanosoma brucei

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

KREPA4, an RNA binding protein essential for editosome integrity and survival of Trypanosoma brucei

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

A deletion site editing endonuclease in Trypanosoma brucei.

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

An essential RNase III insertion editing endonuclease in Trypanosoma brucei.

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

A vector series for rapid PCR-mediated C-terminal in situ tagging of Trypanosoma brucei genes.

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Complex management: RNA editing in trypanosomes

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

MUSCLE: multiple sequence alignment with high accuracy and high throughput

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Comparative analysis of editosome proteins in trypanosomatids

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Mass spectrometric analysis of the editosome and other multiprotein complexes in Trypanosoma brucei.

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

TbMP57 is a 3' terminal uridylyl transferase (TUTase) of the Trypanosoma brucei editosome

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Identification of novel components of Trypanosoma brucei editosomes

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Modular recognition of RNA by a human pumilio-homology domain

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

One functional subunit is sufficient for catalytic activity and substrate specificity of Escherichia coli endoribonuclease III artificial heterodimers.

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

An RNA ligase essential for RNA editing and survival of the bloodstream form of Trypanosoma brucei

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Association of two novel proteins, TbMP52 and TbMP48, with the Trypanosoma brucei RNA editing complex

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

The Pumilio protein binds RNA through a conserved domain that defines a new class of RNA-binding proteins

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

The structure and replication of kinetoplast DNA

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Extensive editing of CR2 maxicircle transcripts of Trypanosoma brucei predicts a protein with homology to a subunit of NADH dehydrogenase

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Quantitation of RNA editing substrates, products and potential intermediates: implications for developmental regulation

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Major transcript of the frameshifted coxII gene from trypanosome mitochondria contains four nucleotides that are not encoded in the DNA.

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Developmental aspects of uridine addition within mitochondrial transcripts of Trypanosoma brucei

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Editing of kinetoplastid mitochondrial mRNAs by uridine addition and deletion generates conserved amino acid sequences and AUG initiation codons

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

The MURF3 gene of T. brucei contains multiple domains of extensive editing and is homologous to a subunit of NADH dehydrogenase

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Organization of minicircle genes for guide RNAs in Trypanosoma brucei

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

An extensively edited mitochondrial transcript in kinetoplastids encodes a protein homologous to ATPase subunit 6.

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Trypanosoma equiperdum minicircles encode three distinct primary transcripts which exhibit guide RNA characteristics

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Guide RNAs in kinetoplastid mitochondria have a nonencoded 3′ oligo(U) tail involved in recognition of the preedited region

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Kinetoplast DNA minicircles encode guide RNAs for editing of cytochrome oxidase subunit III mRNA.

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

A model for RNA editing in kinetoplastid mitochondria: "guide" RNA molecules transcribed from maxicircle DNA provide the edited information

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Maxicircle CR1 transcripts of Trypanosoma brucei are edited and developmentally regulated and encode a putative iron-sulfur protein homologous to an NADH dehydrogenase subunit

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Guide RNAs for transcripts with developmentally regulated RNA editing are present in both life cycle stages of Trypanosoma brucei

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Mitochondrial DNA of kinetoplastids

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Cultivation and in vitro cloning or procyclic culture forms of Trypanosoma brucei in a semi-defined medium. Short communication

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5648035

Developmentally regulated addition of nucleotides within apocytochrome b transcripts in Trypanosoma brucei

30 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28802260

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1261/RNA.062786.117

1 reference

17 September 2017

0 references

1 reference