Transient down-regulation of cbfa1/Runx2 by RNA interference in murine C3H10T1/2 mesenchymal stromal cells delays in vitro and in vivo osteogenesis, but does not overtly affect chondrogenesis. (Q40007132)

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English	Transient down-regulation of cbfa1/Runx2 by RNA interference in murine C3H10T1/2 mesenchymal stromal cells delays in vitro and in vivo osteogenesis, but does not overtly affect chondrogenesis.	scientific article

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3 January 2020

Transient down-regulation of cbfa1/Runx2 by RNA interference in murine C3H10T1/2 mesenchymal stromal cells delays in vitro and in vivo osteogenesis, but does not overtly affect chondrogenesis (English)

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3 January 2020

cartilage development

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based on heuristic

inferred from title

RNA interference

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based on heuristic

inferred from title

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3 January 2020

Florence Apparailly

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3 January 2020

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Jan O Gordeladze

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3 January 2020

Claire Bony

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3 January 2020

Pascale Louis-Plence

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Christian Jorgensen

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12 January 2008

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Experimental Cell Research

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1495-1506

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3 January 2020

Tissue engineering through autologous mesenchymal stem cells.

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7 January 2021

Mesenchymal stem cells: clinical applications and biological characterization.

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Regulation of osteoblast differentiation by transcription factors

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The control of chondrogenesis

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Regulatory mechanisms in the pathways of cartilage and bone formation

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PTHrP and skeletal development

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Runx2/Cbfa1 stimulation by retinoic acid is potentiated by BMP2 signaling through interaction with Smad1 on the collagen X promoter in chondrocytes

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7 January 2021

Runx1/AML1/Cbfa2 mediates onset of mesenchymal cell differentiation toward chondrogenesis

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.12.023

7 January 2021

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

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7 January 2021

Morphological characterization of skeletal cells in Cbfa1-deficient mice

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Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development

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The Temporal and Spatial Subnuclear Organization of Skeletal Gene Regulatory Machinery: Integrating Multiple Levels of Transcriptional Control

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Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors

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Exogenously regulated stem cell-mediated gene therapy for bone regeneration.

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Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor alpha in collagen-induced arthritis.

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Two distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene

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Short-term BMP-2 expression is sufficient for in vivo osteochondral differentiation of mesenchymal stem cells

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Differential growth factor control of bone formation through osteoprogenitor differentiation

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RNA interference and human disease

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Type X collagen gene expression in mouse chondrocytes immortalized by a temperature-sensitive simian virus 40 large tumor antigen

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Effects of static magnetic fields on bone formation in rat osteoblast cultures

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Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O.

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Leptin stimulates human osteoblastic cell proliferation, de novo collagen synthesis, and mineralization: Impact on differentiation markers, apoptosis, and osteoclastic signaling

1 reference

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7 January 2021

Inhibition of osteoblast-specific transcription factor Cbfa1 by the cAMP pathway in osteoblastic cells. Ubiquitin/proteasome-dependent regulation.

1 reference

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7 January 2021

Transient suppression of PPARgamma directed ES cells into an osteoblastic lineage

1 reference

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7 January 2021

Mesenchymal stem cell sheets revitalize nonviable dense grafts: implications for repair of large-bone and tendon defects

1 reference

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7 January 2021

Runx2: a master organizer of gene transcription in developing and maturing osteoblasts

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.12.023

7 January 2021

BMP-2-induced Osterix expression is mediated by Dlx5 but is independent of Runx2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.12.023

7 January 2021

Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.12.023

7 January 2021

Enhanced expression of Runx2/PEBP2alphaA/CBFA1/AML3 during fracture healing

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The interferon-inducible p204 protein acts as a transcriptional coactivator of Cbfa1 and enhances osteoblast differentiation

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Core binding factor beta (CBFB) haploinsufficiency due to an interstitial deletion at 16q21q22 resulting in delayed cranial ossification, cleft palate, congenital heart anomalies, and feeding difficulties but favorable outcome

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The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2007.12.023

7 January 2021

AG-041R stimulates cartilage matrix synthesis without promoting terminal differentiation in rat articular chondrocytes

1 reference

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Runx2 deficiency in chondrocytes causes adipogenic changes in vitro

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Stem cells as platforms for delivery of genes to enhance cartilage repair.

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Differential effects of local application of BMP-2 or TGF-beta 1 on both articular cartilage composition and osteophyte formation

1 reference

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Cbfa1/Runx2 gene expression in articular chondrocytes of the mice temporomandibular and knee joints in vivo

1 reference

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Oxygen tension regulates chondrocyte differentiation and function during endochondral ossification.

1 reference

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Hypoxia decreases Runx2/Cbfa1 expression in human osteoblast-like cells.

1 reference

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Regulation of MMP-13 expression by RUNX2 and FGF2 in osteoarthritic cartilage

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10.1016/J.YEXCR.2007.12.023

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3 January 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18313048%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

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