CYP27A1 acts on the pre-vitamin D3 photoproduct, lumisterol, producing biologically active hydroxy-metabolites. (Q49923288)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29452159%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

title

CYP27A1 acts on the pre-vitamin D3 photoproduct, lumisterol, producing biologically active hydroxy-metabolites (English)

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17 March 2020

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17 March 2020

Wei Li

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17 March 2020

Dejian Ma

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17 March 2020

Chloe Y S Cheng

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17 March 2020

Katie M Wang

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17 March 2020

Tae-Kang Kim

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17 March 2020

Saowanee Jeayeng

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17 March 2020

Andrzej T Slominski

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17 March 2020

publication date

13 February 2018

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The Journal of Steroid Biochemistry and Molecular Biology

17 March 2020

published in

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17 March 2020

volume

181

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17 March 2020

page(s)

1-10

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Characterization of a new pathway that activates lumisterol in vivo to biologically active hydroxylumisterols

17 March 2020

cites work

1 reference

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Human CYP27A1 catalyzes hydroxylation of β-sitosterol and ergosterol.

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26 August 2018

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Products of vitamin D3 or 7-dehydrocholesterol metabolism by cytochrome P450scc show anti-leukemia effects, having low or absent calcemic activity.

26 August 2018

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Metabolism of substrates incorporated into phospholipid vesicles by mouse 25-hydroxyvitamin D3 1alpha-hydroxylase (CYP27B1).

26 August 2018

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Is the action spectrum for the UV-induced production of previtamin D3 in human skin correct?

26 August 2018

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Kinetics of vitamin D3 metabolism by cytochrome P450scc (CYP11A1) in phospholipid vesicles and cyclodextrin.

26 August 2018

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UVB-induced 1,25(OH)2D3 production and vitamin D activity in intestinal CaCo-2 cells and in THP-1 macrophages pretreated with a sterol Delta7-reductase inhibitor

26 August 2018

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Skin cancer prevention: a possible role of 1,25dihydroxyvitamin D3 and its analogs

26 August 2018

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A novel pathway for sequential transformation of 7-dehydrocholesterol and expression of the P450scc system in mammalian skin

26 August 2018

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Phospholipids modify substrate binding and enzyme activity of human cytochrome P450 27A1.

26 August 2018

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Novel sterols synthesized via the CYP27A1 metabolic pathway.

26 August 2018

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Human skin is a steroidogenic tissue: steroidogenic enzymes and cofactors are expressed in epidermis, normal sebocytes, and an immortalized sebocyte cell line (SEB-1)

26 August 2018

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26 August 2018

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26 August 2018

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26 August 2018

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26 August 2018

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26 August 2018

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26 August 2018

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26 August 2018

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26 August 2018

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12 December 2020

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12 December 2020

Kinetic and thermodynamic studies of the conversion of previtamin D3 to vitamin D3 in human skin

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12 December 2020

ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skin

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12 December 2020

The concentration of adrenodoxin reductase limits cytochrome p450scc activity in the human placenta

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12 December 2020

7-Dehydrocholesterol metabolites produced by sterol 27-hydroxylase (CYP27A1) modulate liver X receptor activity

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12 December 2020

Retinoic acid-related Orphan Receptor γ (RORγ): connecting sterol metabolism to regulation of the immune system and autoimmune disease

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12 December 2020

10.1016/J.JSBMB.2018.02.008

Identifiers

DOI

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release_537pe4isqvgqnb5g5x2newc4li

17 March 2020

Fatcat ID

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24 November 2022

mapped directly with Wikidata item

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17 March 2020

PubMed publication ID

29452159

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