Final analysis of survival outcomes in the phase 3 FIRST trial of up-front treatment for multiple myeloma (Q49761601)

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scientific article published on 17 November 2017

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English	Final analysis of survival outcomes in the phase 3 FIRST trial of up-front treatment for multiple myeloma	scientific article published on 17 November 2017

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Final analysis of survival outcomes in the phase 3 FIRST trial of up-front treatment for multiple myeloma (English)

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phase III clinical trial

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Murielle Roussel

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Murielle Roussel

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Athanasios Dimopoulos

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Meletios A Dimopoulos

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Angela Dispenzieri

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Thierry Facon

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Thierry Facon

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Kenneth C. Anderson

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Kenneth C Anderson

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Philippe Moreau

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Philippe Moreau

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Heinz Ludwig

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Heinz Ludwig

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Katja Weisel

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Katja Weisel

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Hervé Avet-Loiseau

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Michel Attal

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Michel Attal

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Andrew Belch

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Michele Cavo

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Michel Delforge

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Catarina Geraldes

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Nizar J Bahlis

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Nizar J Bahlis

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Anne Banos

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Anne Banos

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Jamie D Cavenagh

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Antonello Pinto

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Lugui Qiu

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Annette Ervin-Haynes

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Aurore Perrot

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Eileen M Boyle

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Salomon Manier

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Mohamad Mohty

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Bertrand Arnulf

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Vanessa Houck

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author name string

John V Catalano

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Je-Jung Lee

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Christine Chen

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Albert Oriol

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Javier De La Rubia

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Darrell White

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Daniel Binder

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Jin Lu

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Xavier Leleu

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22 February 2018

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http://europepmc.org/abstract/PMC/5774211

Guang Chen

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36

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5774211

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22 February 2018

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http://europepmc.org/abstract/PMC/5774211

Cyrille Hulin

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39

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5774211

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http://europepmc.org/abstract/PMC/5774211

language of work or name

English

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publication date

17 November 2017

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5774211

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22 February 2018

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http://europepmc.org/abstract/PMC/5774211

published in

Blood

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5774211

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22 February 2018

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http://europepmc.org/abstract/PMC/5774211

volume

131

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issue

3

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http://europepmc.org/abstract/PMC/5774211

page(s)

301-310

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cites work

Bortezomib with lenalidomide and dexamethasone versus lenalidomide and dexamethasone alone in patients with newly diagnosed myeloma without intent for immediate autologous stem-cell transplant (SWOG S0777): a randomised, open-label, phase 3 trial

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PubMed Central

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22 May 2018

Rate of CRL4(CRBN) substrate Ikaros and Aiolos degradation underlies differential activity of lenalidomide and pomalidomide in multiple myeloma cells by regulation of c-Myc and IRF4.

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22 May 2018

Second primary malignancies with lenalidomide therapy for newly diagnosed myeloma: a meta-analysis of individual patient data

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Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells

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The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins

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Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide

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Thalidomide for previously untreated elderly patients with multiple myeloma: meta-analysis of 1685 individual patient data from 6 randomized clinical trials

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Updated Outcomes and Impact of Age With Lenalidomide and Low-Dose Dexamethasone or Melphalan, Prednisone, and Thalidomide in the Randomized, Phase III FIRST Trial

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Consolidation and maintenance therapy with lenalidomide, bortezomib and dexamethasone (RVD) in high-risk myeloma patients

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2 November 2018

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PubMed Central

reference URL

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retrieved

30 November 2018

Identifiers

DOI

10.1182/BLOOD-2017-07-795047

1 reference

stated in

Europe PubMed Central

PMC publication ID

5774211

retrieved

22 February 2018

reference URL

http://europepmc.org/abstract/PMC/5774211

PMC publication ID

5774211

1 reference

stated in

Europe PubMed Central

PMC publication ID

5774211

retrieved

22 February 2018

reference URL

http://europepmc.org/abstract/PMC/5774211

PubMed publication ID

29150421

1 reference

stated in

Europe PubMed Central

PMC publication ID

5774211

retrieved

22 February 2018

reference URL

http://europepmc.org/abstract/PMC/5774211

 

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