Complex immunomodulatory effects of interferon-beta in multiple sclerosis include the upregulation of T helper 1-associated marker genes. (Q48791219)

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11 November 2019

title

Complex immunomodulatory effects of interferon-beta in multiple sclerosis include the upregulation of T helper 1-associated marker genes (English)

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11 November 2019

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11 November 2019

K P Wandinger

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11 November 2019

C S Stürzebecher

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11 November 2019

B Bielekova

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11 November 2019

G Detore

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11 November 2019

A Rosenwald

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11 November 2019

L M Staudt

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11 November 2019

H F McFarland

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11 November 2019

publication date

1 September 2001

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11 November 2019

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11 November 2019

volume

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11 November 2019

issue

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11 November 2019

page(s)

349-357

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Immunological aspects of demyelinating diseases

11 November 2019

cites work

1 reference

Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG)

21 January 2018

1 reference

Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype

21 January 2018

1 reference

Tumor necrosis factor-alpha messenger RNA expression in patients with relapsing-remitting multiple sclerosis is associated with disease activity

21 January 2018

1 reference

Regulation of interleukin (IL)-12 receptor beta2 subunit expression by endogenous IL-12: a critical step in the differentiation of pathogenic autoreactive T cells

21 January 2018

1 reference

Interferon beta induces interleukin-10 expression: relevance to multiple sclerosis

21 January 2018

1 reference

Type I interferons and T helper development

21 January 2018

1 reference

A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits

21 January 2018

1 reference

Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions

21 January 2018

1 reference

Increased interleukin 12 production in progressive multiple sclerosis: induction by activated CD4+ T cells via CD40 ligand

21 January 2018

1 reference

Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis

21 January 2018

1 reference

Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s

21 January 2018

1 reference

The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions

21 January 2018

1 reference

Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients

21 January 2018

1 reference

CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions

21 January 2018

1 reference

Real time quantitative PCR

21 January 2018

1 reference

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

21 January 2018

1 reference

The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression

21 January 2018

1 reference

The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses

21 January 2018

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Interferon beta results in immediate reduction of contrast-enhanced MRI lesions in multiple sclerosis patients followed by weekly MRI.

21 January 2018

1 reference

The human intracellular Mx-homologous protein is specifically induced by type I interferons.

21 January 2018

1 reference

Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system

21 January 2018

1 reference

Association between Tumor Necrosis Factor-α and Disease Progression in Patients with Multiple Sclerosis

21 January 2018

1 reference

Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2.

21 January 2018

1 reference

Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions

21 January 2018

1 reference

An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis

21 January 2018

1 reference

Tumor necrosis factor alpha and lymphotoxin alpha are not required for induction of acute experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination

21 January 2018

1 reference

Myelin Basic Protein–specific T Helper 2 (Th2) Cells Cause Experimental Autoimmune Encephalomyelitis in Immunodeficient Hosts Rather than Protect Them from the Disease

21 January 2018

1 reference

Late complications of immune deviation therapy in a nonhuman primate

21 January 2018

1 reference

Identification of autoantibodies associated with myelin damage in multiple sclerosis

21 January 2018

1 reference

Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy

21 January 2018

1 reference

Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation?

21 January 2018

1 reference

Association of human herpes virus 6 (HHV-6) with multiple sclerosis: increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA.

21 January 2018

1 reference

Association between clinical disease activity and Epstein-Barr virus reactivation in MS.

21 January 2018

1 reference

Randomised double-blind placebo-controlled study of interferon β-1a in relapsing/remitting multiple sclerosis

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/ANA.1096

1 reference

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11 November 2019

1 reference

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