Increased Susceptibility to Ischemic Brain Damage in Transgenic Mice Overexpressing the Amyloid Precursor Protein (Q48621031)

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scientific article published on October 15, 1997

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English	Increased Susceptibility to Ischemic Brain Damage in Transgenic Mice Overexpressing the Amyloid Precursor Protein	scientific article published on October 15, 1997

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scholarly article

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Europe PubMed Central

PMC publication ID

6793926

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9315887%20AND%20SRC:MED&resulttype=core&format=json

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6 November 2019

title

Increased susceptibility to ischemic brain damage in transgenic mice overexpressing the amyloid precursor protein (English)

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Europe PubMed Central

PMC publication ID

6793926

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9315887%20AND%20SRC:MED&resulttype=core&format=json

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6 November 2019

Increased Susceptibility to Ischemic Brain Damage in Transgenic Mice Overexpressing the Amyloid Precursor Protein (English)

1 reference

stated in

Crossref

DOI

10.1523/JNEUROSCI.17-20-07655.1997

reference URL

https://api.crossref.org/works/10.1523/JNEUROSCI.17-20-07655.1997

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18 November 2024

main subject

overexpression

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author name string

F. Zhang

series ordinal

1

1 reference

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Europe PubMed Central

PubMed publication ID

9315887

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9315887

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C. Eckman

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2

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Europe PubMed Central

PubMed publication ID

9315887

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9315887

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18 November 2024

S. Younkin

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3

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Europe PubMed Central

PubMed publication ID

9315887

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9315887

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18 November 2024

K. K. Hsiao

series ordinal

4

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Europe PubMed Central

PubMed publication ID

9315887

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9315887

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C. Iadecola

series ordinal

5

1 reference

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Europe PubMed Central

PubMed publication ID

9315887

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9315887

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language of work or name

English

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publication date

1 October 1997

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Europe PubMed Central

PMC publication ID

6793926

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9315887%20AND%20SRC:MED&resulttype=core&format=json

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6 November 2019

15 October 1997

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stated in

National Center for Biotechnology Information

PubMed publication ID

9315887

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9315887

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18 November 2024

full work available at URL

https://www.jneurosci.org/content/jneuro/17/20/7655.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

stated in

Europe PubMed Central

PubMed publication ID

9315887

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9315887

retrieved

18 November 2024

http://www.jneurosci.org/cgi/content/abstract/17/20/7655

online access status

open access

1 reference

stated in

Europe PubMed Central

PubMed publication ID

9315887

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9315887

retrieved

18 November 2024

https://europepmc.org/articles/PMC6793926

file format

HTML

online access status

open access

content deliverer

Europe PubMed Central

1 reference

stated in

Europe PubMed Central

PubMed publication ID

9315887

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9315887

retrieved

18 November 2024

https://europepmc.org/articles/PMC6793926?pdf=render

file format

Portable Document Format

online access status

open access

content deliverer

Europe PubMed Central

1 reference

stated in

Europe PubMed Central

PubMed publication ID

9315887

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9315887

retrieved

18 November 2024

https://doi.org/10.1523/jneurosci.17-20-07655.1997

online access status

open access

1 reference

stated in

Europe PubMed Central

PubMed publication ID

9315887

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9315887

retrieved

18 November 2024

https://syndication.highwire.org/content/doi/10.1523/JNEUROSCI.17-20-07655.1997

1 reference

stated in

Crossref

DOI

10.1523/JNEUROSCI.17-20-07655.1997

reference URL

https://api.crossref.org/works/10.1523/JNEUROSCI.17-20-07655.1997

retrieved

18 November 2024

published in

Journal of Neuroscience

1 reference

stated in

Europe PubMed Central

PMC publication ID

6793926

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9315887%20AND%20SRC:MED&resulttype=core&format=json

retrieved

6 November 2019

volume

17

1 reference

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Europe PubMed Central

PMC publication ID

6793926

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9315887%20AND%20SRC:MED&resulttype=core&format=json

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6 November 2019

issue

20

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Europe PubMed Central

PMC publication ID

6793926

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9315887%20AND%20SRC:MED&resulttype=core&format=json

retrieved

6 November 2019

page(s)

7655-7661

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Europe PubMed Central

PMC publication ID

6793926

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9315887%20AND%20SRC:MED&resulttype=core&format=json

retrieved

6 November 2019

cites work

Exploring the etiology of Alzheimer disease using molecular genetics

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

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Thresholds in cerebral ischemia - the ischemic penumbra

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spatial resolution of the primary beta-amyloidogenic process induced in postischemic hippocampus

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43).

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Infarct measurement methodology

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of delayed thrombolysis with rt-PA in a rat embolic stroke model

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of a novel inhibitor of guanylyl cyclase on dilator responses of mouse cerebral arterioles

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular signaling roles of TGF beta, TNF alpha and beta APP in brain injury responses and Alzheimer's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fastigial stimulation increases ischemic blood flow and reduces brain damage after focal ischemia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid precursor protein accumulates in regions of neurodegeneration following focal cerebral ischemia in the rat

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebrovascular responses under controlled and monitored physiological conditions in the anesthetized mouse

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Does nitric oxide mediate the increases in cerebral blood flow elicited by hypercapnia?

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional accumulation of amyloid beta/A4 protein precursor in the gerbil brain following transient cerebral ischemia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early Alzheimer disease-like histopathology increases in frequency with age in mice transgenic for beta-APP751.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of APP processing and trafficking pathways in the formation of amyloid beta-protein

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delayed postischemic hyperthermia in awake rats worsens the histopathological outcome of transient focal cerebral ischemia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid-mediated vasoactivity and vascular endothelial damage.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Viability thresholds and the penumbra of focal ischemia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide donors increase blood flow and reduce brain damage in focal ischemia: evidence that nitric oxide is beneficial in the early stages of cerebral ischemia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ionic effects of the Alzheimer's disease beta-amyloid precursor protein and its metabolic fragments

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxic fragment of amyloid precursor protein accumulates in hippocampus after global forebrain ischemia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progression from ischemic injury to infarct following middle cerebral artery occlusion in the rat.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective induction of Kunitz-type protease inhibitor domain-containing amyloid precursor protein mRNA after persistent focal ischemia in rat cerebral cortex

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects in cats of inhibition of nitric oxide synthesis on cerebral vasodilation and endothelium-derived relaxing factor from acetylcholine

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the cerebral circulation by endothelium

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Permissive and obligatory roles of NO in cerebrovascular responses to hypercapnia and acetylcholine

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of HSP70 mRNA after transient ischemia in gerbil brain

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial expression of the beta-amyloid precursor protein (APP) in global ischemia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cerebral ischemic penumbra

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secreted forms of beta-amyloid precursor protein protect against ischemic brain injury

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation of the beta amyloid precursor protein at sites of ischemic injury in rat brain.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular and molecular biology of Alzheimer's disease and animal models

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The heterogeneous temporal evolution of focal ischemic neuronal damage in the rat.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of the fastigial nucleus enhances EEG recovery and reduces tissue damage after focal cerebral ischemia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain infarction is not reduced in SOD-1 transgenic mice after a permanent focal cerebral ischemia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse strain differences in susceptibility to cerebral ischemia are related to cerebral vascular anatomy

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/9315887

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1523/JNEUROSCI.17-20-07655.1997

1 reference

stated in

Europe PubMed Central

PMC publication ID

6793926

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9315887%20AND%20SRC:MED&resulttype=core&format=json

retrieved

6 November 2019

PMC publication ID

6793926

1 reference

stated in

Europe PubMed Central

PMC publication ID

6793926

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9315887%20AND%20SRC:MED&resulttype=core&format=json

retrieved

6 November 2019

PubMed publication ID

9315887

1 reference

stated in

Europe PubMed Central

PMC publication ID

6793926

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9315887%20AND%20SRC:MED&resulttype=core&format=json

retrieved

6 November 2019

 

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