Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia (Q48616927)

13 February 2018

title

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia (English)

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13 February 2018

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A. Pieper

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M. J. Eliasson

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K. Sampei

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A. S. Mandir

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P. D. Hurn

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R. J. Traystman

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J. Bao

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Z. Q. Wang

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T. M. Dawson

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S. H. Snyder

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V. L. Dawson

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language of work or name

English

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publication date

1 October 1997

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13 February 2018

October 1997

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9334719

full work available at URL

19 November 2024

http://www.nature.com/articles/nm1097-1089

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http://www.nature.com/articles/nm1097-1089.pdf

19 November 2024

file format

Portable Document Format

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19 November 2024

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13 February 2018

volume

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13 February 2018

issue

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13 February 2018

page(s)

1089-1095

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13 February 2018

Poly(ADP-ribose) polymerase: a molecular nick-sensor

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Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia

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Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice

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Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells.

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Inhibition of the activity of poly(ADP ribose) synthetase reduces ischemia-reperfusion injury in the heart and skeletal muscle

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Excitotoxicity in the lung: N-methyl-D-aspartate-induced, nitric oxide-dependent, pulmonary edema is attenuated by vasoactive intestinal peptide and by inhibitors of poly(ADP-ribose) polymerase

21 January 2018

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DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite

21 January 2018

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Peroxynitrite causes energy depletion and increases permeability via activation of poly (ADP-ribose) synthetase in pulmonary epithelial cells

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Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase

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Antagonism of non-NMDA receptors augments the neuroprotective effect of NMDA receptor blockade in cortical cultures subjected to prolonged deprivation of oxygen and glucose

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Oxygen or glucose deprivation-induced neuronal injury in cortical cell cultures is reduced by tetanus toxin

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Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats

21 January 2018

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Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia

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Molecular and biochemical features of poly (ADP-ribose) metabolism

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7 January 2021

Structure and function of poly(ADP-ribose) polymerase

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Glutamate neurotoxicity and diseases of the nervous system

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Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures

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Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures

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Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice

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Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase

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Nitric oxide toxicity in islet cells involves poly(ADP-ribose) polymerase activation and concomitant NAD+ depletion.

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Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity

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Poly(ADP‐Ribose) Synthetase Activation: An Early Indicator of Neurotoxic DNA Damage

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7 January 2021

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease

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Inhibitors and activators of ADP-ribosylation reactions

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PARP is important for genomic stability but dispensable in apoptosis

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Cerebral hypoxia: some new approaches and unanswered questions

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Gases as biological messengers: nitric oxide and carbon monoxide in the brain

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Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase

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7 January 2021

Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase

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Roles for oxidative stress and poly(ADP-ribosyl)ation in the killing of cultured hepatocytes by methyl methanesulfonate

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7 January 2021

Reactive oxygen injury to cultured pulmonary artery endothelial cells: mediation by poly(ADP-ribose) polymerase activation causing NAD depletion and altered energy balance

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7 January 2021

Lipid peroxidation, protein thiol oxidation and DNA damage in hydrogen peroxide-induced injury to endothelial cells: role of activation of poly(ADP-ribose)polymerase

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7 January 2021

Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues

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Detection of poly(ADP-ribose) polymerase and its reaction product poly(ADP-ribose) by immunocytochemistry

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American Journal of Physiology

269

L59

BB Hudak

1995

1 reference

https://api.crossref.org/works/10.1038/NM1097-1089

19 November 2024

Identifiers

DOI

10.1038/NM1097-1089

1 reference

13 February 2018

1 reference

13 February 2018