Tau Isoforms Imbalance Impairs the Axonal Transport of the Amyloid Precursor Protein in Human Neurons. (Q48095457)

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5 April 2020

title

Tau Isoforms Imbalance Impairs the Axonal Transport of the Amyloid Precursor Protein in Human Neurons (English)

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5 April 2020

Valentina Lacovich

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5 April 2020

Matías Alloatti

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5 April 2020

Victorio Pozo Devoto

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Lucas E Cromberg

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Mária E Čarná

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Luciana Bruno

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M Elena Avale

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Tomás L Falzone

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language of work or name

English

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publication date

1 January 2017

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5 April 2020

published in

Journal of Neuroscience

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volume

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issue

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page(s)

58-69

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describes a project that uses

5 April 2020

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles

1 reference

12 December 2020

Structural and functional differences between 3-repeat and 4-repeat tau isoforms. Implications for normal tau function and the onset of neurodegenetative disease

1 reference

12 December 2020

Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress

1 reference

12 December 2020

Differential regulation of microtubule dynamics by three- and four-repeat tau: implications for the onset of neurodegenerative disease

1 reference

12 December 2020

Tau gene alternative splicing: expression patterns, regulation and modulation of function in normal brain and neurodegenerative diseases

1 reference

12 December 2020

Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease

1 reference

12 December 2020

Reprogramming of tau alternative splicing by spliceosome-mediated RNA trans-splicing: implications for tauopathies

1 reference

12 December 2020

Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?

1 reference

12 December 2020

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport

1 reference

12 December 2020

Multiple-motor based transport and its regulation by Tau.

1 reference

12 December 2020

Quantification of amyloid precursor protein and tau for the study of axonal traffic pathways.

1 reference

12 December 2020

The tau N279K exon 10 splicing mutation recapitulates frontotemporal dementia and parkinsonism linked to chromosome 17 tauopathy in a mouse model.

1 reference

12 December 2020

Interaction of tau protein with the dynactin complex

1 reference

12 December 2020

Differential regulation of dynein and kinesin motor proteins by tau

1 reference

12 December 2020

Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice

1 reference

12 December 2020

Tug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors

1 reference

12 December 2020

Role of axonal transport in neurodegenerative diseases

1 reference

12 December 2020

Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

1 reference

12 December 2020

Axonal stress kinase activation and tau misbehavior induced by kinesin-1 transport defects.

1 reference

12 December 2020

Correction of tau mis-splicing caused by FTDP-17 MAPT mutations by spliceosome-mediated RNA trans-splicing

1 reference

12 December 2020

Differentiation of neural precursors and dopaminergic neurons from human embryonic stem cells

1 reference

12 December 2020

Kinesin-1/Hsc70-dependent mechanism of slow axonal transport and its relation to fast axonal transport

1 reference

12 December 2020

The many faces of tau

1 reference

12 December 2020

Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport.

1 reference

12 December 2020

The nucleotide-binding state of microtubules modulates kinesin processivity and the ability of Tau to inhibit kinesin-mediated transport

1 reference

12 December 2020

Imaging amyloid precursor protein in vivo: an axonal transport assay.

1 reference

12 December 2020

Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila

1 reference

12 December 2020

Axonal transport and neurodegenerative disease: can we see the elephant?

1 reference

12 December 2020

Reduced axonal transport and increased excitotoxic retinal ganglion cell degeneration in mice transgenic for human mutant P301S tau.

1 reference

12 December 2020

Lessons from tau-deficient mice

1 reference

12 December 2020

Measuring molecular motor forces in vivo: implications for tug-of-war models of bidirectional transport

1 reference

12 December 2020

Force measurements on cargoes in living cells reveal collective dynamics of microtubule motors

1 reference

12 December 2020

Trans-splicing correction of tau isoform imbalance in a mouse model of tau mis-splicing

1 reference

12 December 2020

Embryonic stem cell-based modeling of tau pathology in human neurons.

1 reference

12 December 2020

Tau pathology and neurodegeneration

1 reference

12 December 2020

Biosensing MAPs as "roadblocks": kinesin-based functional analysis of tau protein isoforms and mutants using suspended microtubules (sMTs).

1 reference

12 December 2020

JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors

1 reference

12 December 2020

Global axonal transport rates are unaltered in htau mice in vivo

1 reference

12 December 2020

Tau pathology is present in vivo and develops in vitro in sensory neurons from human P301S tau transgenic mice: a system for screening drugs against tauopathies

1 reference

12 December 2020

The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons

1 reference

12 December 2020

Tau interconverts between diffusive and stable populations on the microtubule surface in an isoform and lattice specific manner

1 reference

12 December 2020

Fast axonal transport of the proteasome complex depends on membrane interaction and molecular motor function.

1 reference

12 December 2020

Biophysical challenges to axonal transport: motor-cargo deficiencies and neurodegeneration

1 reference

12 December 2020

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

1 reference

12 December 2020

Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging

1 reference

12 December 2020

Invited review: Frontotemporal dementia caused by microtubule-associated protein tau gene (MAPT) mutations: a chameleon for neuropathology and neuroimaging

1 reference

12 December 2020

Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients with MAPT mutations.

1 reference

12 December 2020

Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons

1 reference

12 December 2020

Tau physiology and pathomechanisms in frontotemporal lobar degeneration

1 reference

12 December 2020

Mutation in the tau gene in familial multiple system tauopathy with presenile dementia

1 reference

12 December 2020

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

1 reference

12 December 2020

Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease

1 reference

12 December 2020

10.1523/JNEUROSCI.2305-16.2016

Identifiers

DOI

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5 April 2020

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5 April 2020

PubMed publication ID

28053030

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