Immunoglobulin light chain class multiplicity and alternative organizational forms in early vertebrate phylogeny. (Q48086494)

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23 October 2019

title

Immunoglobulin light chain class multiplicity and alternative organizational forms in early vertebrate phylogeny (English)

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23 October 2019

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23 October 2019

J P Rast

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23 October 2019

T Ota

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23 October 2019

R T Litman

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23 October 2019

M Margittai

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23 October 2019

M J Shamblott

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23 October 2019

G W Litman

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23 October 2019

language of work or name

English

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publication date

1 January 1994

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23 October 2019

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23 October 2019

volume

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23 October 2019

issue

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23 October 2019

page(s)

83-99

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Somatic mutation of immunoglobulin light-chain variable-region genes

23 October 2019

cites work

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12 December 2020

Evolution of immunoglobulin light chains: cDNA clones specifying sandbar shark constant regions

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Complete nucleotide sequence of primitive vertebrate immunoglobulin light chain genes

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Human immunoglobulin C lambda 6 gene encodes the Kern+Oz-lambda chain and C lambda 4 and C lambda 5 are pseudogenes

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Genomic organization and sequences of immunoglobulin light chain genes in a primitive vertebrate suggest coevolution of immunoglobulin gene organization

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Evolution of immunoglobulin light chain genes: analysis of Xenopus IgL isotypes and their contribution to antibody diversity

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Molecular cloning of a bovine immunoglobulin lambda chain cDNA.

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Structure of a third murine immunoglobulin lambda light chain variable region that is expressed in laboratory mice.

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Sequence analysis of porcine immunoglobulin light chain cDNAs

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Light chain germ-line genes and the immune response to 2-phenyloxazolone.

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Complete nucleotide sequence of mouse imunoglobulin μ gene and comparison with other immunoglobulin heavy chain genes

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Immunoglobulin genes of different subgroups are interdigitated within the VK locus

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Two kappa immunoglobulin genes are expressed in the myeloma S107.

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Cloning and sequence analysis of an Ig lambda light chain mRNA expressed in the Burkitt's lymphoma cell line EB4

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Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments

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Early rearrangements of genes encoding murine immunoglobulin kappa chains, unlike genes encoding heavy chains, use variable gene segments dispersed throughout the locus

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Nucleotide sequence of Y3-Ag 1.2.3. rat myeloma immunoglobulin kappa chain cDNA.

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A rabbit Ig lambda L chain C region gene encoding C21 allotopes.

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Identification of a new V kappa gene family that is highly expressed in hybridomas from an autoimmune mouse strain.

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A single VH gene segment encodes the immune response to phosphorylcholine: somatic mutation is correlated with the class of the antibody

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V region gene usage and somatic mutation in the primary and secondary responses to influenza virus hemagglutinin.

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A cluster type organization of the loci of the immunoglobulin light chain in Atlantic cod (Gadus morhua L.) and rainbow trout (Oncorhynchus mykiss Walbaum) indicated by nucleotide sequences of cDNAs and hybridization analysis

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The immunoglobulin lambda locus in rat consists of two C lambda genes and a single V lambda gene

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Amino terminal sequence of heavy and light chains from ratfish immunoglobulin

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Variation in the crossover point of kappa immunoglobulin gene V-J recombination: evidence from a cryptic gene

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Immunoglobulin heavy chain gene organization and complexity in the skate, Raja erinacea

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A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

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Evolutionary comparison of the avian IgL locus: combinatorial diversity plays a role in the generation of the antibody repertoire in some avian species

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12 December 2020

Clustered arrangement of immunoglobulin λ constant region genes in man

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12 December 2020

Southern analysis of genomic DNA with unique and degenerate oligonucleotide probes: a method for reducing probe degeneracy

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12 December 2020

Sequences of mouse immunoglobulin light chain genes before and after somatic changes

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12 December 2020

Structure and pre-B lymphocyte restricted expression of the VpreB in humans and conservation of its structure in other mammalian species

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Characterization of allelic V kappa-1 region genes in inbred strains of mice

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Nucleic acid sequence of an internal image-bearing monoclonal anti-idiotype and its comparison to the sequence of the external antigen

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Isolation and sequence of sheep Ig H and L chain cDNA.

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12 December 2020

Conservation of the immunoglobulin C lambda 5 gene in the Mus gene

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DNA sequencing with chain-terminating inhibitors

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Complete sequence of a cDNA clone specifying sandbar shark immunoglobulin light chain: gene organization and implications for the evolution of light chains

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12 December 2020

The human VK locus. Characterization of a duplicated region encoding 28 different immunoglobulin genes

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12 December 2020

Evolution of mouse immunoglobulin lambda genes

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12 December 2020

Isolation of a shark immunoglobulin light chain cDNA clone encoding a protein resembling mammalian kappa light chains: implications for the evolution of light chains

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12 December 2020

Two distinct immunoglobulin heavy chain isotypes in a primitive, cartilaginous fish, Raja erinacea

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12 December 2020

A second gene, VpreB in the lambda 5 locus of the mouse, which appears to be selectively expressed in pre-B lymphocytes

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12 December 2020

First nucleotide sequence of a human immunoglobulin variable lambda gene belonging to subgroup II

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12 December 2020

First genomic sequence of a human Ig variable lambda gene belonging to subgroup I. Functional genes, pseudogenes and vestigial sequences are interspersed in the IGLV locus.

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12 December 2020

Genomic clone for sandbar shark lambda light chain: generation of diversity in the absence of gene rearrangement

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12 December 2020

Somatic mutation creates diversity in the major group of mouse immunoglobulin kappa light chains

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12 December 2020

On the mechanism of antibody synthesis: a species comparison of L-chains

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12 December 2020

Allelic forms of rat κ chain genes: Evidence for strong selection at the level of nucleotide sequence

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12 December 2020

Sequence of C region of L chains from Xenopus laevis Ig.

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12 December 2020

Phylogenetic diversification of immunoglobulin genes and the antibody repertoire

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12 December 2020

Complementary DNA for a human subgroup IV immunoglobulin lambda-chain

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12 December 2020

Structural analysis of a rabbit immunoglobulinx2 J-C locus reveals multiple deletions

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12 December 2020

Differences between germ-line and rearranged immunoglobulin Vκ coding sequences suggest a localized mutation mechanism

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12 December 2020

Diverse organization of immunoglobulin VH gene loci in a primitive vertebrate

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12 December 2020

Subgroup IV of human immunoglobulin K light chains is encoded by a single germline gene

1 reference

12 December 2020

Identification of a second immunoglobulin in the most primitive shark, the frill shark, Chlamydoselachus anguineus

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12 December 2020

Activation of an excluded immunoglobulin allele in a human B lymphoma cell line

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12 December 2020

Complete structure and organization of immunoglobulin heavy chain constant region genes in a phylogenetically primitive vertebrate

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12 December 2020

Recombined flanks of the variable and joining segments of immunoglobulin genes

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12 December 2020

Immunoglobulin kappa light-chain diversity in rabbit is based on the 3' length heterogeneity of germ-line variable genes

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12 December 2020

A general method applicable to the search for similarities in the amino acid sequence of two proteins

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12 December 2020

Cloning and sequencing of two functional rabbit germ-line immunoglobulin V lambda genes

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12 December 2020

Sequence of a mouse germ-line gene for a variable region of an immunoglobulin light chain

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12 December 2020

The isolation of a human Ig Vλ gene from a recombinant library of chromosome 22 and estimation of its copy number

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12 December 2020

Identification of three new Ig lambda-like genes in man

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12 December 2020

L chain isotype regulation in horse. I. Characterization of Ig lambda genes

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12 December 2020

Human immunoglobulin variable region genes--DNA sequences of two V kappa genes and a pseudogene

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12 December 2020

Characterization of four constant region genes of rabbit immunoglobulin-lambda chains

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12 December 2020

Molecular mimicry and the generation of host defense protein diversity

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12 December 2020

A hyperconversion mechanism generates the chicken light chain preimmune repertoire

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12 December 2020

A second class of immunoglobulin other than IgM present in the serum of a cartilaginous fish, the skate, Raja kenojei: Isolation and characterization

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12 December 2020

Reshaping human antibodies for therapy

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12 December 2020

Mutational hot spots in Ig V region genes of human follicular lymphomas

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12 December 2020

Identifiers

DOI

10.1007/BF00188170

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8026868%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

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