Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation. (Q47844024)

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12 March 2020

title

Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation (English)

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12 March 2020

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Stephan W Grill

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Ina Poser

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Albert C Ludolph

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Marcel Naumann

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Arun Pal

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Anand Goswami

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Xenia Lojewski

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Julia Japtok

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Anne Vehlow

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Maximilian Naujock

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Mengmeng Jin

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Nancy Stanslowsky

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Peter Reinhardt

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Marie Frickenhaus

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12 March 2020

Francisco Pan-Montojo

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Axel Freischmidt

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Jochen H Weishaupt

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Karlheinz Holzmann

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Dirk Troost

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Tobias M Boeckers

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Stefan Liebau

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Anthony A Hyman

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Florian Wegner

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Joachim Weis

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Alexander Storch

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Andreas Hermann

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Susanne Petri

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language of work or name

English

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publication date

23 January 2018

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12 March 2020

published in

Nature Communications

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volume

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issue

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page(s)

335

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Creative Commons Attribution 4.0 International

12 March 2020

start time

23 January 2018

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April 2022 Public Data File from Crossref

copyrighted

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22 May 2018

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ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects

22 May 2018

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Human iPSC models of neuronal ceroid lipofuscinosis capture distinct effects of TPP1 and CLN3 mutations on the endocytic pathway

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22 May 2018

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22 May 2018

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22 May 2018

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Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells

22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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Evidence of Increased Oxidative Damage in Both Sporadic and Familial Amyotrophic Lateral Sclerosis

22 May 2018

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Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma

22 May 2018

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A novel mutation of the C-terminal amino acid of FUS (Y526C) strengthens FUS gene as the most frequent genetic factor in aggressive juvenile ALS.

22 May 2018

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A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.

14 August 2018

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How far is the development of 13C-liver-function breath tests?

14 August 2018

1 reference

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Developmental and functional nature of human iPSC derived motoneurons

14 August 2018

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Accelerated age-related cognitive decline and neurodegeneration, caused by deficient DNA repair.

14 August 2018

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Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death.

14 August 2018

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Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

14 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41467-017-02299-1

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7 January 2021

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Rat embryonic fibroblasts improve reprogramming of human keratinocytes into induced pluripotent stem cells

1 reference

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https://api.crossref.org/works/10.1038%2FS41467-017-02299-1

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7 January 2021

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Identifiers

DOI

10.1038/S41467-017-02299-1

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12 March 2020

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12 March 2020

PubMed publication ID

29362359

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