Both CTCF-dependent and -independent insulators are found between the mouse T cell receptor alpha and Dad1 genes (Q47769588)

5 February 2018

title

Both CTCF-dependent and -independent insulators are found between the mouse T cell receptor alpha and Dad1 genes (English)

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5 February 2018

Frédérique Magdinier

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5 February 2018

Timur M. Yusufzai

series ordinal

object named as

Timur M Yusufzai

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5 February 2018

author name string

Gary Felsenfeld

series ordinal

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5 February 2018

language of work or name

English

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publication date

13 April 2004

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5 February 2018

Journal of Biological Chemistry

published in

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5 February 2018

volume

279

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issue

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5 February 2018

page(s)

25381-25389

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Comparative genomics of the human and mouse T cell receptor loci

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Alpha beta lineage-specific expression of the alpha T cell receptor gene by nearby silencers

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A new element within the T-cell receptor alpha locus required for tissue-specific locus control region activity

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Position-independent, high-level expression of the human beta-globin gene in transgenic mice

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Chromatin as an essential part of the transcriptional mechanim

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A targeted mutation at the T-cell receptor alpha/delta locus impairs T-cell development and reveals the presence of the nearby antiapoptosis gene Dad1.

21 January 2018

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The essential OST2 gene encodes the 16-kD subunit of the yeast oligosaccharyltransferase, a highly conserved protein expressed in diverse eukaryotic organisms

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Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells

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The highly conserved DAD1 protein involved in apoptosis is required for N-linked glycosylation

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Insulators: many functions, many mechanisms.

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A 5' element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila

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The repeat organizer, a specialized insulator element within the intergenic spacer of the Xenopus rRNA genes

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The protein CTCF is required for the enhancer blocking activity of vertebrate insulators

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Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

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CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

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CTCF, a candidate trans-acting factor for X-inactivation choice

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Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia

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Correlation between histone lysine methylation and developmental changes at the chicken beta-globin locus

21 January 2018

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Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci

21 January 2018

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The barrier function of an insulator couples high histone acetylation levels with specific protection of promoter DNA from methylation

21 January 2018

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Characterization of the chicken beta-globin insulator

21 January 2018

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Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold

21 January 2018

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Negative protein 1, which is required for function of the chicken lysozyme gene silencer in conjunction with hormone receptors, is identical to the multivalent zinc finger repressor CTCF.

21 January 2018

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An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes

21 January 2018

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The zinc finger protein CTCF binds to the APBbeta domain of the amyloid beta-protein precursor promoter. Evidence for a role in transcriptional activation

21 January 2018

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CTCF-binding sites flank CTG/CAG repeats and form a methylation-sensitive insulator at the DM1 locus

21 January 2018

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Structural and functional conservation at the boundaries of the chicken beta-globin domain

21 January 2018

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Control of organ-specific demethylation by an element of the T-cell receptor-alpha locus control region

21 January 2018

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Promoter suppression in cultured mammalian cells can be blocked by the chicken beta-globin chromatin insulator 5'HS4 and matrix/scaffold attachment regions

21 January 2018

1 reference

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Matrix-attachment regions can impart position-independent regulation of a tissue-specific gene in transgenic mice

21 January 2018

1 reference

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Nuclear matrix attachment regions antagonize methylation-dependent repression of long-range enhancer-promoter interactions

21 January 2018

1 reference

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Dissection of the ability of the chicken lysozyme gene 5' matrix attachment region to stimulate transgene expression and to dampen position effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403121200

CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M403121200

Visualization of chromatin domains created by the gypsy insulator of Drosophila

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M403121200

The insulator binding protein CTCF associates with the nuclear matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403121200

Position-independent transgene expression mediated by boundary elements from the apolipoprotein B chromatin domain

21 January 2018

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A nuclear DNA attachment element mediates elevated and position-independent gene activity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M403121200

21 January 2018

Identifiers

DOI

10.1074/JBC.M403121200

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5 February 2018

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5 February 2018