DNA microarray profiling of developing PS1-deficient mouse brain reveals complex and coregulated expression changes (Q47599287)

4 February 2018

title

DNA microarray profiling of developing PS1-deficient mouse brain reveals complex and coregulated expression changes (English)

1 reference

4 February 2018

1 reference

4 February 2018

author name string

Mirnics ZK

1 reference

4 February 2018

Mirnics K

1 reference

4 February 2018

Terrano D

1 reference

4 February 2018

Sisodia SS

1 reference

4 February 2018

Schor NF

1 reference

4 February 2018

language of work or name

English

0 references

publication date

1 October 2003

1 reference

4 February 2018

published in

Molecular Psychiatry

1 reference

4 February 2018

volume

1 reference

4 February 2018

issue

1 reference

4 February 2018

page(s)

863-878

1 reference

4 February 2018

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Gamma-secretase: never more enigmatic

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Presenilin, Notch, and the genesis and treatment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Nectin-1alpha, an immunoglobulin-like receptor involved in the formation of synapses, is a substrate for presenilin/gamma-secretase-like cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Complex N-linked glycosylated nicastrin associates with active gamma-secretase and undergoes tight cellular regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Abeta-like peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Proteolytic processing of low density lipoprotein receptor-related protein mediates regulated release of its intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

The Notch ligands, Delta1 and Jagged2, are substrates for presenilin-dependent "gamma-secretase" cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Are presenilins intramembrane-cleaving proteases? Implications for the molecular mechanism of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Notch and the amyloid precursor protein are cleaved by similar gamma-secretase(s).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Mutant genes in familial Alzheimer's disease and transgenic models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Additive effects of PS1 and APP mutations on secretion of the 42-residue amyloid beta-protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Skeletal and CNS defects in Presenilin-1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Presenilin-1 deficiency leads to loss of Cajal-Retzius neurons and cortical dysplasia similar to human type 2 lissencephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

The function of presenilin-1 in amyloid beta-peptide generation and brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Endogenous presenilin 1 redistributes to the surface of lamellipodia upon adhesion of Jurkat cells to a collagen matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Altered binding of mutated presenilin with cytoskeleton-interacting proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Detection of the presenilin 1 COOH-terminal fragment in the extracellular compartment: a release enhanced by apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Reelin in plaques of beta-amyloid precursor protein and presenilin-1 double-transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

beta-Amyloid peptide induces formation of actin stress fibers through p38 mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Differential display analysis of presenilin 1-deficient mouse brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

High density synthetic oligonucleotide arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

NetAffx: Affymetrix probesets and annotations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Genes and subtypes of schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Alterations in apolipoprotein E expression during aging and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Alzheimer's disease presenilin-1 expression modulates the assembly of neurofilaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Fast axonal transport misregulation and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

bHLH transcription factors and mammalian neuronal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

A new view of early cortical development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Genomic organization, sequence and chromosomal localization of the mouse Tbr2 gene and a comparative study with Tbr1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

The Notch-Hes pathway in mammalian neural development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Blocking HES1 expression initiates GABAergic differentiation and induces the expression of p21(CIP1/WAF1) in human neural stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Alzheimer's disease: neurodevelopment converges with neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

The surface of the developing cerebral cortex: still special cells one century later.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Extracellular factors that regulate neuronal migration in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Disruption of the gene encoding the acyl-CoA-binding protein (ACB1) perturbs acyl-CoA metabolism in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Peroxisome proliferator-induced long chain acyl-CoA thioesterases comprise a highly conserved novel multi-gene family involved in lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Fatty acids and hypolipidemic drugs regulate peroxisome proliferator-activated receptors alpha - and gamma-mediated gene expression via liver fatty acid binding protein: a signaling path to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

PPARbeta regulates vitamin A metabolism-related gene expression in hepatic stellate cells undergoing activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

From cholesterol transport to signal transduction: low density lipoprotein receptor, very low density lipoprotein receptor, and apolipoprotein E receptor-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Acetyl-CoA synthetase 2, a mitochondrial matrix enzyme involved in the oxidation of acetate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Role of stearoyl-coenzyme A desaturase in lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

ATP-binding cassette transporter A1, fatty acids, and cholesterol absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Regulation of lipocalin-type prostaglandin D synthase gene expression by Hes-1 through E-box and interleukin-1 beta via two NF-kappa B elements in rat leptomeningeal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Rat PPAR delta contains a CGG triplet repeat and is prominently expressed in the thalamic nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Cerebral protein kinase C and its mRNA level in apolipoprotein E-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Notch-1 controls the expression of fatty acid-activated transcription factors and is required for adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Neurofibrillary tangles and β-amyloid deposits in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Metallothionein-III inhibits initial neurite formation in developing neurons as well as postinjury, regenerative neurite sprouting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Growth inhibitory factor prevents neurite extension and the death of cortical neurons caused by high oxygen exposure through hydroxyl radical scavenging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

The effects of aging on gene expression in the hypothalamus and cortex of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

High affinity binding and overlapping localization of neurocan and phosphacan/protein-tyrosine phosphatase-zeta/beta with tenascin-R, amphoterin, and the heparin-binding growth-associated molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

Cellular localization of the diazepam binding inhibitor in glial cells with special reference to its coexistence with brain-type fatty acid binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

HES and HERP families: multiple effectors of the Notch signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

The human genome: gene expression profiling and schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

7 January 2021

A critical function of the pial basement membrane in cortical histogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

7 January 2021

Role of acyl-CoA binding protein in acyl-CoA metabolism and acyl-CoA-mediated cell signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

7 January 2021

Localization of the peroxisome proliferator-activated receptor in the brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

7 January 2021

Recent update on the PPARα-null mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001389

7 January 2021

Identifiers

DOI

10.1038/SJ.MP.4001389

1 reference

4 February 2018

1 reference

4 February 2018