Reconceptualization of translocator protein as a biomarker of neuroinflammation in psychiatry. (Q47331971)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29203847%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

review article

1 reference

title

Reconceptualization of translocator protein as a biomarker of neuroinflammation in psychiatry (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29203847%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

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1 reference

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5 April 2020

1 reference

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5 April 2020

T Notter

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5 April 2020

A Sawa

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5 April 2020

language of work or name

English

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publication date

5 December 2017

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5 April 2020

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5 April 2020

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5 April 2020

page(s)

36-47

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What is immune privilege (not)?

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Imaging of Glial Cell Activation and White Matter Integrity in Brains of Active and Recently Retired National Football League Players.

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Neuroinflammatory component of gray matter pathology in multiple sclerosis

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Hippocampal Neuroinflammation, Functional Connectivity, and Depressive Symptoms in Multiple Sclerosis.

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Intrinsic activated microglia map to the peri-infarct zone in the subacute phase of ischemic stroke.

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The temporal dynamics of poststroke neuroinflammation: a longitudinal diffusion tensor imaging-guided PET study with 11C-PK11195 in acute subcortical stroke

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Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies

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Expression of the translocator protein of 18 kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brain

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Increased central microglial activation associated with peripheral cytokine levels in premanifest Huntington's disease gene carriers

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In vivo markers of inflammatory response in recent-onset schizophrenia: a combined study using [(11)C]DPA-713 PET and analysis of CSF and plasma

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Lower levels of the glial cell marker TSPO in drug-naive first-episode psychosis patients as measured using PET and [11C]PBR28.

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Microglia Function in the Central Nervous System During Health and Neurodegeneration

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Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study

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Cerebrospinal fluid and serum cytokine profiling to detect immune control of infectious and inflammatory neurological and psychiatric diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Mitochondria in activated microglia in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

The development, past achievements, and future directions of brain PET

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Functional neuroimaging in schizophrenia: diagnosis and drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

How have developments in molecular imaging techniques furthered schizophrenia research?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

The enduring centrality of dopamine in the pathophysiology of schizophrenia: in vivo evidence from the prodrome to the first psychotic episode.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Alterations in cortical and extrastriatal subcortical dopamine function in schizophrenia: systematic review and meta-analysis of imaging studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Microglia activation in recent-onset schizophrenia: a quantitative (R)-[11C]PK11195 positron emission tomography study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Microglial Activity in People at Ultra High Risk of Psychosis and in Schizophrenia: An [(11)C]PBR28 PET Brain Imaging Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Targeting microglia-mediated neurotoxicity: the potential of NOX2 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Efficacy of anti-inflammatory agents to improve symptoms in patients with schizophrenia: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Effectiveness and tolerance of anti-inflammatory drugs' add-on therapy in major mental disorders: a systematic qualitative review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

The role of inflammation in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Macrophage phenotypes during tissue repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Selective increase of cerebrospinal fluid IL-6 during experimental systemic inflammation in humans: association with depressive symptoms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Fluorodeoxyglucose PET in Neurology and Psychiatry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

PET Imaging of Mitochondrial Complex I with 18F-BCPP-EF in the Brains of MPTP-Treated Monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Marked reduction of soluble superoxide dismutase-1 (SOD1) in cerebrospinal fluid of patients with recent-onset schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Reduced superoxide dismutase-1 (SOD1) in cerebrospinal fluid of patients with early psychosis in association with clinical features

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Molecular substrates of schizophrenia: homeostatic signaling to connectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Implications for reactive oxygen species in schizophrenia pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Redox dysregulation, neuroinflammation, and NMDA receptor hypofunction: A "central hub" in schizophrenia pathophysiology?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Oxidative stress-driven parvalbumin interneuron impairment as a common mechanism in models of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Design, Synthesis, and Evaluation of an (18)F-Labeled Radiotracer Based on Celecoxib-NBD for Positron Emission Tomography (PET) Imaging of Cyclooxygenase-2 (COX-2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

PET imaging of cyclooxygenase-2 (COX-2) in a pre-clinical colorectal cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Prostaglandins and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Soluble epoxide hydrolase is a therapeutic target for acute inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Gene deficiency and pharmacological inhibition of soluble epoxide hydrolase confers resilience to repeated social defeat stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

18F-FNDP for PET Imaging of Soluble Epoxide Hydrolase (sEH)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Distribution and expression of soluble epoxide hydrolase in human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Neuronal and nonneuronal COX-2 expression confers neurotoxic and neuroprotective phenotypes in response to excitotoxin challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Microglia, seen from the CX3CR1 angle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

MRI/MRS in neuroinflammation: methodology and applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

In vivo imaging of neuroinflammation in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

The extent of diffusion MRI markers of neuroinflammation and white matter deterioration in chronic schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

Alterations in frontal white matter neurochemistry and microstructure in schizophrenia: implications for neuroinflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

The immune system and schizophrenia. An integrative view.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

7 January 2021

Meta-analysis of Cerebrospinal Fluid Cytokine and Tryptophan Catabolite Alterations in Psychiatric Patients: Comparisons Between Schizophrenia, Bipolar Disorder, and Depression

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

7 January 2021

Chronological study of peripheral benzodiazepine binding sites in the rat brain stab wounds using [3H] PK-11195 as a marker for gliosis

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

7 January 2021

Peripheral-type benzodiazepine receptor function in cholesterol transport. Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus pattern

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

7 January 2021

Peripheral benzodiazepine receptor regulates vascular endothelial activations via suppression of the voltage-dependent anion channel-1

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

7 January 2021

Kinetic modelling of [(11)C]PBR28 for 18 kDa translocator protein PET data: A validation study of vascular modelling in the brain using XBD173 and tissue analysis.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

7 January 2021

PK ('peripheral benzodiazepine')--binding sites in the CNS indicate early and discrete brain lesions: microautoradiographic detection of [3H]PK11195 binding to activated microglia

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

7 January 2021

The upregulation of translocator protein (18 kDa) promotes recovery from neuropathic pain in rats

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

7 January 2021

Translocator Protein (18 kDa) Mapping with [125I]-CLINDE in the Quinolinic Acid Rat Model of Excitotoxicity: A Longitudinal Comparison with Microglial Activation, Astrogliosis, and Neuronal Death

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

7 January 2021

The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

7 January 2021

Pathogenesis of brain and spinal cord atrophy in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

7 January 2021

Inflammatory processes in schizophrenia: a promising neuroimmunological target for the treatment of negative/cognitive symptoms and beyond

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

7 January 2021

Relation between plasmatic and cerebrospinal fluid oxidative stress biomarkers and intrathecal Ig synthesis in Multiple Sclerosis patients

1 reference

https://api.crossref.org/works/10.1038%2FMP.2017.232

7 January 2021

The peripheral-type benzodiazepine receptor is functionally linked to Leydig cell steroidogenesis.

1 reference

12 December 2020

The peripheral-type benzodiazepine receptor. Localization to the mitochondrial outer membrane

1 reference

12 December 2020

Local distribution of microglia in the normal adult human central nervous system differs by up to one order of magnitude

1 reference

12 December 2020

Ligands of the mitochondrial 18 kDa translocator protein attenuate apoptosis of human glioblastoma cells exposed to erucylphosphohomocholine

1 reference

12 December 2020

Brain imaging for oxidative stress and mitochondrial dysfunction in neurodegenerative diseases.

1 reference

12 December 2020

The 18-kDa Translocator Protein Inhibits Vascular Cell Adhesion Molecule-1 Expression via Inhibition of Mitochondrial Reactive Oxygen Species

1 reference

12 December 2020

Lentiviral-Mediated Overexpression of the 18 kDa Translocator Protein (TSPO) in the Hippocampal Dentate Gyrus Ameliorates LPS-Induced Cognitive Impairment in Mice

1 reference

12 December 2020

Identifiers

DOI

10.1038/MP.2017.232

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29203847%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29203847%20AND%20SRC:MED&resulttype=core&format=json