Disposition of 9-nitrocamptothecin and its 9-aminocamptothecin metabolite in relation to ABC transporter genotypes (Q46967012)

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scientific article published in September 2006

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English	Disposition of 9-nitrocamptothecin and its 9-aminocamptothecin metabolite in relation to ABC transporter genotypes	scientific article published in September 2006

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Europe PubMed Central

PubMed publication ID

16505951

retrieved

26 December 2017

reference URL

http://europepmc.org/abstract/MED/16505951

title

Disposition of 9-nitrocamptothecin and its 9-aminocamptothecin metabolite in relation to ABC transporter genotypes (English)

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Europe PubMed Central

PubMed publication ID

16505951

retrieved

26 December 2017

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http://europepmc.org/abstract/MED/16505951

author name string

William C Zamboni

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1

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Europe PubMed Central

PubMed publication ID

16505951

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26 December 2017

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http://europepmc.org/abstract/MED/16505951

Ramesh K Ramanathan

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2

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Europe PubMed Central

PubMed publication ID

16505951

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26 December 2017

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http://europepmc.org/abstract/MED/16505951

Howard L McLeod

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3

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Europe PubMed Central

PubMed publication ID

16505951

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26 December 2017

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http://europepmc.org/abstract/MED/16505951

Sridhar Mani

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4

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PubMed publication ID

16505951

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26 December 2017

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Douglas M Potter

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5

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PubMed publication ID

16505951

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26 December 2017

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http://europepmc.org/abstract/MED/16505951

Sandra Strychor

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6

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PubMed publication ID

16505951

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26 December 2017

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Lauren J Maruca

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7

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PubMed publication ID

16505951

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26 December 2017

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http://europepmc.org/abstract/MED/16505951

Cristi R King

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8

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Europe PubMed Central

PubMed publication ID

16505951

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26 December 2017

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http://europepmc.org/abstract/MED/16505951

Laura L Jung

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9

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PubMed publication ID

16505951

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26 December 2017

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http://europepmc.org/abstract/MED/16505951

Robert A Parise

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10

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Europe PubMed Central

PubMed publication ID

16505951

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26 December 2017

reference URL

http://europepmc.org/abstract/MED/16505951

Merrill J Egorin

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11

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Europe PubMed Central

PubMed publication ID

16505951

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26 December 2017

reference URL

http://europepmc.org/abstract/MED/16505951

Todd A Davis

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12

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PubMed publication ID

16505951

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26 December 2017

reference URL

http://europepmc.org/abstract/MED/16505951

Sharon Marsh

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13

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PubMed publication ID

16505951

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26 December 2017

reference URL

http://europepmc.org/abstract/MED/16505951

publication date

1 September 2006

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PubMed publication ID

16505951

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26 December 2017

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http://europepmc.org/abstract/MED/16505951

published in

Investigational New Drugs

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Europe PubMed Central

PubMed publication ID

16505951

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26 December 2017

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http://europepmc.org/abstract/MED/16505951

volume

24

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Europe PubMed Central

PubMed publication ID

16505951

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26 December 2017

reference URL

http://europepmc.org/abstract/MED/16505951

issue

5

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Europe PubMed Central

PubMed publication ID

16505951

retrieved

26 December 2017

reference URL

http://europepmc.org/abstract/MED/16505951

page(s)

393-401

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PubMed publication ID

16505951

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26 December 2017

reference URL

http://europepmc.org/abstract/MED/16505951

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A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance

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12 December 2020

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Phase I clinical and pharmacological studies of 20-(S)-camptothecin and 20-(S)-9-nitrocamptothecin as anticancer agents

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12 December 2020

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Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database

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PubMed

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12 December 2020

based on heuristic

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Multicentre phase II and pharmacokinetic study of RFS2000 (9-nitro-camptothecin) administered orally 5 days a week in patients with glioblastoma multiforme

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and pharmacokinetic study evaluating the effect of food on the disposition of 9-nitrocamptothecin and its 9-aminocamptothecin metabolite in patients with solid tumors

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The clinical development of 9-aminocamptothecin.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolution of ATP-binding cassette transporter genes

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

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Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

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Phase II trial of 9-aminocamptothecin administered as a 72-hour continuous infusion in metastatic colorectal carcinoma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of the in vivo and in vitro conversion of 9-nitro-20(S)-camptothecin to 9-amino-20(S)-camptothecin in humans, dogs, and mice.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidrug resistance and pharmacological protection mediated by the breast cancer resistance protein (BCRP/ABCG2).

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of the breast cancer resistance protein on the cellular accumulation and cytotoxicity of 9-aminocamptothecin and 9-nitrocamptothecin

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation between 9-aminocamptothecin systemic exposure and tumor response in human solid tumor xenografts.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

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Development of an optimal pharmacokinetic sampling schedule for rubitecan administered orally in a daily times five schedule

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of half-transporters in multidrug resistance

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A multidrug resistance transporter from human MCF-7 breast cancer cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diflomotecan pharmacokinetics in relation to ABCG2 421C>A genotype

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irinotecan pathway genotype analysis to predict pharmacokinetics

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interpatient variability in bioavailability of the intravenous formulation of topotecan given orally to children with recurrent solid tumors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ABC transporters and inhibitors: new targets, new agents.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The intestinal absorption of camptothecin, a highly lipophilic drug, across Caco-2 cells is mediated by active transporter(s)

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I and pharmacokinetic trial of oral irinotecan administered daily for 5 days every 3 weeks in patients with solid tumors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Score tests for association between traits and haplotypes when linkage phase is ambiguous

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ABCG2 pharmacogenetics: ethnic differences in allele frequency and assessment of influence on irinotecan disposition

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inter- and intrapatient variability in oral topotecan pharmacokinetics: implications for body-surface area dosage regimens.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pretreatment with ranitidine does not reduce the bioavailability of orally administered topotecan.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of pH and serum albumin in the metabolic conversion of 9‐nitrocamptothecin to 9‐aminocamptothecin by human hematopoietic and other cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical phase II study and pharmacological evaluation of rubitecan in non-pretreated patients with metastatic colorectal cancer-significant effect of food intake on the bioavailability of the oral camptothecin analogue

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic studies of 9-nitrocamptothecin on intermittent and continuous schedules of administration in patients with solid tumors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pilot study of protracted topotecan dosing using a pharmacokinetically guided dosing approach in children with solid tumors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16505951

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S10637-006-6335-5

1 reference

stated in

Europe PubMed Central

PubMed publication ID

16505951

retrieved

26 December 2017

reference URL

http://europepmc.org/abstract/MED/16505951

PubMed publication ID

16505951

1 reference

stated in

Europe PubMed Central

PubMed publication ID

16505951

retrieved

26 December 2017

reference URL

http://europepmc.org/abstract/MED/16505951

 

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