Bone morphogenetic protein 2 opposes Shh-mediated proliferation in cerebellar granule cells through a TIEG-1-based regulation of Nmyc. (Q46939297)

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9 January 2020

title

Bone morphogenetic protein 2 opposes Shh-mediated proliferation in cerebellar granule cells through a TIEG-1-based regulation of Nmyc (English)

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9 January 2020

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9 January 2020

author name string

Rubén Alvarez-Rodríguez

series ordinal

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9 January 2020

Mercedes Barzi

series ordinal

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9 January 2020

Jordi Berenguer

series ordinal

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9 January 2020

language of work or name

English

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publication date

19 October 2007

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Journal of Biological Chemistry

9 January 2020

published in

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volume

282

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issue

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page(s)

37170-37180

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Mechanisms of Neural Patterning and Specification in the Development Cerebellum

9 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

The Hedgehog response network: sensors, switches, and routers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Developmental roles and clinical significance of hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Mutations in SUFU predispose to medulloblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Identification of an amplified, highly expressed gene in a human glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

N-myc proto-oncogene expression during organogenesis in the developing mouse as revealed by in situ hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

A comparative analysis of N-myc and c-myc expression and cellular proliferation in mouse organogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

cAMP, an activator of protein kinase A, suppresses the expression of sonic hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Bmp2 antagonizes sonic hedgehog-mediated proliferation of cerebellar granule neurones through Smad5 signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Id genes are direct targets of bone morphogenetic protein induction in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Direct interaction of c-Myc with Smad2 and Smad3 to inhibit TGF-beta-mediated induction of the CDK inhibitor p15(Ink4B)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

c-myc is a downstream target of the Smad pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Overexpression of a nuclear protein, TIEG, mimics transforming growth factor-beta action in human osteoblast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Overexpression of the TGFbeta-regulated zinc finger encoding gene, TIEG, induces apoptosis in pancreatic epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

A noncommercial dual luciferase enzyme assay system for reporter gene analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

The seven-transmembrane receptor smoothened cell-autonomously induces multiple ventral cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

The zinc finger transcription factor transforming growth factor beta-inducible early gene-1 confers myeloid-specific activation of the leukocyte integrin CD11d promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

The TGF? inducible early gene plays a central role in the anti-proliferative response to TGF?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Signaling disrupts mSin3A binding to the Mad1-like Sin3-interacting domain of TIEG2, an Sp1-like repressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

Zinc finger point mutations within the WT1 gene in Wilms tumor patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

E2F proteins regulate MYCN expression in neuroblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

N-myc oncogene expression in neuroblastoma is driven by Sp1 and Sp3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

E2F and Sp1/Sp3 Synergize but are not sufficient to activate the MYCN gene in neuroblastomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

The family feud: turning off Sp1 by Sp1-like KLF proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705414200

21 January 2018

Identifiers

DOI

10.1074/JBC.M705414200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17951258%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17951258%20AND%20SRC:MED&resulttype=core&format=json