Preclinical evidence that sildenafil and vardenafil activate chloride transport in cystic fibrosis (Q46897526)

26 December 2017

title

Preclinical evidence that sildenafil and vardenafil activate chloride transport in cystic fibrosis (English)

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26 December 2017

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Teresinha Leal

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26 December 2017

author name string

Bob Lubamba

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26 December 2017

Hugues Lecourt

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26 December 2017

Jean Lebacq

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26 December 2017

Patrick Lebecque

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26 December 2017

Hugo De Jonge

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26 December 2017

Pierre Wallemacq

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26 December 2017

language of work or name

English

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publication date

15 November 2007

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26 December 2017

American Journal of Respiratory and Critical Care Medicine

published in

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26 December 2017

volume

177

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26 December 2017

issue

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26 December 2017

page(s)

506-515

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26 December 2017

Identification of the cystic fibrosis gene: genetic analysis

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Cystic fibrosis transmembrane conductance regulator inverts protein kinase A-mediated regulation of epithelial sodium channel single channel kinetics

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Regulation of epithelial sodium channels by the cystic fibrosis transmembrane conductance regulator

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In vivo nasal potential difference: techniques and protocols for assessing efficacy of gene transfer in cystic fibrosis

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Nasal application of the cationic liposome DC-Chol:DOPE does not alter ion transport, lung function or bacterial growth

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Sildenafil (Viagra) corrects DeltaF508-CFTR location in nasal epithelial cells from patients with cystic fibrosis.

21 January 2018

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Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group

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Successful protocol of anaesthesia for measuring transepithelial nasal potential difference in spontaneously breathing mice

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Basic protocol for transepithelial nasal potential difference measurements

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Site-specific effect of guanosine 3',5'-cyclic monophosphate phosphodiesterase inhibition in isolated lamb lungs.

21 January 2018

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Inhibition of lung phosphodiesterase improves responsiveness to inhaled nitric oxide in isolated-perfused lungs from rats challenged with endotoxin

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Comparison of clinical trials with sildenafil, vardenafil and tadalafil in erectile dysfunction

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Binding of tritiated sildenafil, tadalafil, or vardenafil to the phosphodiesterase-5 catalytic site displays potency, specificity, heterogeneity, and cGMP stimulation

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Role of GTP-binding proteins in the regulation of mammalian cardiac chloride conductance.

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Chloride Conductance Expressed by ΔF508 and Other Mutant CFTRs In Xenopus Oocytes

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Adenosine receptors and phosphodiesterase inhibitors stimulate Cl- secretion in Calu-3 cells

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Activation of wild-type and deltaF508-CFTR by phosphodiesterase inhibitors through cAMP-dependent and -independent mechanisms

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A cyclic nucleotide PDE5 inhibitor corrects defective mucin secretion in submandibular cells containing antibody directed against the cystic fibrosis transmembrane conductance regulator protein

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Coupling modes and stoichiometry of Cl-/HCO3- exchange by slc26a3 and slc26a6

21 January 2018

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Vasoactive intestinal peptide, forskolin, and genistein increase apical CFTR trafficking in the rectal gland of the spiny dogfish, Squalus acanthias. Acute regulation of CFTR trafficking in an intact epithelium

21 January 2018

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Membrane targeting of cGMP-dependent protein kinase is required for cystic fibrosis transmembrane conductance regulator Cl- channel activation

21 January 2018

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Hyperacidification in cystic fibrosis: links with lung disease and new prospects for treatment

21 January 2018

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Effect of phosphodiesterase-5 inhibitor, sildenafil (Viagra), in animal models of airways disease

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S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover

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10.1164/RCCM.200703-344OC

21 January 2018

Identifiers

DOI

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26 December 2017

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26 December 2017