Towards personalised allele-specific CRISPR gene editing to treat autosomal dominant disorders. (Q46663082)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29170458%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

title

Towards personalised allele-specific CRISPR gene editing to treat autosomal dominant disorders (English)

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4 April 2020

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4 April 2020

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4 April 2020

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4 April 2020

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4 April 2020

author name string

Shyamasree De Majumdar

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4 April 2020

Laura C Mairs

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4 April 2020

M Andrew Nesbit

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4 April 2020

C B Tara Moore

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4 April 2020

language of work or name

English

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publication date

23 November 2017

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4 April 2020

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volume

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issue

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page(s)

16174

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Creative Commons Attribution 4.0 International

4 April 2020

start time

23 November 2017

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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Different Effects of sgRNA Length on CRISPR-mediated Gene Knockout Efficiency

24 May 2018

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Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo

24 May 2018

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Exploiting the CRISPR/Cas9 PAM Constraint for Single-Nucleotide Resolution Interventions

24 May 2018

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Rationally engineered Cas9 nucleases with improved specificity

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24 May 2018

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CRISPR/Cas9 DNA cleavage at SNP-derived PAM enables both in vitro and in vivo KRT12 mutation-specific targeting

24 May 2018

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In vivo genome editing using Staphylococcus aureus Cas9

24 May 2018

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Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

24 May 2018

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Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

24 May 2018

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DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.

24 May 2018

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Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

24 May 2018

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Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.

24 May 2018

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Genome engineering using the CRISPR-Cas9 system

24 May 2018

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High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

24 May 2018

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DNA targeting specificity of RNA-guided Cas9 nucleases

24 May 2018

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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

24 May 2018

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RNA-guided editing of bacterial genomes using CRISPR-Cas systems

24 May 2018

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RNA-guided human genome engineering via Cas9

24 May 2018

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Multiplex genome engineering using CRISPR/Cas systems

24 May 2018

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Allele-specific siRNA silencing for the common keratin 12 founder mutation in Meesmann epithelial corneal dystrophy

24 May 2018

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

24 May 2018

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Development of allele-specific therapeutic siRNA in Meesmann epithelial corneal dystrophy

24 May 2018

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Development of allele-specific therapeutic siRNA for keratin 5 mutations in epidermolysis bullosa simplex

24 May 2018

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Clinical Findings and Treatments of Granular Corneal Dystrophy Type 2 (Avellino Corneal Dystrophy): A Review of the Literature

24 May 2018

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24 May 2018

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Genetics of anterior and stromal corneal dystrophies

24 May 2018

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A new L527R mutation of the betaIGH3 gene in patients with lattice corneal dystrophy with deep stromal opacities

24 May 2018

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Kerato-epithelin mutations in four 5q31-linked corneal dystrophies

24 May 2018

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Engineered Cpf1 variants with altered PAM specificities

24 May 2018

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siRNA silencing of the mutant keratin 12 allele in corneal limbal epithelial cells grown from patients with Meesmann's epithelial corneal dystrophy.

15 August 2018

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Development of allele-specific gene-silencing siRNAs for TGFBI Arg124Cys in lattice corneal dystrophy type I.

15 August 2018

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The IC3D classification of the corneal dystrophies

15 August 2018

1 reference

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Prevalence of granular corneal dystrophy type 2 (Avellino corneal dystrophy) in the Korean population.

15 August 2018

1 reference

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BIGH3 mutation spectrum in corneal dystrophies

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5701044

A novel mutation at codon 124 (R124L) in the BIGH3 gene is associated with a superficial variant of granular corneal dystrophy

3 November 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-16279-4

7 January 2021

Linkage Mapping of Thiel–Behnke Corneal Dystrophy (CDB2) to Chromosome 10q23–q24

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-16279-4

7 January 2021

Association of autosomal dominantly inherited corneal dystrophies with BIGH3 gene mutations in Japan

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-16279-4

7 January 2021

Cell turnover in the adult human eye

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-16279-4

7 January 2021

10.1038/S41598-017-16279-4

Identifiers

DOI

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4 April 2020

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4 April 2020

PubMed publication ID

29170458

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29170458%20AND%20SRC:MED&resulttype=core&format=json