Fragmentation of a recombinant monoclonal antibody at various pH. (Q46600646)

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scientific article published on 13 May 2008

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English	Fragmentation of a recombinant monoclonal antibody at various pH.	scientific article published on 13 May 2008

Statements

instance of

scholarly article

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18473123

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/18473123

title

Fragmentation of a recombinant monoclonal antibody at various pH. (English)

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18473123

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/18473123

main subject

antibody

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based on heuristic

inferred from title

monoclonal antibody

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based on heuristic

inferred from title

author name string

Georgeen Gaza-Bulseco

series ordinal

1

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18473123

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/18473123

Hongcheng Liu

series ordinal

2

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18473123

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/18473123

publication date

13 May 2008

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18473123

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/18473123

published in

Pharmaceutical Research

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18473123

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/18473123

volume

25

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18473123

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/18473123

issue

8

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18473123

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/18473123

page(s)

1881-1890

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18473123

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/18473123

cites work

Development of an analytical reversed-phase high-performance liquid chromatography-electrospray ionization mass spectrometry method for characterization of recombinant antibodies

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1007%2FS11095-008-9606-3

retrieved

21 January 2018

Degradation of protein disulphide bonds in dilute alkali

1 reference

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Crossref

reference URL

https://api.crossref.org/works/10.1007%2FS11095-008-9606-3

retrieved

21 January 2018

Studies of aglycosylated chimeric mouse-human IgG. Role of carbohydrate in the structure and effector functions mediated by the human IgG constant region

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monitoring of IgG antibody thermal stability by micellar electrokinetic capillary chromatography and matrix-assisted laser desorption/ionization mass spectrometry.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Understanding base-assisted desulfurization using a variety of disulfide-bridged peptides

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fragmentation of immunoglobulin during storage

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of alkali on proteins. Disulfides and their products

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

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inferred from PubMed ID database lookup

A protein structural change in aglycosylated IgG3 correlates with loss of huFc gamma R1 and huFc gamma R111 binding and/or activation

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective cleavage of human IgG by the matrix metalloproteinases, matrilysin and stromelysin

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

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inferred from PubMed ID database lookup

Non-enzymatic hinge region fragmentation of antibodies in solution

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proton nuclear magnetic resonance studies of the structure of the Fc fragment of human immunoglobulin G1: comparisons of native and recombinant proteins

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

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inferred from PubMed ID database lookup

Identification of cysteinylation of a free cysteine in the Fab region of a recombinant monoclonal IgG1 antibody using Lys-C limited proteolysis coupled with LC/MS analysis.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical and physical stability of chimeric L6, a mouse-human monoclonal antibody

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural effect of a recombinant monoclonal antibody on hinge region peptide bond hydrolysis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of immunoglobulin G by excretory-secretory cathepsin S-like protease of Spirometra mansoni plerocercoid

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Large increase in thermal stability of the CH2 domain of rabbit IgG after acid treatment as evidenced by differential scanning calorimetry

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of posttranslational modifications on the thermal stability of a recombinant monoclonal antibody

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of glycosylation on the thermal stability and effector function expression of human IgG1-Fc: properties of a series of truncated glycoforms.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orthoclone OKT3. Chemical mechanisms and functional effects of degradation of a therapeutic monoclonal antibody

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

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12 December 2020

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inferred from PubMed ID database lookup

Fasciola hepatica: A secreted cathepsin L-like proteinase cleaves host immunoglobulin

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

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12 December 2020

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Thermodynamic and functional characterization of a stable IgG conformer obtained by renaturation from a partially structured low pH‐induced state

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimization of a reversed-phase high-performance liquid chromatography/mass spectrometry method for characterizing recombinant antibody heterogeneity and stability

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural effect of deglycosylation and methionine oxidation on a recombinant monoclonal antibody

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[A stable conformer of IgG, prepared by an acidic influence: study by calorimetry, binding of the C1q complement component, and monospecific anti-IgG]

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of pH, hydrogen peroxide and temperature on the stability of human monoclonal antibody

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

pH-dependent isoform transitions of a monoclonal antibody monitored by micellar electrokinetic capillary chromatography

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-elimination and peptide bond hydrolysis: two distinct mechanisms of human IgG1 hinge fragmentation upon storage

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analytical approaches to the study of monoclonal antibody stability

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the stability of a fully human monoclonal IgG after prolonged incubation at elevated temperature

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fasciola hepatica: parasite-secreted proteinases degrade all human IgG subclasses: determination of the specific cleavage sites and identification of the immunoglobulin fragments produced.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18473123

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S11095-008-9606-3

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18473123

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/18473123

PubMed publication ID

18473123

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18473123

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/18473123

 

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