Effects of N-acetylcysteine plus mesalamine on prostaglandin synthesis and nitric oxide generation in TNBS-induced colitis in rats (Q46419373)

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English	Effects of N-acetylcysteine plus mesalamine on prostaglandin synthesis and nitric oxide generation in TNBS-induced colitis in rats	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

18716872

retrieved

22 December 2017

reference URL

http://europepmc.org/abstract/MED/18716872

title

Effects of N-acetylcysteine plus mesalamine on prostaglandin synthesis and nitric oxide generation in TNBS-induced colitis in rats (English)

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Europe PubMed Central

PubMed publication ID

18716872

retrieved

22 December 2017

reference URL

http://europepmc.org/abstract/MED/18716872

main subject

acetylcysteine

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author name string

Hanumantha R Ancha

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1

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Europe PubMed Central

PubMed publication ID

18716872

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22 December 2017

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http://europepmc.org/abstract/MED/18716872

Ravi R Kurella

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2

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Europe PubMed Central

PubMed publication ID

18716872

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22 December 2017

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http://europepmc.org/abstract/MED/18716872

Christine C McKimmey

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3

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Europe PubMed Central

PubMed publication ID

18716872

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22 December 2017

reference URL

http://europepmc.org/abstract/MED/18716872

Stanley Lightfoot

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4

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Europe PubMed Central

PubMed publication ID

18716872

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22 December 2017

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http://europepmc.org/abstract/MED/18716872

Richard F Harty

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5

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Europe PubMed Central

PubMed publication ID

18716872

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22 December 2017

reference URL

http://europepmc.org/abstract/MED/18716872

publication date

21 August 2008

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Europe PubMed Central

PubMed publication ID

18716872

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22 December 2017

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http://europepmc.org/abstract/MED/18716872

published in

Digestive Diseases and Sciences

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Europe PubMed Central

PubMed publication ID

18716872

retrieved

22 December 2017

reference URL

http://europepmc.org/abstract/MED/18716872

volume

54

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Europe PubMed Central

PubMed publication ID

18716872

retrieved

22 December 2017

reference URL

http://europepmc.org/abstract/MED/18716872

issue

4

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Europe PubMed Central

PubMed publication ID

18716872

retrieved

22 December 2017

reference URL

http://europepmc.org/abstract/MED/18716872

page(s)

758-766

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Europe PubMed Central

PubMed publication ID

18716872

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22 December 2017

reference URL

http://europepmc.org/abstract/MED/18716872

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Replenishment of glutathione levels improves mucosal function in experimental acute colitis

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Oxidative stress augments the production of matrix metalloproteinase-1, cyclooxygenase-2, and prostaglandin E2 through enhancement of NF-kappa B activity in lipopolysaccharide-activated human primary monocytes

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21 January 2018

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The metabolic effects of inhibitors of 5-lipoxygenase and of cyclooxygenase 1 and 2 are an advancement in the efficacy and safety of anti-inflammatory therapy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18716872

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12 December 2020

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Treatment of inflammatory diseases by selective eicosanoid inhibition: a double-edged sword?

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18716872

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12 December 2020

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Role of prostaglandins in ulcerative colitis. Enhanced production during active disease and inhibition by sulfasalazine

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18716872

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12 December 2020

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Inhibition of prostaglandin biosynthesis by sulphasalazine and its metabolites

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https://pubmed.ncbi.nlm.nih.gov/18716872

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12 December 2020

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12 December 2020

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Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: Role in proliferation and apoptosis in the intestine.

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12 December 2020

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Intestinal oxidative damage in inflammatory bowel disease: semi-quantification, localization, and association with mucosal antioxidants

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18716872

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12 December 2020

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Role of inducible nitric oxide synthase in trinitrobenzene sulphonic acid induced colitis in mice.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18716872

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12 December 2020

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Cyclooxygenase 2 is induced in colonic epithelial cells in inflammatory bowel disease

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18716872

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of blood- and tissue-associated inducible nitric-oxide synthase in colonic inflammation

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18716872

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The proinflammatory effect of prostaglandin E2 in experimental inflammatory bowel disease is mediated through the IL-23-->IL-17 axis

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18716872

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental colitis is ameliorated by inhibition of nitric oxide synthase activity

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18716872

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced synthesis of leukotriene B4 by colonic mucosa in inflammatory bowel disease

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18716872

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12 December 2020

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Exacerbation of inflammation-associated colonic injury in rat through inhibition of cyclooxygenase-2.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18716872

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12 December 2020

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Healing impairment effect of cyclooxygenase inhibitors on dextran sulfate sodium-induced colitis in rats

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18716872

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mesalazine inhibits activation of transcription factor NF-kappaB in inflamed mucosa of patients with ulcerative colitis

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18716872

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antioxidant therapy with N-acetylcysteine plus mesalamine accelerates mucosal healing in a rodent model of colitis

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18716872

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local production of chemokines and prostaglandin E2 in the acute, chronic and recovery phase of murine experimental colitis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18716872

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12 December 2020

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inferred from PubMed ID database lookup

Non-stop progress in inflammatory bowel disease: new players, new understanding, new therapies

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18716872

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of reactive oxygen metabolites in experimental colitis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18716872

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical evidence supporting the radical scavenger mechanism of 5-aminosalicylic acid

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18716872

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor-alpha antibody for induction of remission in Crohn's disease

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18716872

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12 December 2020

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Prostaglandins and epithelial response to injury

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18716872

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

alpha-Phenyl-N-tert-butylnitrone provides protection from dextran sulfate sodium-induced colitis in mice

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18716872

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-17 and lipopolysaccharides synergistically induce cyclooxygenase-2 expression in human intestinal myofibroblasts.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18716872

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progress in understanding the mechanisms of action of 5-aminosalicylic acid

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18716872

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects and mechanism of the selective COX-2 inhibitor, celecoxib, on rat colitis induced by trinitrobenzene sulfonic acid

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18716872

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Using COX-2 inhibitors in IBD: anti-inflammatories inflame a controversy

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18716872

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A distinct subset of chemokines dominates the mucosal chemokine response in inflammatory bowel disease.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18716872

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-inflammatory drugs: new multitarget compounds to face an old problem. The dual inhibition concept.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18716872

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of murine intestinal inflammation by reactive metabolites of oxygen and nitrogen: divergent roles of superoxide and nitric oxide

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18716872

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidants and free radicals in inflammatory bowel disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18716872

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S10620-008-0438-0

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18716872

retrieved

22 December 2017

reference URL

http://europepmc.org/abstract/MED/18716872

PubMed publication ID

18716872

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18716872

retrieved

22 December 2017

reference URL

http://europepmc.org/abstract/MED/18716872

 

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