The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88. (Q46367336)

21 December 2017

title

The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88. (English)

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21 December 2017

main subject

toll-like receptor

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alcoholic liver disease

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Istvan Hritz

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Pranoti Mandrekar

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21 December 2017

Arumugam Velayudham

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21 December 2017

Donna Catalano

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21 December 2017

Angela Dolganiuc

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21 December 2017

Karen Kodys

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21 December 2017

Evelyn Kurt-Jones

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21 December 2017

Gyongyi Szabo

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21 December 2017

language of work or name

English

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publication date

1 October 2008

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21 December 2017

published in

Hepatology

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21 December 2017

volume

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21 December 2017

issue

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21 December 2017

page(s)

1224-1231

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21 December 2017

Activation of the innate immune system and alcoholic liver disease: effects of ethanol per se or enhanced intestinal translocation of bacterial toxins induced by ethanol?

cites work

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Essential role of tumor necrosis factor alpha in alcohol-induced liver injury in mice

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NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease

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Cutting edge: direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-kappa B

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Cross-talk between IRAK-4 and the NADPH oxidase.

21 January 2018

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21 January 2018

TLR signaling pathways

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Kupffer cell activation by lipopolysaccharide in rats: role for lipopolysaccharide binding protein and toll-like receptor 4

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Role of lipopolysaccharide-binding protein in early alcohol-induced liver injury in mice

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Reduced early alcohol-induced liver injury in CD14-deficient mice

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Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice

21 January 2018

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Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4

21 January 2018

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Diverse regulation of NF-kappaB and peroxisome proliferator-activated receptors in murine nonalcoholic fatty liver.

21 January 2018

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Genes or environment to determine alcoholic liver disease and non-alcoholic fatty liver disease

21 January 2018

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Gene expression in the liver of rats fed alcohol by means of intragastric infusion

21 January 2018

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Hepatic expression of candidate genes in patients with alcoholic hepatitis: correlation with disease severity.

21 January 2018

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Increased lipopolysaccharide sensitivity in alcoholic fatty livers is independent of leptin deficiency and toll-like receptor 4 (TLR4) or TLR2 mRNA expression

21 January 2018

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Chronic ethanol feeding increases activation of NADPH oxidase by lipopolysaccharide in rat Kupffer cells: role of increased reactive oxygen in LPS-stimulated ERK1/2 activation and TNF-alpha production

21 January 2018

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Structure and regulation of the neutrophil respiratory burst oxidase: comparison with nonphagocyte oxidases

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NADPH oxidases: not just for leukocytes anymore!

21 January 2018

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NADPH oxidase in the liver: defensive, offensive, or fibrogenic?

21 January 2018

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Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5

21 January 2018

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The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

21 January 2018

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Role of endotoxin in NF-kappaB activation by ethanol in rat hepatocytes

21 January 2018

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MyD88-dependent and MyD88-independent pathways in synergy, priming, and tolerance between TLR agonists

21 January 2018

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CD14 is required for MyD88-independent LPS signaling.

21 January 2018

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Inducible nitric oxide synthase is required in alcohol-induced liver injury: studies with knockout mice

21 January 2018

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Early growth response-1 transcription factor is essential for ethanol-induced fatty liver injury in mice.

21 January 2018

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Nox2 and Rac1 regulate H2O2-dependent recruitment of TRAF6 to endosomal interleukin-1 receptor complexes

21 January 2018

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Cutting edge: MyD88 controls phagocyte NADPH oxidase function and killing of gram-negative bacteria.

21 January 2018

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Cooperation of STAT-1 and IRF-1 in interferon-gamma-induced transcription of the gp91(phox) gene

21 January 2018

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Activation of NADPH oxidase by transforming growth factor-beta in hepatocytes mediates up-regulation of epidermal growth factor receptor ligands through a nuclear factor-kappaB-dependent mechanism

21 January 2018

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Enhancement by pyrazole of lipopolysaccharide-induced liver injury in mice: role of cytochrome P450 2E1 and 2A5

21 January 2018

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12 December 2020

Endotoxin and Kupffer cell activation in alcoholic liver disease

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12 December 2020

Interferon regulatory factor-2 directs transcription from the gp91phox promoter

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12 December 2020

Chronic ethanol-mediated decrease in cAMP primes macrophages to enhanced LPS-inducible NF-kappaB activity and TNF expression: relevance to alcoholic liver disease

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12 December 2020

The regulation of cytochrome P450 2E1 during LPS-induced inflammation in the rat

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12 December 2020

Glucose transporter expression in brain. cDNA sequence of mouse GLUT3, the brain facilitative glucose transporter isoform, and identification of sites of expression by in situ hybridization

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12 December 2020

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12 December 2020

Identifiers

DOI

10.1002/HEP.22470

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21 December 2017

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21 December 2017