Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors. (Q46079015)

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24 January 2020

title

Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors (English)

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24 January 2020

Stephen Douglas Robinson

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24 January 2020

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24 January 2020

Kairbaan Hodivala-Dilke

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24 January 2020

Andrew R Reynolds

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24 January 2020

Ian R Hart

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24 January 2020

Alan R Watson

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24 January 2020

Rita G Silva

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24 January 2020

Georges Da Violante

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24 January 2020

Morgane Gourlaouen

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24 January 2020

Mishal Salih

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24 January 2020

Matt C Jones

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24 January 2020

Dylan T Jones

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24 January 2020

Garry Saunders

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24 January 2020

Françoise Perron-Sierra

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24 January 2020

Gordon C Tucker

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24 January 2020

language of work or name

English

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publication date

22 March 2009

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24 January 2020

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volume

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issue

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page(s)

392-400

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Rab-coupling protein coordinates recycling of alpha5beta1 integrin and EGFR1 to promote cell migration in 3D microenvironments.

24 January 2020

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Blockade of alpha v beta3 and alpha v beta5 integrins by RGD mimetics induces anoikis and not integrin-mediated death in human endothelial cells

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Regulators of endocytosis maintain localized receptor tyrosine kinase signaling in guided migration

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Rab11-family interacting protein 2 and myosin Vb are required for CXCR2 recycling and receptor-mediated chemotaxis

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Integrin signaling is critical for pathological angiogenesis

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alpha v-Integrin antagonist EMD 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin

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Antivascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis and growth of several mouse and human tumors

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The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis

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VEGF receptor signalling - in control of vascular function

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Manganese-induced integrin affinity maturation promotes recruitment of alpha V beta 3 integrin to focal adhesions in endothelial cells: evidence for a role of phosphatidylinositol 3-kinase and Src

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Vascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartments

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Preferential susceptibility of brain tumors to the antiangiogenic effects of an alpha(v) integrin antagonist

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Vascular endothelial growth factor-dependent down-regulation of Flk-1/KDR involves Cbl-mediated ubiquitination. Consequences on nitric oxide production from endothelial cells

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VEGF regulates the mobilization of VEGFR2/KDR from an intracellular endothelial storage compartment

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Endocytic transport of integrins during cell migration and invasion.

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In vivo therapy of malignant melanoma by means of antagonists of alphav integrins

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N-Methylated cyclic RGD peptides as highly active and selective alpha(V)beta(3) integrin antagonists

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A randomized multi-center phase II trial of the angiogenesis inhibitor Cilengitide (EMD 121974) and gemcitabine compared with gemcitabine alone in advanced unresectable pancreatic cancer

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In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts

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PDGF-regulated rab4-dependent recycling of alphavbeta3 integrin from early endosomes is necessary for cell adhesion and spreading

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alphavbeta3 integrin and angiogenesis: a moody integrin in a changing environment.

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12 December 2020

Elevated Flk1 (vascular endothelial growth factor receptor 2) signaling mediates enhanced angiogenesis in beta3-integrin-deficient mice

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12 December 2020

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12 December 2020

alphav beta 3 and alphav beta 5 integrin antagonists inhibit angiogenesis in vitro.

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12 December 2020

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12 December 2020