Stem cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development. (Q46032507)

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31 March 2020

title

Stem cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development (English)

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

A Kathuria

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31 March 2020

P Nowosiad

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R Jagasia

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31 March 2020

R D Taylor

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W Lucchesi

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language of work or name

English

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publication date

26 September 2017

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volume

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issue

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page(s)

735-746

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Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International

31 March 2020

start time

26 September 2017

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April 2022 Public Data File from Crossref

copyrighted

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cites work

Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice

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SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients

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Shank3 deficiency induces NMDA receptor hypofunction via an actin-dependent mechanism

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SHANK3 haploinsufficiency: a "common" but underdiagnosed highly penetrant monogenic cause of autism spectrum disorders

24 May 2018

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Modeling autism by SHANK gene mutations in mice

24 May 2018

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24 May 2018

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24 May 2018

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SHANK3 as an autism spectrum disorder-associated gene

24 May 2018

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24 May 2018

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Reduced excitatory neurotransmission and mild autism-relevant phenotypes in adolescent Shank3 null mutant mice

24 May 2018

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Modeling psychiatric disorders at the cellular and network levels

24 May 2018

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24 May 2018

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Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism

24 May 2018

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24 May 2018

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24 May 2018

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24 May 2018

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Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

24 May 2018

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24 May 2018

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Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

24 May 2018

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Etiological heterogeneity in autism spectrum disorders: More than 100 genetic and genomic disorders and still counting

24 May 2018

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A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells

24 May 2018

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From nose to brain: development of gonadotrophin-releasing hormone-1 neurones

24 May 2018

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A synaptic trek to autism

24 May 2018

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Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons

24 May 2018

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Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

24 May 2018

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Learning and memory and synaptic plasticity are impaired in a mouse model of Rett syndrome

24 May 2018

1 reference

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Identification of a recurrent breakpoint within the SHANK3 gene in the 22q13.3 deletion syndrome

24 May 2018

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Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome

24 May 2018

1 reference

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Postsynaptic shank antagonizes dendrite branching induced by the leucine-rich repeat protein Densin-180

24 May 2018

1 reference

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MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions

24 May 2018

1 reference

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Autism and abnormal development of brain connectivity.

24 May 2018

1 reference

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ProSAP/Shank proteins - a family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological disease

24 May 2018

1 reference

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Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: a quantitative examination.

24 May 2018

1 reference

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The Shank family of scaffold proteins

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5822449

Proteins of the ADF/cofilin family: essential regulators of actin dynamics

24 May 2018

1 reference

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Characterization of the Shank family of synaptic proteins. Multiple genes, alternative splicing, and differential expression in brain and development

24 May 2018

1 reference

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Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin

24 May 2018

1 reference

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Actin filament severing by cofilin dismantles actin patches and produces mother filaments for new patches

24 May 2018

1 reference

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The spatio-temporal expression of ProSAP/shank family members and their interaction partner LAPSER1 during Xenopus laevis development.

15 August 2018

1 reference

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Changes in the developmental trajectories of striatum in autism

15 August 2018

1 reference

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MeCP2-dependent transcriptional repression regulates excitatory neurotransmission

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5822449

Striatal volume on magnetic resonance imaging and repetitive behaviors in autism

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5822449

Pervasive neuroanatomic abnormalities of the brain in three cases of Rett's syndrome

15 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FMP.2017.185

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/MP.2017.185

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28948968%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28948968%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

PubMed publication ID

28948968

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28948968%20AND%20SRC:MED&resulttype=core&format=json