Homocysteine down-regulates cellular glutathione peroxidase (GPx1) by decreasing translation (Q45285244)

11 December 2017

title

Homocysteine down-regulates cellular glutathione peroxidase (GPx1) by decreasing translation (English)

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11 December 2017

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Joseph Loscalzo

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11 December 2017

Diane E Handy

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11 December 2017

Yufeng Zhang

series ordinal

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11 December 2017

language of work or name

English

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publication date

25 February 2005

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Journal of Biological Chemistry

11 December 2017

published in

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11 December 2017

volume

280

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11 December 2017

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11 December 2017

page(s)

15518-15525

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Hyperhomocysteinemia and its role in the development of atherosclerosis

11 December 2017

cites work

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Overexpression of cellular glutathione peroxidase rescues homocyst(e)ine-induced endothelial dysfunction

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Cellular redox state and endothelial dysfunction in mildly hyperhomocysteinemic cystathionine beta-synthase-deficient mice

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Characterization of mammalian selenoproteomes.

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Selenium regulation of glutathione peroxidase in human hepatoma cell line Hep3B.

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Mechanism and regulation of selenoprotein synthesis

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Protein factors mediating selenoprotein synthesis

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An RNA-binding protein recognizes a mammalian selenocysteine insertion sequence element required for cotranslational incorporation of selenocysteine

21 January 2018

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Homocysteine export from cells cultured in the presence of physiological or superfluous levels of methionine: methionine loading of non-transformed, transformed, proliferating, and quiescent cells in culture

21 January 2018

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Two distinct SECIS structures capable of directing selenocysteine incorporation in eukaryotes

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Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model

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Dietary supplementation with methionine and homocysteine promotes early atherosclerosis but not plaque rupture in ApoE-deficient mice

21 January 2018

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Hyperhomocysteinemia accelerates atherosclerosis in cystathionine beta-synthase and apolipoprotein E double knock-out mice with and without dietary perturbation

21 January 2018

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Facts and recommendations about total homocysteine determinations: an expert opinion

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Transcriptional activation of the human glutathione peroxidase promoter by p53.

21 January 2018

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Stability of gastrointestinal glutathione peroxidase mRNA in selenium deficiency depends on its 3'UTR.

21 January 2018

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3'UTRs of glutathione peroxidases differentially affect selenium-dependent mRNA stability and selenocysteine incorporation efficiency

21 January 2018

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AU-rich elements: characterization and importance in mRNA degradation

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Regulation of human thioredoxin reductase expression and activity by 3'-untranslated region selenocysteine insertion sequence and mRNA instability elements

21 January 2018

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A nuclear translation-like factor eIF4AIII is recruited to the mRNA during splicing and functions in nonsense-mediated decay

21 January 2018

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Selenium deficiency reduces the abundance of mRNA for Se-dependent glutathione peroxidase 1 by a UGA-dependent mechanism likely to be nonsense codon-mediated decay of cytoplasmic mRNA.

21 January 2018

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Selenocysteine codons decrease polysome association on endogenous selenoprotein mRNAs

21 January 2018

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Selenocysteine insertion or termination: factors affecting UGA codon fate and complementary anticodon:codon mutations

21 January 2018

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Efficiency of mammalian selenocysteine incorporation

21 January 2018

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Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways

21 January 2018

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A trip to the ER: coping with stress

21 January 2018

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Coupled tRNA(Sec)-dependent assembly of the selenocysteine decoding apparatus

21 January 2018

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Purification, Redox Sensitivity, and RNA Binding Properties of SECIS-binding Protein 2, a Protein Involved in Selenoprotein Biosynthesis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M501452200

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11 December 2017

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