Patients with chronic mucocutaneous candidiasis exhibit reduced production of Th17-associated cytokines IL-17 and IL-22. (Q45239424)

11 December 2017

title

Patients with chronic mucocutaneous candidiasis exhibit reduced production of Th17-associated cytokines IL-17 and IL-22. (English)

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chronic mucocutaneous candidiasis

11 December 2017

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author

Claudia Traidl-Hoffmann

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11 December 2017

Kilian Eyerich

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11 December 2017

Stefanie Foerster

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11 December 2017

Stephanie Rombold

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11 December 2017

Hans-Peter Seidl

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11 December 2017

Heidrun Behrendt

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11 December 2017

Heidelore Hofmann

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11 December 2017

Johannes Ring

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11 December 2017

language of work or name

English

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publication date

10 July 2008

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Journal of Investigative Dermatology

11 December 2017

published in

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11 December 2017

volume

128

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11 December 2017

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11 December 2017

page(s)

2640-2645

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Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells

11 December 2017

cites work

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Phenotypic and functional features of human Th17 cells

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Both CD4+ and CD8+ lymphocytes reduce the severity of tissue lesions in murine systemic cadidiasis, and CD4+ cells also demonstrate strain-specific immunopathological effects

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An immune defect causing dominant chronic mucocutaneous candidiasis and thyroid disease maps to chromosome 2p in a single family

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IL-10 subfamily members: IL-19, IL-20, IL-22, IL-24 and IL-26.

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7 January 2021

Characterization of the cellular immune function of patients with chronic mucocutaneous candidiasis

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7 January 2021

Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes.

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7 January 2021

Altered, but not diminished specific T cell response in chronic mucocutaneous candidiasis patients

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7 January 2021

Human beta-defensins: differential activity against candidal species and regulation by Candida albicans

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Expanding the effector CD4 T-cell repertoire: the Th17 lineage.

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7 January 2021

Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice

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7 January 2021

Chronic mucocutaneous candidiasis

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7 January 2021

IL-22 is expressed by Th17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis

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7 January 2021

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17

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7 January 2021

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

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7 January 2021

Deregulated Production of Protective Cytokines in Response toCandida albicansInfection in Patients with Chronic Mucocutaneous Candidiasis

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7 January 2021

Defective antifungal T-helper 1 (TH1) immunity in a murine model of allogeneic T-cell-depleted bone marrow transplantation and its restoration by treatment with TH2 cytokine antagonists.

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7 January 2021

Human T cells that are able to produce IL-17 express the chemokine receptor CCR6.

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7 January 2021

Increased resistance to systemic candidiasis in athymic or interleukin-10-depleted mice

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7 January 2021

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

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7 January 2021

Human beta-defensins kill Candida albicans in an energy-dependent and salt-sensitive manner without causing membrane disruption

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7 January 2021

Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R

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7 January 2021

Identifiers

DOI

10.1038/JID.2008.139

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Dimensions Publication ID

11 December 2017

1052314540

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