Levels of 4-1BB transcripts and soluble 4-1BB protein are elevated in the adipose tissue of human obese subjects and are associated with inflammatory and metabolic parameters. (Q45170299)

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scientific article published on 27 November 2013

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English	Levels of 4-1BB transcripts and soluble 4-1BB protein are elevated in the adipose tissue of human obese subjects and are associated with inflammatory and metabolic parameters.	scientific article published on 27 November 2013

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1 March 2020

Levels of 4-1BB transcripts and soluble 4-1BB protein are elevated in the adipose tissue of human obese subjects and are associated with inflammatory and metabolic parameters (English)

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1 March 2020

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Il Seong Nam-Goong

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T H Tu

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C-S Kim

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J-H Kang

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C W Nam

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E S Kim

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Y I Kim

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J I Choi

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T Kawada

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1 March 2020

J H Yoon Park

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M-S Choi

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R Yu

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27 November 2013

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1 March 2020

International Journal of Obesity

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1 March 2020

38

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8

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1 March 2020

1075-1082

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1 March 2020

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance

1 reference

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Adipocytokines and the metabolic complications of obesity

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21 January 2018

Obesity, Metabolic Syndrome, and Cardiovascular Disease

1 reference

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The inflammatory syndrome: the role of adipose tissue cytokines in metabolic disorders linked to obesity

1 reference

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Obesity is associated with macrophage accumulation in adipose tissue

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2013.222

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Inflammation and insulin resistance

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A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha

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The inflammatory receptor CD40 is expressed on human adipocytes: contribution to crosstalk between lymphocytes and adipocytes.

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Characterization of herpes virus entry mediator as a factor linked to obesity

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CD40-CD40L: linking pancreatic, adipose tissue and vascular inflammation in type 2 diabetes and its complications

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Effects of obesity and weight loss on soluble CD40L levels

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CD137-deficient mice have reduced NK/NKT cell numbers and function, are resistant to lipopolysaccharide-induced shock syndromes, and have lower IL-4 responses

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https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

Deficiency for costimulatory receptor 4-1BB protects against obesity-induced inflammation and metabolic disorders

1 reference

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21 January 2018

CD137 ligand, a member of the tumor necrosis factor family, regulates immune responses via reverse signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

CD137 (4-1BB) deficiency reduces atherosclerosis in hyperlipidemic mice.

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

Blocking 4-1BB/4-1BB ligand interactions prevents herpetic stromal keratitis.

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

CD137-CD137 Ligand Interactions in Inflammation

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

Serum concentrations of soluble 4-1BB and 4-1BB ligand correlated with the disease severity in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

Positive correlation between CD137 expression and complex stenosis morphology in patients with acute coronary syndromes.

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

Clinical implications of elevated serum soluble CD137 levels in patients with acute coronary syndrome

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; Internat

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

Metabolic syndrome--a new world-wide definition. A Consensus Statement from the International Diabetes Federation

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https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

The soluble interleukin 6 receptor: mechanisms of production and implications in disease

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

Induction of lethal graft-versus-host disease by anti-CD137 monoclonal antibody in mice prone to chronic graft-versus-host disease

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

Plasma soluble tumour necrosis factor-alpha receptor 2 is elevated in obesity: specific contribution of visceral adiposity

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

IL-6 and its receptors in coronary artery disease and acute myocardial infarction

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

Soluble CD137 (4-1BB) ligand is released following leukocyte activation and is found in sera of patients with hematological malignancies.

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

Interleukin 6 and its Receptor: Ten Years Later

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https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

The metabolic syndrome in the asian population

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

Levels of soluble CD137 are enhanced in sera of leukemia and lymphoma patients and are strongly associated with chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2013.222

21 January 2018

T-ing up inflammation in fat

1 reference

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Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge

1 reference

https://pubmed.ncbi.nlm.nih.gov/24281650

12 December 2020

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CD40L induces inflammation and adipogenesis in adipose cells--a potential link between metabolic and cardiovascular disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24281650

12 December 2020

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Admission levels of soluble CD137 are increased in patients with acute pancreatitis and are associated with subsequent complications

1 reference

https://pubmed.ncbi.nlm.nih.gov/24281650

12 December 2020

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Canadian global village reality: anthropometric surrogate cutoffs and metabolic abnormalities among Canadians of East Asian, South Asian, and European descent

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CD137 ligand reverse signaling has multiple functions in human dendritic cells during an adaptive immune response

1 reference

https://pubmed.ncbi.nlm.nih.gov/24281650

12 December 2020

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LIGHT/TNFSF14 enhances adipose tissue inflammatory responses through its interaction with HVEM

1 reference

https://pubmed.ncbi.nlm.nih.gov/24281650

12 December 2020

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Enhanced levels of soluble and membrane-bound CD137 levels in patients with acute coronary syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24281650

12 December 2020

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Heightened intrathecal release of soluble CD137 in patients with multiple sclerosis

1 reference

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12 December 2020

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A soluble form of CD137 (ILA/4-1BB), a member of the TNF receptor family, is released by activated lymphocytes and is detectable in sera of patients with rheumatoid arthritis

1 reference

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12 December 2020

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ICAM-1 expression in adipose tissue: effects of diet-induced obesity in mice

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4-1BB engagement costimulates NKT cell activation and exacerbates NKT cell ligand-induced airway hyperresponsiveness and inflammation

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1 reference

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Identifiers

10.1038/IJO.2013.222

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1 March 2020

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1 March 2020

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