Focal adhesion kinase is required for KSHV vGPCR signaling (Q44963160)

7 December 2017

title

Focal adhesion kinase is required for KSHV vGPCR signaling (English)

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G protein-coupled receptor

7 December 2017

main subject

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author name string

Meilan He

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7 December 2017

Thomas Bakken

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7 December 2017

Alia Kassimova

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7 December 2017

Chris Boshoff

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7 December 2017

Nicola Philpott

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7 December 2017

Mark L Cannon

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7 December 2017

publication date

2 May 2011

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7 December 2017

published in

Molecular Carcinogenesis

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7 December 2017

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7 December 2017

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7 December 2017

page(s)

339-351

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Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma

7 December 2017

cites work

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Detection of Kaposi sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi's sarcoma

21 January 2018

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Kaposi's sarcoma-associated herpesvirus and Kaposi's sarcoma in Africa. Uganda Kaposi's Sarcoma Study Group

21 January 2018

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Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas

21 January 2018

1 reference

Characterization of the murine gammaherpesvirus 68 ORF74 product: a novel oncogenic G protein-coupled receptor

21 January 2018

1 reference

Human herpesvirus KSHV encodes a constitutively active G-protein-coupled receptor linked to cell proliferation

21 January 2018

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Characterization of a chemokine receptor-related gene in human herpesvirus 8 and its expression in Kaposi's sarcoma

21 January 2018

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Transgenic expression of the chemokine receptor encoded by human herpesvirus 8 induces an angioproliferative disease resembling Kaposi's sarcoma

21 January 2018

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Kaposi's sarcoma-like tumors in a human herpesvirus 8 ORF74 transgenic mouse

21 January 2018

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The human herpes virus 8-encoded chemokine receptor is required for angioproliferation in a murine model of Kaposi's sarcoma

21 January 2018

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Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor signals through multiple pathways in endothelial cells

21 January 2018

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Activation of NF-kappaB by the human herpesvirus 8 chemokine receptor ORF74: evidence for a paracrine model of Kaposi's sarcoma pathogenesis

21 January 2018

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G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator

21 January 2018

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The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor has broad signaling effects in primary effusion lymphoma cells

21 January 2018

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Kaposi's sarcoma-associated herpesvirus-encoded G protein-coupled receptor ORF74 constitutively activates p44/p42 MAPK and Akt via G(i) and phospholipase C-dependent signaling pathways

21 January 2018

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The KSHV G protein-coupled receptor signals via multiple pathways to induce transcription factor activation in primary effusion lymphoma cells

21 January 2018

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The role of focal-adhesion kinase in cancer - a new therapeutic opportunity

21 January 2018

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Signal transduction by focal adhesion kinase in cancer

21 January 2018

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Therapeutic efficacy of a novel focal adhesion kinase inhibitor TAE226 in ovarian carcinoma

21 January 2018

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Inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo

21 January 2018

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Focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer

21 January 2018

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Focal adhesion kinase expression in oral cancers

21 January 2018

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The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. Involvement of death receptor-related signaling pathways.

21 January 2018

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Overexpression of focal adhesion kinase, a protein tyrosine kinase, in ovarian carcinoma.

21 January 2018

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Focal adhesion kinase is critical for entry of Kaposi's sarcoma-associated herpesvirus into target cells

21 January 2018

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Origins of circulating endothelial cells and endothelial outgrowth from blood

21 January 2018

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In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

21 January 2018

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Identification of p130Cas as a Mediator of Focal Adhesion Kinase–promoted Cell Migration

21 January 2018

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CXCL8-induced FAK phosphorylation via CXCR1 and CXCR2: cytoskeleton- and integrin-related mechanisms converge with FAK regulatory pathways in a receptor-specific manner

21 January 2018

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Selective expression of an endogenous inhibitor of FAK regulates proliferation and migration of vascular smooth muscle cells

21 January 2018

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Kaposi's sarcoma-associated herpesvirus latent gene vFLIP inhibits viral lytic replication through NF-kappaB-mediated suppression of the AP-1 pathway: a novel mechanism of virus control of latency

21 January 2018

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Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

21 January 2018

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Focal adhesion kinase mediates cell survival via NF-kappaB and ERK signaling pathways.

21 January 2018

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Peripheral blood endothelial progenitors as potential reservoirs of Kaposi's sarcoma-associated herpesvirus

21 January 2018

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Differential effects of shear stress and cyclic stretch on focal adhesion remodeling, site-specific FAK phosphorylation, and small GTPases in human lung endothelial cells

21 January 2018

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Focal adhesion kinase: the first ten years

21 January 2018

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p125FAK tyrosine phosphorylation and focal adhesion assembly: studies with phosphotyrosine phosphatase inhibitors.

21 January 2018

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Involvement of site-specific FAK phosphorylation in sphingosine-1 phosphate- and thrombin-induced focal adhesion remodeling: role of Src and GIT.

21 January 2018

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Disruption of epithelial cell-matrix interactions induces apoptosis

21 January 2018

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Control of adhesion-dependent cell survival by focal adhesion kinase

21 January 2018

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Agonists and inverse agonists for the herpesvirus 8-encoded constitutively active seven-transmembrane oncogene product, ORF-74

21 January 2018

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Tumor Necrosis Factor-induced Nuclear Factor κB Activation Is Impaired in Focal Adhesion Kinase-deficient Fibroblasts

21 January 2018

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Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60.

21 January 2018

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Angiogenic and HIV-inhibitory functions of KSHV-encoded chemokines

21 January 2018

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A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak

21 January 2018

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Degradation of p27(Kip) cdk inhibitor triggered by Kaposi's sarcoma virus cyclin-cdk6 complex

21 January 2018

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KSHV ORF K9 (vIRF) is an oncogene which inhibits the interferon signaling pathway

21 January 2018

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A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus.

21 January 2018

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Deregulated signal transduction by the K1 gene product of Kaposi's sarcoma-associated herpesvirus

21 January 2018

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Kaposi's sarcoma-associated human herpesvirus-8 encodes homologues of macrophage inflammatory protein-1 and interleukin-6.

21 January 2018

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Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

21 January 2018

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RBP-J (CSL) is essential for activation of the K14/vGPCR promoter of Kaposi's sarcoma-associated herpesvirus by the lytic switch protein RTA

21 January 2018

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Role of ORF74-encoded viral G protein-coupled receptor in human herpesvirus 8 lytic replication

21 January 2018

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Kaposi sarcoma-associated herpes virus (KSHV) G protein-coupled receptor (vGPCR) activates the ORF50 lytic switch promoter: a potential positive feedback loop for sustained ORF50 gene expression

21 January 2018

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KSHV G protein-coupled receptor inhibits lytic gene transcription in primary-effusion lymphoma cells via p21-mediated inhibition of Cdk2.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/MC.20790

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7 December 2017

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