Alternative splicing of a beta4 subunit proline-rich motif regulates voltage-dependent gating and toxin block of Cav2.1 Ca2+ channels. (Q44856248)

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scientific article published in November 2002

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English	Alternative splicing of a beta4 subunit proline-rich motif regulates voltage-dependent gating and toxin block of Cav2.1 Ca2+ channels.	scientific article published in November 2002

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Europe PubMed Central

PMC publication ID

6758066

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417658%20AND%20SRC:MED&resulttype=core&format=json

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14 December 2019

title

Alternative splicing of a beta4 subunit proline-rich motif regulates voltage-dependent gating and toxin block of Cav2.1 Ca2+ channels (English)

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Europe PubMed Central

PMC publication ID

6758066

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14 December 2019

main subject

alternative mRNA splicing, via spliceosome

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author name string

Thomas D Helton

series ordinal

1

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Europe PubMed Central

PMC publication ID

6758066

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417658%20AND%20SRC:MED&resulttype=core&format=json

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14 December 2019

Douglas J Kojetin

series ordinal

2

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Europe PubMed Central

PMC publication ID

6758066

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417658%20AND%20SRC:MED&resulttype=core&format=json

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14 December 2019

John Cavanagh

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3

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PMC publication ID

6758066

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417658%20AND%20SRC:MED&resulttype=core&format=json

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14 December 2019

William A Horne

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4

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Europe PubMed Central

PMC publication ID

6758066

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417658%20AND%20SRC:MED&resulttype=core&format=json

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14 December 2019

language of work or name

English

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publication date

1 November 2002

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Europe PubMed Central

PMC publication ID

6758066

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417658%20AND%20SRC:MED&resulttype=core&format=json

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14 December 2019

published in

Journal of Neuroscience

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Europe PubMed Central

PMC publication ID

6758066

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14 December 2019

volume

22

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Europe PubMed Central

PMC publication ID

6758066

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417658%20AND%20SRC:MED&resulttype=core&format=json

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14 December 2019

issue

21

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Europe PubMed Central

PMC publication ID

6758066

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14 December 2019

page(s)

9331-9339

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PMC publication ID

6758066

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14 December 2019

cites work

Structural elements in domain IV that influence biophysical and pharmacological properties of human alpha1A-containing high-voltage-activated calcium channels

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PubMed

reference URL

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12 December 2020

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Modelling of a voltage-dependent Ca2+ channel beta subunit as a basis for understanding its functional properties

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A new beta subtype-specific interaction in alpha1A subunit controls P/Q-type Ca2+ channel activation

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PubMed

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12 December 2020

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Structural rearrangements underlying K+-channel activation gating

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12 December 2020

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Signaling pathways are focused at specialized regions of the plasma membrane by scaffolding proteins of the MAGUK family

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PubMed

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12 December 2020

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Atomic scale movement of the voltage-sensing region in a potassium channel measured via spectroscopy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

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Spectroscopic mapping of voltage sensor movement in the Shaker potassium channel

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PubMed

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The importance of being proline: the interaction of proline-rich motifs in signaling proteins with their cognate domains

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https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

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The voltage sensor in voltage-dependent ion channels

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new twist in the saga of charge movement in voltage-dependent ion channels

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fast inactivation of voltage-dependent calcium channels. A hinged-lid mechanism?

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

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Syntaxin modulation of slow inactivation of N-type calcium channels.

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https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural basis for phosphoserine-proline recognition by group IV WW domains

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative protein structure modeling of genes and genomes

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta 1-adrenergic receptor association with PSD-95. Inhibition of receptor internalization and facilitation of beta 1-adrenergic receptor interaction with N-methyl-D-aspartate receptors

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and regulation of voltage-gated Ca2+ channels

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular determinants of the functional interaction between syntaxin and N-type Ca2+ channel gating

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PDZ domains: More than just a glue

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular determinants of inactivation within the I-II linker of alpha1E (CaV2.3) calcium channels

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NeW wrinkles for an old domain

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of gating mode by a single amino acid residue in transmembrane segment IS3 of the N-type Ca2+ channel

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino acids in segment IVS6 and beta-subunit interaction support distinct conformational changes during Ca(v)2.1 inactivation

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of inactivation determinants in the domain IIS6 region of high voltage-activated calcium channels.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Short-term synaptic plasticity as a temporal filter

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of the KcsA channel intracellular gate in the open state

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/12417658

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism and role of PDZ domains in signaling complex assembly

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular determinants of voltage-dependent slow inactivation of the Ca2+ channel

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterization of novel human Ca(v)2.2 (alpha 1B) calcium channel variants lacking the synaptic protein interaction site.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternative splicing of the beta 4 subunit has alpha1 subunit subtype-specific effects on Ca2+ channel gating

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

WW and SH3 domains, two different scaffolds to recognize proline-rich ligands

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure and mechanism of a calcium-gated potassium channel

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The open pore conformation of potassium channels

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of p/q-Ca2+ channels in metabotropic glutamate receptor 2/3-dependent presynaptic long-term depression at nucleus accumbens synapses.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An analysis of vertebrate mRNA sequences: intimations of translational control

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/12417658

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basic local alignment search tool

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium channel β-subunit binds to a conserved motif in the I–II cytoplasmic linker of the α1-subunit

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular diversity of Ca2+ channel alpha 1 subunits from the marine ray Discopyge ommata

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular determinants of voltage-dependent inactivation in calcium channels

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural determinants of the blockade of N-type calcium channels by a peptide neurotoxin

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative protein modelling by satisfaction of spatial restraints

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Verification of protein structures: patterns of nonbonded atomic interactions

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Main-chain bond lengths and bond angles in protein structures

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MOLMOL: a program for display and analysis of macromolecular structures

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic depression and cortical gain control

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of functionally distinct isoforms of the N-type Ca2+ channel in rat sympathetic ganglia and brain

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of neuroligins to PSD-95

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A beta 4 isoform-specific interaction site in the carboxyl-terminal region of the voltage-dependent Ca2+ channel alpha 1A subunit

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PDZ Motifs in PTP-BL and RIL Bind to Internal Protein Segments in the LIM Domain Protein RIL

1 reference

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reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

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based on heuristic

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The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

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PubMed

reference URL

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based on heuristic

inferred from PubMed ID database lookup

CRIPT, a novel postsynaptic protein that binds to the third PDZ domain of PSD-95/SAP90

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

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based on heuristic

inferred from PubMed ID database lookup

Inactivation of presynaptic calcium current contributes to synaptic depression at a fast central synapse.

1 reference

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https://pubmed.ncbi.nlm.nih.gov/12417658

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based on heuristic

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Preferential closed-state inactivation of neuronal calcium channels

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reference URL

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based on heuristic

inferred from PubMed ID database lookup

Citron binds to PSD-95 at glutamatergic synapses on inhibitory neurons in the hippocampus

1 reference

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reference URL

https://pubmed.ncbi.nlm.nih.gov/12417658

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12 December 2020

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Identifiers

DOI

10.1523/JNEUROSCI.22-21-09331.2002

1 reference

stated in

Europe PubMed Central

PMC publication ID

6758066

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417658%20AND%20SRC:MED&resulttype=core&format=json

retrieved

14 December 2019

PMC publication ID

6758066

1 reference

stated in

Europe PubMed Central

PMC publication ID

6758066

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417658%20AND%20SRC:MED&resulttype=core&format=json

retrieved

14 December 2019

PubMed publication ID

12417658

1 reference

stated in

Europe PubMed Central

PMC publication ID

6758066

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417658%20AND%20SRC:MED&resulttype=core&format=json

retrieved

14 December 2019

 

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