Acquisition of FLT3 or N-ras mutations is frequently associated with progression of myelodysplastic syndrome to acute myeloid leukemia (Q44737477)

5 December 2017

title

Acquisition of FLT3 or N-ras mutations is frequently associated with progression of myelodysplastic syndrome to acute myeloid leukemia (English)

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5 December 2017

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myelodysplastic syndrome

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Shih LY

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5 December 2017

Huang CF

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5 December 2017

Wang PN

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5 December 2017

Wu JH

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5 December 2017

Lin TL

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5 December 2017

Dunn P

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5 December 2017

Kuo MC

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5 December 2017

language of work or name

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1 March 2004

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5 December 2017

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5 December 2017

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5 December 2017

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5 December 2017

page(s)

466-475

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Clonal development of myeloproliferative disorders: clues to hematopoietic differentiation and multistep pathogenesis of cancer

5 December 2017

cites work

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2403274

RAS and leukemia: from basic mechanisms to gene-directed therapy

21 January 2018

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The molecular pathophysiology of myeloid leukaemias: Ras revisited.

21 January 2018

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Multiple point mutation of N-ras and K-ras oncogenes in myelodysplastic syndrome and acute myelogenous leukemia

21 January 2018

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RAS, FMS and p53 mutations and poor clinical outcome in myelodysplasias: a 10-year follow-up.

21 January 2018

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Correlation of N-ras point mutations with specific chromosomal abnormalities in primary myelodysplastic syndrome.

21 January 2018

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Cytogenetic analysis and RAS mutations in primary myelodysplastic syndromes

21 January 2018

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The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the Unite

21 January 2018

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Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis

21 January 2018

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Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

21 January 2018

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Identification of novel FLT-3 Asp835 mutations in adult acute myeloid leukaemia

21 January 2018

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Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease

21 January 2018

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Constitutive activation of FLT3 in acute myeloid leukaemia and its consequences for growth of 32D cells

21 January 2018

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Constitutive activation of FLT3 stimulates multiple intracellular signal transducers and results in transformation.

21 January 2018

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Proposals for the classification of the myelodysplastic syndromes

21 January 2018

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Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British Cooperative Group

21 January 2018

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Proposal for the recognition of minimally differentiated acute myeloid leukaemia (AML-MO)

21 January 2018

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FLT3-TKD mutation in childhood acute myeloid leukemia

21 January 2018

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Studies of FLT3 mutations in paired presentation and relapse samples from patients with acute myeloid leukemia: implications for the role of FLT3 mutations in leukemogenesis, minimal residual disease detection, and possible therapy with FLT3 inhibit

21 January 2018

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The roles of FLT3 in hematopoiesis and leukemia

21 January 2018

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Cytogenetic studies, ras mutation, and clinical characteristics in primary myelodysplastic syndrome. A study on 68 Chinese patients in Taiwan

21 January 2018

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7 January 2021

N-ras mutations: Incidence and clinical relevance in myelodysplastic syndrome and acute myelogenous leukemia

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7 January 2021

No concomitant occurrence of the N-ras and p53 gene mutations in myelodysplastic syndromes

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2403274

7 January 2021

Codon 12 ras mutations in patients with myelodysplastic syndrome: incidence and prognostic value

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7 January 2021

Biological characteristics and prognosis of adult acute myeloid leukemia with internal tandem duplications in the Flt3 gene

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7 January 2021

Tandem duplications of the FLT3 receptor gene are associated with leukemic transformation of myelodysplasia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2403274

7 January 2021

Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product

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7 January 2021

Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines

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7 January 2021

Molecular diagnosis of haematological disorders using DNA from stored bone marrow slides

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7 January 2021

Internal tandem duplication of FLT3 in relapsed acute myeloid leukemia: a comparative analysis of bone marrow samples from 108 adult patients at diagnosis and relapse

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2403274

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2403274

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5 December 2017

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