Decitabine induces cell cycle arrest at the G1 phase via p21(WAF1) and the G2/M phase via the p38 MAP kinase pathway (Q44512459)

3 December 2017

title

Decitabine induces cell cycle arrest at the G1 phase via p21(WAF1) and the G2/M phase via the p38 MAP kinase pathway (English)

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3 December 2017

Joseph DeSimone

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3 December 2017

Donald Lavelle

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3 December 2017

Maria Hankewych

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3 December 2017

Tatiana Kousnetzova

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3 December 2017

Yi-Hsiang Chen

series ordinal

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3 December 2017

publication date

1 November 2003

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3 December 2017

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3 December 2017

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3 December 2017

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3 December 2017

page(s)

999-1007

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Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

3 December 2017

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De novo methylation of tumor suppressor gene p16/INK4a is a frequent finding in multiple myeloma patients at diagnosis

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p16(INK4a) and p15(INK4b) gene methylations in plasma cells from monoclonal gammopathy of undetermined significance

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7 January 2021

Hypermethylation of a 5′ CpG island of p16 is a frequent event in non-Hodgkin’s lymphoma

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7 January 2021

Low-dose 5-aza-2'-deoxycytidine, a DNA hypomethylating agent, for the treatment of high-risk myelodysplastic syndrome: a multicenter phase II study in elderly patients

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7 January 2021

Cytogenetic responses in high-risk myelodysplastic syndrome following low-dose treatment with the DNA methylation inhibitor 5-aza-2'-deoxycytidine

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7 January 2021

Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B.

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7 January 2021

Activation of the p53 DNA damage response pathway after inhibition of DNA methyltransferase by 5-aza-2'-deoxycytidine.

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7 January 2021

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

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7 January 2021

Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase

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7 January 2021

Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest

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7 January 2021

Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment

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7 January 2021

The p21(WAF1/CIP1) promoter is methylated in Rat-1 cells: stable restoration of p53-dependent p21(WAF1/CIP1) expression after transfection of a genomic clone containing the p21(WAF1/CIP1) gene

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7 January 2021

Histone deacetylase inhibitors increase p21(WAF1) and induce apoptosis of human myeloma cell lines independent of decreased IL-6 receptor expression

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7 January 2021

Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation

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7 January 2021

Suppression of intestinal neoplasia by DNA hypomethylation.

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5-Aza-2'-deoxycytidine is chemopreventive in a 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone-induced primary mouse lung tumor model

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7 January 2021

10.1016/S0145-2126(03)00068-7

Identifiers

DOI

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3 December 2017

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