p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis (Q44426545)

2 December 2017

title

p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis (English)

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2 December 2017

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Daniele Bergamaschi

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2 December 2017

Milena Gasco

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2 December 2017

Louise Hiller

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2 December 2017

Alexandra Sullivan

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2 December 2017

Nelofer Syed

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2 December 2017

Giuseppe Trigiante

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2 December 2017

Isik Yulug

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2 December 2017

Marco Merlano

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2 December 2017

Gianmauro Numico

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2 December 2017

Alberto Comino

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2 December 2017

Marlene Attard

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2 December 2017

Olivier Reelfs

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2 December 2017

Barry Gusterson

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2 December 2017

Alexandra K Bell

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2 December 2017

Victoria Heath

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2 December 2017

Mahvash Tavassoli

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2 December 2017

Paul Smith

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2 December 2017

Xin Lu

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2 December 2017

Tim Crook

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2 December 2017

publication date

1 April 2003

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2 December 2017

page(s)

387-402

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Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

2 December 2017

cites work

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TP53 mutation is related to poor prognosis after radiotherapy, but not surgery, in squamous cell carcinoma of the head and neck

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7 January 2021

Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy

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E7 proteins from oncogenic human papillomavirus types transactivate p73: role in cervical intraepithelial neoplasia

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p53 alterations predict tumor response to neoadjuvant chemotherapy in head and neck squamous cell carcinoma: a prospective series.

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7 January 2021

Molecular alterations of p73 in human esophageal squamous cell carcinomas: loss of heterozygosity occurs frequently; loss of imprinting and elevation of p73 expression may be related to defective p53.

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DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes.

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Transcriptional activation by p53 correlates with suppression of growth but not transformation.

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7 January 2021

Two new p73 splice variants, gamma and delta, with different transcriptional activity.

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p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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Transactivation-deficient p73alpha (p73Deltaexon2) inhibits apoptosis and competes with p53.

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7 January 2021

Tumour stage, node stage, p53 gene status, and bcl-2 protein expression as predictors of tumour response to platin-fluorouracil chemotherapy in patients with squamous-cell carcinoma of the head and neck

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7 January 2021

A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain

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7 January 2021

Cumulative prognostic value of p53 mutations and bcl-2 protein expression in head-and-neck cancer treated by radiotherapy.

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7 January 2021

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

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7 January 2021

Role for the p53 homologue p73 in E2F-1-induced apoptosis

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7 January 2021

Chemosensitivity linked to p73 function

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7 January 2021

Apoptosis: a link between cancer genetics and chemotherapy

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Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo

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7 January 2021

Monoallelically Expressed Gene Related to p53 at 1p36, a Region Frequently Deleted in Neuroblastoma and Other Human Cancers

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7 January 2021

Nonparametric Estimation from Incomplete Observations

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7 January 2021

p53 mutation and locoregional treatment failure in head and neck squamous cell carcinoma

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7 January 2021

Mutant p53 protein expression interferes with p53-independent apoptotic pathways

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7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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7 January 2021

p53 status and the efficacy of cancer therapy in vivo

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7 January 2021

A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

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7 January 2021

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. analysis and examples

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7 January 2021

The p53 and mdm-2 genes in human testicular germ-cell tumors

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7 January 2021

Dissecting p53 tumor suppressor functions in vivo

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7 January 2021

Assessing TP53 status in human tumours to evaluate clinical outcome

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7 January 2021

Role of the p53-homologue p73 in E2F1-induced apoptosis

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7 January 2021

Physical and Functional Interaction between p53 Mutants and Different Isoforms of p73

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7 January 2021

Physical interaction with human tumor-derived p53 mutants inhibits p63 activities.

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7 January 2021

Inactivate the remaining p53 allele or the alternate p73? Preferential selection of the Arg72 polymorphism in cancers with recessive p53 mutants but not transdominant mutants

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7 January 2021

Surfing the p53 network

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7 January 2021

Live or let die: the cell's response to p53

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7 January 2021

Specific p53 mutations predict poor prognosis in oral squamous cell carcinoma

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7 January 2021

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

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7 January 2021

DeltaNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors

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7 January 2021

10.1016/S1535-6108(03)00079-5

Identifiers

DOI

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2 December 2017

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