Pathways accessory to proteasomal proteolysis are less efficient in major histocompatibility complex class I antigen production (Q44253376)

1 December 2017

title

Pathways accessory to proteasomal proteolysis are less efficient in major histocompatibility complex class I antigen production (English)

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Nico P Dantuma

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Herman S Overkleeft

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Matthew Bogyo

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1 December 2017

Hidde Ploegh

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1 December 2017

Xu Hong

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1 December 2017

Jelena Petrovic

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1 December 2017

Anna Borodovsky

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1 December 2017

Rickard Glas

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1 December 2017

language of work or name

English

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publication date

16 December 2002

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Journal of Biological Chemistry

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inferred from page(s)

published in

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volume

278

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1 December 2017

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1 December 2017

page(s)

10013-10021

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Degradation of cell proteins and the generation of MHC class I-presented peptides

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cites work

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https://api.crossref.org/works/10.1074%2FJBC.M211221200

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The role of tricorn protease and its aminopeptidase-interacting factors in cellular protein degradation

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Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase

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Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses

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Immunoproteasomes shape immunodominance hierarchies of antiviral CD8(+) T cells at the levels of T cell repertoire and presentation of viral antigens.

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Integration of the ubiquitin-proteasome pathway with a cytosolic oligopeptidase activity

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Tripeptidyl peptidases: enzymes that count

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Covalent modification of the active site threonine of proteasomal beta subunits and the Escherichia coli homolog HslV by a new class of inhibitors

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Extended peptide-based inhibitors efficiently target the proteasome and reveal overlapping specificities of the catalytic beta-subunits

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Peptide influences the folding and intracellular transport of free major histocompatibility complex class I heavy chains

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Differences in the expression of human class I MHC alleles and their associated peptides in the presence of proteasome inhibitors

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Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

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Empty MHC class I molecules come out in the cold

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Identification of a novel tumor-specific CTL epitope presented by RMA, EL-4, and MBL-2 lymphomas reveals their common origin

21 January 2018

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A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14

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Substrate binding and sequence preference of the proteasome revealed by active-site-directed affinity probes

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Not such a dismal science: the economics of protein synthesis, folding, degradation and antigen processing

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Vinyl Sulfones as Mechanism-Based Cysteine Protease Inhibitors

21 January 2018

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Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity

21 January 2018

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T cell-mediated tumor rejection displays diverse dependence upon perforin and IFN-gamma mechanisms that cannot be predicted from in vitro T cell characteristics

21 January 2018

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Cathepsin S controls the trafficking and maturation of MHC class II molecules in dendritic cells.

21 January 2018

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Cathepsin S activity regulates antigen presentation and immunity

21 January 2018

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Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T

21 January 2018

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Crystal structure of a deubiquitinating enzyme (human UCH-L3) at 1.8 Å resolution

21 January 2018

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Functional deficiencies of components of the MHC class I antigen pathway in human tumors of epithelial origin

21 January 2018

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The HLA crossroad in tumor immunology

21 January 2018

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Processing of some antigens by the standard proteasome but not by the immunoproteasome results in poor presentation by dendritic cells

21 January 2018

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c-myc overexpression activates alternative pathways for intracellular proteolysis in lymphoma cells.

21 January 2018

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MYC overexpression imposes a nonimmunogenic phenotype on Epstein-Barr virus-infected B cells

21 January 2018

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A proteolytic system that compensates for loss of proteasome function

21 January 2018

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The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M211221200

Short-lived green fluorescent proteins for quantifying ubiquitin/proteasome-dependent proteolysis in living cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M211221200

Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M211221200

Stability of surface H-2K(b), H-2D(b), and peptide-receptive H-2K(b) on splenocytes

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M211221200

21 January 2018

Identifiers

DOI

10.1074/JBC.M211221200

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1 December 2017

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