Micro-dystrophin cDNA ameliorates dystrophic phenotypes when introduced into mdx mice as a transgene (Q44020748)

29 November 2017

title

Micro-dystrophin cDNA ameliorates dystrophic phenotypes when introduced into mdx mice as a transgene (English)

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29 November 2017

Miki Sakamoto

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29 November 2017

Katsutoshi Yuasa

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29 November 2017

Madoka Yoshimura

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29 November 2017

Toshifumi Yokota

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29 November 2017

Takaaki Ikemoto

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29 November 2017

Misao Suzuki

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29 November 2017

George Dickson

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29 November 2017

Yuko Miyagoe-Suzuki

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29 November 2017

Shin'ichi Takeda

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29 November 2017

language of work or name

English

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publication date

1 May 2002

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Biochemical and Biophysical Research Communications

29 November 2017

published in

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29 November 2017

volume

293

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29 November 2017

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29 November 2017

page(s)

1265-1272

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Complete cloning of the duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals

29 November 2017

cites work

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Analysis of the actin-binding domain of alpha-actinin by mutagenesis and demonstration that dystrophin contains a functionally homologous domain

7 January 2021

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A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin.

7 January 2021

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The dystrophin complex forms a mechanically strong link between the sarcolemma and costameric actin

7 January 2021

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Molecular organization at the glycoprotein-complex-binding site of dystrophin. Three dystrophin-associated proteins bind directly to the carboxy-terminal portion of dystrophin

7 January 2021

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Three muscular dystrophies: loss of cytoskeleton-extracellular matrix linkage.

7 January 2021

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Dystrophin protects the sarcolemma from stresses developed during muscle contraction

7 January 2021

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Role of nitric oxide in the pathogenesis of muscular dystrophies: a "two hit" hypothesis of the cause of muscle necrosis

7 January 2021

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Gene therapy for muscular dystrophies: current status and future prospects

7 January 2021

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Very mild muscular dystrophy associated with the deletion of 46% of dystrophin

7 January 2021

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Expression of human full-length and minidystrophin in transgenic mdx mice: implications for gene therapy of Duchenne muscular dystrophy

7 January 2021

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Expression of full-length and truncated dystrophin mini-genes in transgenic mdx mice

7 January 2021

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Effective restoration of dystrophin-associated proteins in vivo by adenovirus-mediated transfer of truncated dystrophin cDNAs

7 January 2021

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Effective adenovirus-mediated gene expression in adult murine skeletal muscle

7 January 2021

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Adeno-associated virus vector carrying human minidystrophin genes effectively ameliorates muscular dystrophy in mdx mouse model

7 January 2021

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Efficient selection for high-expression transfectants with a novel eukaryotic vector

7 January 2021

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Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase

7 January 2021

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Immune response to adenovirus-delivered antigens upregulates utrophin and results in mitigation of muscle pathology in mdx mice

7 January 2021

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alpha1-syntrophin gene disruption results in the absence of neuronal-type nitric-oxide synthase at the sarcolemma but does not induce muscle degeneration

7 January 2021

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Contractile properties of diaphragm muscle segments from old mdx and old transgenic mdx mice

7 January 2021

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Human dystrophin expression in mdx mice after intramuscular injection of DNA constructs

7 January 2021

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Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase.

7 January 2021

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The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy

7 January 2021

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A cluster of basic repeats in the dystrophin rod domain binds F-actin through an electrostatic interaction

7 January 2021

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Dp71 can restore the dystrophin-associated glycoprotein complex in muscle but fails to prevent dystrophy.

7 January 2021

1 reference

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A nitric oxide synthase transgene ameliorates muscular dystrophy in mdx mice

7 January 2021

1 reference

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Selective loss of sarcolemmal nitric oxide synthase in Becker muscular dystrophy

7 January 2021

1 reference

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10.1016/S0006-291X(02)00362-5

7 January 2021

Identifiers

DOI

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29 November 2017

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