Redundant pathways for negative feedback regulation of bile acid production (Q44025689)

29 November 2017

title

Redundant pathways for negative feedback regulation of bile acid production (English)

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29 November 2017

Michael Karin

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29 November 2017

Li Wang

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29 November 2017

Yoon-Kwang Lee

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29 November 2017

Donnie Bundman

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29 November 2017

Yunqing Han

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29 November 2017

Sundararajah Thevananther

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29 November 2017

Chang Soo Kim

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29 November 2017

Steven S Chua

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29 November 2017

Ping Wei

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29 November 2017

Richard A Heyman

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29 November 2017

David D Moore

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29 November 2017

language of work or name

English

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publication date

1 June 2002

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29 November 2017

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inferred from page(s)

published in

Developmental Cell

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29 November 2017

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29 November 2017

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29 November 2017

page(s)

721-731

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High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study

29 November 2017

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A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

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Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway

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The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression

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Dual mechanisms for repression of the monomeric orphan receptor liver receptor homologous protein-1 by the orphan small heterodimer partner

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Activation of the promoter of the orphan receptor SHP by orphan receptors that bind DNA as monomers

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Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

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An orphan nuclear receptor lacking a zinc-finger DNA-binding domain: interaction with several nuclear receptors

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CPF: an orphan nuclear receptor that regulates liver-specific expression of the human cholesterol 7alpha-hydroxylase gene

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A novel nonhepatic hydroxycholesterol 7 alpha-hydroxylase that is markedly stimulated by interleukin-1 beta. Characterization in the immature rat ovary

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Nuclear orphan receptors control cholesterol catabolism.

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Bile acid biosynthesis

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7 January 2021

Identification and characterization of a mouse oxysterol 7alpha-hydroxylase cDNA.

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7 January 2021

Two 7 alpha-hydroxylase enzymes in bile acid biosynthesis

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7 January 2021

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Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

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The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

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Chemical genomics: functional analysis of orphan nuclear receptors in the regulation of bile acid metabolism

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An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

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Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4

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7 January 2021

10.1016/S1534-5807(02)00187-9

Identifiers

DOI

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29 November 2017

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