Caspase-9 holoenzyme is a specific and optimal procaspase-3 processing machine (Q33996526)

30 July 2017

title

Caspase-9 holoenzyme is a specific and optimal procaspase-3 processing machine (English)

1 reference

30 July 2017

Qian Yin

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30 July 2017

Hyun Ho Park

1 reference

30 July 2017

Jee Y Chung

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30 July 2017

Su-Chang Lin

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30 July 2017

Yu-Chih Lo

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30 July 2017

Li S da Graca

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30 July 2017

Xuejun Jiang

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30 July 2017

Hao Wu

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30 July 2017

language of work or name

1 reference

1 April 2006

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30 July 2017

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

259-268

1 reference

Engineering a dimeric caspase-9: a re-evaluation of the induced proximity model for caspase activation

30 July 2017

cites work

1 reference

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Molecular mechanisms of caspase regulation during apoptosis

5 July 2018

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Caspase activation: revisiting the induced proximity model

5 July 2018

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Cell death: critical control points

5 July 2018

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The CD95(APO-1/Fas) DISC and beyond

5 July 2018

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Insights into the regulatory mechanism for caspase-8 activation

5 July 2018

1 reference

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A unified model for apical caspase activation

5 July 2018

1 reference

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5 July 2018

Caspases and apoptosis

1 reference

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Mechanisms of caspase activation and inhibition during apoptosis

5 July 2018

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Structural basis for the activation of human procaspase-7

5 July 2018

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Dimer formation drives the activation of the cell death protease caspase 9

5 July 2018

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Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding

5 July 2018

1 reference

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A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

5 July 2018

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5 July 2018

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The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity

5 July 2018

1 reference

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Caspase-9 and APAF-1 form an active holoenzyme

5 July 2018

1 reference

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Caspase-9 can be activated without proteolytic processing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904439

Pro-caspase-3 is a major physiologic target of caspase-8.

5 July 2018

1 reference

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

5 July 2018

1 reference

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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

5 July 2018

1 reference

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Essential role of CED-4 oligomerization in CED-3 activation and apoptosis

5 July 2018

1 reference

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Interaction of the baculovirus anti-apoptotic protein p35 with caspases. Specificity, kinetics, and characterization of the caspase/p35 complex.

5 July 2018

1 reference

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Autoproteolytic activation of pro-caspases by oligomerization

5 July 2018

1 reference

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Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

5 July 2018

1 reference

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Synthetic activation of caspases: artificial death switches

5 July 2018

1 reference

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An induced proximity model for caspase-8 activation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904439

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904439

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904439

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904439

Sequence requirements for coiled-coils: analysis with lambda repressor-GCN4 leucine zipper fusions

5 July 2018

1 reference

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Improved methods for building protein models in electron density maps and the location of errors in these models

5 July 2018

1 reference

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X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil

5 July 2018

1 reference

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Regulation of the Apaf-1/caspase-9 apoptosome by caspase-3 and XIAP.

5 July 2018

1 reference

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Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.

29 October 2018

1 reference

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Dimeric procaspase-3 unfolds via a four-state equilibrium process

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904439

Removal of the pro-domain does not affect the conformation of the procaspase-3 dimer.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904439

A structure of the human apoptosome at 12.8 A resolution provides insights into this cell death platform

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16630893

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16630893

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Quantification of active caspase 3 in apoptotic cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16630893

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLCEL.2006.03.030

1 reference

30 July 2017

1 reference

30 July 2017

1 reference