Met-related receptor tyrosine kinase Ron in tumor growth and metastasis. (Q33916081)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18620091%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

review article

1 reference

title

Met-related receptor tyrosine kinase Ron in tumor growth and metastasis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18620091%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18620091%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Purnima K Wagh

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18620091%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Belinda E Peace

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18620091%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

publication date

1 January 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18620091%20AND%20SRC:MED&resulttype=core&format=json

Advances in Cancer Research

10 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18620091%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

volume

100

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18620091%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

page(s)

1-33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18620091%20AND%20SRC:MED&resulttype=core&format=json

Angiogenesis inhibitors. Drug selectivity and target specificity.

10 January 2020

cites work

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The RON receptor tyrosine kinase mediates oncogenic phenotypes in pancreatic cancer cells and is increasingly expressed during pancreatic cancer progression.

5 July 2018

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Coordinate expression and functional profiling identify an extracellular proteolytic signaling pathway

5 July 2018

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5 July 2018

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Collaboration of RON and epidermal growth factor receptor in human bladder carcinogenesis.

5 July 2018

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5 July 2018

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Therapeutic implications of a human neutralizing antibody to the macrophage-stimulating protein receptor tyrosine kinase (RON), a c-MET family member

5 July 2018

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Geldanamycins trigger a novel Ron degradative pathway, hampering oncogenic signaling.

5 July 2018

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5 July 2018

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Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene

5 July 2018

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Repression of the MSP/MST-1 gene contributes to the antiapoptotic gain of function of mutant p53

5 July 2018

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Altered exon usage in the juxtamembrane domain of mouse and human RON regulates receptor activity and signaling specificity

5 July 2018

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Gefitinib (ZD1839, Iressa) in non-small-cell lung cancer: a review of clinical trials from a daily practice perspective.

5 July 2018

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Co-expression of RON and MET is a prognostic indicator for patients with transitional-cell carcinoma of the bladder

5 July 2018

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Monoclonal antibodies targeting epidermal growth factor receptor and vascular endothelial growth factor with a focus on head and neck tumors

5 July 2018

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Prognostic significance of co-expression of RON and MET receptors in node-negative breast cancer patients.

5 July 2018

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Interplay between scatter factor receptors and B plexins controls invasive growth

5 July 2018

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Antitumor activity of HKI-272, an orally active, irreversible inhibitor of the HER-2 tyrosine kinase

5 July 2018

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Collaborative activities of macrophage-stimulating protein and transforming growth factor-beta1 in induction of epithelial to mesenchymal transition: roles of the RON receptor tyrosine kinase

5 July 2018

1 reference

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Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors

5 July 2018

1 reference

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The soluble sema domain of the RON receptor inhibits macrophage-stimulating protein-induced receptor activation

5 July 2018

1 reference

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Cross-talk between the receptor tyrosine kinases Ron and epidermal growth factor receptor

5 July 2018

1 reference

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Cis-acting elements in the hepatocyte growth factor-like protein gene regulate kidney and liver-specific expression in mice

5 July 2018

1 reference

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The MSP receptor regulates alpha6beta4 and alpha3beta1 integrins via 14-3-3 proteins in keratinocyte migration

5 July 2018

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5 July 2018

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7 January 2021

The RON and MET oncogenes are co-expressed in human ovarian carcinomas and cooperate in activating invasiveness

1 reference

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The Ron proto-oncogene product is a phenotypic marker of renal oncocytoma

5 July 2018

1 reference

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Quantitation of membrane type serine protease 1 (MT-SP1) in transformed and normal cells

5 July 2018

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Tissue microarray analysis of hepatocyte growth factor/Met pathway components reveals a role for Met, matriptase, and hepatocyte growth factor activator inhibitor 1 in the progression of node-negative breast cancer

5 July 2018

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Receptor tyrosine kinase Ron is expressed in mouse reproductive tissues during embryo implantation and is important in trophoblast cell function

5 July 2018

1 reference

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Oncogenic signaling pathways activated by RON receptor tyrosine kinase

5 July 2018

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Altered expression of the RON receptor tyrosine kinase in primary human colorectal adenocarcinomas: generation of different splicing RON variants and their oncogenic potential

5 July 2018

1 reference

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The protein kinase complement of the human genome

5 July 2018

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Multiple pulmonary adenomas in the lung of transgenic mice overexpressing the RON receptor tyrosine kinase. Recepteur d'origine nantais

5 July 2018

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Feline STK gene expression in mammary carcinomas

5 July 2018

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Macrophage-stimulating protein is produced by tubular cells and activates mesangial cells

5 July 2018

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Macrophage stimulating protein (MSP) evokes superoxide anion production by human macrophages of different origin

5 July 2018

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Point mutations and overexpression of Ron induce transformation, tumor formation, and metastasis

5 July 2018

1 reference

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Ron-mediated cytoplasmic signaling is dispensable for viability but is required to limit inflammatory responses

5 July 2018

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Oncogenic mutants of RON and MET receptor tyrosine kinases cause activation of the beta-catenin pathway

5 July 2018

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The envelope glycoprotein of friend spleen focus-forming virus covalently interacts with and constitutively activates a truncated form of the receptor tyrosine kinase Stk.

5 July 2018

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alpha 1-Antichymotrypsin is the human plasma inhibitor of macrophage ectoenzymes that cleave pro-macrophage stimulating protein

5 July 2018

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Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression

5 July 2018

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The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor tyrosine kinase

5 July 2018

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Identification of a novel splicing product of the RON receptor tyrosine kinase in human colorectal carcinoma cells

5 July 2018

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Cross-talk between the proto-oncogenes Met and Ron

5 July 2018

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Integrin-mediated RON growth factor receptor phosphorylation requires tyrosine kinase activity of both the receptor and c-Src

5 July 2018

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Protein kinase expression during murine mammary development

5 July 2018

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Two independent signaling pathways mediate the antiapoptotic action of macrophage-stimulating protein on epithelial cells

5 July 2018

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MET(PRC) mutations in the Ron receptor result in upregulation of tyrosine kinase activity and acquisition of oncogenic potential

5 July 2018

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5 July 2018

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Fv2 encodes a truncated form of the Stk receptor tyrosine kinase

5 July 2018

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Presence of RON receptor tyrosine kinase and its splicing variant in malignant and non-malignant human colonic mucosa

5 July 2018

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Chicken macrophage stimulating protein is a ligand of the receptor protein-tyrosine kinase Sea.

5 July 2018

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The Ron/STK receptor tyrosine kinase is essential for peri-implantation development in the mouse

5 July 2018

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Macrophage stimulating protein-induced epithelial cell adhesion is mediated by a PI3-K-dependent, but FAK-independent mechanism

5 July 2018

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Characterization of two monoclonal antibodies against the RON tyrosine kinase receptor

5 July 2018

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Point mutations in the tyrosine kinase domain release the oncogenic and metastatic potential of the Ron receptor

5 July 2018

1 reference

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Overexpression of the RON gene in human breast carcinoma

5 July 2018

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Macrophage-stimulating protein and its receptor in non-small-cell lung tumors: induction of receptor tyrosine phosphorylation and cell migration

5 July 2018

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Biological effects of targeted inactivation of hepatocyte growth factor-like protein in mice

5 July 2018

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Characterization of the mouse Ron/Stk receptor tyrosine kinase gene

5 July 2018

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Functional Characterization of Domains Contained in Hepatocyte Growth Factor-like Protein

5 July 2018

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Differential screening of a human chromosome 3 library identifies hepatocyte growth factor-like/macrophage-stimulating protein and its receptor in injured lung. Possible implications for neuroendocrine cell survival

5 July 2018

1 reference

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Role of macrophage-stimulating protein and its receptor, RON tyrosine kinase, in ciliary motility

5 July 2018

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Constitutive activation of the RON gene promotes invasive growth but not transformation

5 July 2018

1 reference

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STK/RON receptor tyrosine kinase mediates both apoptotic and growth signals via the multifunctional docking site conserved among the HGF receptor family

5 July 2018

1 reference

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A splicing variant of the RON transcript induces constitutive tyrosine kinase activity and an invasive phenotype

5 July 2018

1 reference

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The tyrosine kinase receptors Ron and Sea control "scattering" and morphogenesis of liver progenitor cells in vitro

5 July 2018

1 reference

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Macrophage-stimulating protein induces proliferation and migration of murine keratinocytes.

5 July 2018

1 reference

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Hepatocyte nuclear factor-4 is responsible for the liver-specific expression of the gene coding for hepatocyte growth factor-like protein

5 July 2018

1 reference

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Proteolytic cleavage and activation of pro-macrophage-stimulating protein by resident peritoneal macrophage membrane proteases

5 July 2018

1 reference

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Expression and maturation of the cellular sea receptor, a member of the hepatocyte growth factor (HGF) receptor family of protein tyrosine kinases.

5 July 2018

1 reference

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The proto-oncogene RON is involved in development of epithelial, bone and neuro-endocrine tissues.

5 July 2018

1 reference

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Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins and locates the MSP gene on chromosome 3

5 July 2018

1 reference

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The protooncogene c-sea encodes a transmembrane protein-tyrosine kinase related to the Met/hepatocyte growth factor/scatter factor receptor

5 July 2018

1 reference

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A novel putative receptor protein tyrosine kinase of the met family

5 July 2018

1 reference

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Hepatocyte growth factor-like protein is identical to macrophage stimulating protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Molecular cloning of a novel receptor tyrosine kinase gene, STK, derived from enriched hematopoietic stem cells.

5 July 2018

1 reference

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RON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP

5 July 2018

1 reference

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Identification of the ron gene product as the receptor for the human macrophage stimulating protein

5 July 2018

1 reference

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Proteolytic conversion of single chain precursor macrophage-stimulating protein to a biologically active heterodimer by contact enzymes of the coagulation cascade

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Macrophage-stimulating protein activates Ras by both activation and translocation of SOS nucleotide exchange factor

5 July 2018

1 reference

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Macrophage stimulating protein: purification, partial amino acid sequence, and cellular activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Characterization of the DNF15S2 locus on human chromosome 3: identification of a gene coding for four kringle domains with homology to hepatocyte growth factor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Cultured Müller cells have high levels of epidermal growth factor receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Mammary-specific Ron receptor overexpression induces highly metastatic mammary tumors associated with beta-catenin activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Ron receptor signaling augments mammary tumor formation and metastasis in a murine model of breast cancer

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Ron tyrosine kinase receptor regulates papilloma growth and malignant conversion in a murine model of skin carcinogenesis.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Nitric oxide, a mediator of inflammation, suppresses tumorigenesis.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

RNA-mediated gene silencing of the RON receptor tyrosine kinase alters oncogenic phenotypes of human colorectal carcinoma cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Dual-agent molecular targeting of the epidermal growth factor receptor (EGFR): combining anti-EGFR antibody with tyrosine kinase inhibitor.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Truncated RON tyrosine kinase drives tumor cell progression and abrogates cell-cell adhesion through E-cadherin transcriptional repression

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Discovery of frequent homozygous deletions in chromosome 3p21.3 LUCA and AP20 regions in renal, lung and breast carcinomas

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

United States Food and Drug Administration Drug Approval summary: Gefitinib (ZD1839; Iressa) tablets

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

The receptor tyrosine kinase Ron is expressed in the mouse ovary and regulates inducible nitric oxide synthase levels and ovulation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Combined antiestrogen, antiangiogenic and anti-invasion therapy inhibits primary and metastatic tumor growth in the MMTVneu model of breast cancer.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Activation of CR3-mediated phagocytosis by MSP requires the RON receptor, tyrosine kinase activity, phosphatidylinositol 3-kinase, and protein kinase C zeta

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Deletion mapping using quantitative real-time PCR identifies two distinct 3p21.3 regions affected in most cervical carcinomas

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Deletion of the Ron receptor tyrosine kinase domain in mice provides protection from endotoxin-induced acute liver failure.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Sequential histopathological changes in vivo after suicide gene therapy of gastric cancer induced by N-methyl-N'-nitro-N-nitrosoguanidine in rats

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Three receptor genes for plasminogen related growth factors in the genome of the puffer fish Fugu rubripes

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Deregulated inflammatory response in mice lacking the STK/RON receptor tyrosine kinase

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Restricted expression of the ron gene encoding the macrophage stimulating protein receptor during mouse development.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Characterization of the mouse cDNA and gene coding for a hepatocyte growth factor-like protein: expression during development

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102433

Multiple pulmonary adenomas in the lung of transgenic mice overexpressing the RON receptor tyrosine kinase

29 October 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2900001-8

7 January 2021

Prognostic Value of Serum Proteins Synthesized by Breast Carcinoma Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2900001-8

7 January 2021

RTK and TGF-β signaling pathways genes in the sea urchin genome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2900001-8

7 January 2021

Estradiol increases the production of alpha 1-antichymotrypsin in MCF7 and T47D human breast cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2900001-8

7 January 2021

Induction of cell shape changes through activation of the interleukin-3 common beta chain receptor by the RON receptor-type tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2900001-8

7 January 2021

Action and target cell specificity of human macrophage-stimulating protein (MSP)

1 reference

12 December 2020

Macrophage-stimulating protein inhibits induction of nitric oxide production by endotoxin- or cytokine-stimulated mouse macrophages

1 reference

12 December 2020

Requirement of phosphatidylinositol-3 kinase for epithelial cell migration activated by human macrophage stimulating protein

1 reference

12 December 2020

Co-expression and regulation of Met and Ron proto-oncogenes in human hepatocellular carcinoma tissues and cell lines

1 reference

12 December 2020

Activation of the RON receptor tyrosine kinase inhibits inducible nitric oxide synthase (iNOS) expression by murine peritoneal exudate macrophages: phosphatidylinositol-3 kinase is required for RON-mediated inhibition of iNOS expression

1 reference

12 December 2020

10.1016/S0065-230X(08)00001-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18620091%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18620091%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

PubMed publication ID

18620091

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18620091%20AND%20SRC:MED&resulttype=core&format=json