Adamantyl-substituted retinoid-derived molecules that interact with the orphan nuclear receptor small heterodimer partner: effects of replacing the 1-adamantyl or hydroxyl group on inhibition of cancer cell growth, induction of cancer cell apoptosis (Q33900787)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	Adamantyl-substituted retinoid-derived molecules that interact with the orphan nuclear receptor small heterodimer partner: effects of replacing the 1-adamantyl or hydroxyl group on inhibition of cancer cell growth, induction of cancer cell apoptosis	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Adamantyl-substituted retinoid-derived molecules that interact with the orphan nuclear receptor small heterodimer partner: effects of replacing the 1-adamantyl or hydroxyl group on inhibition of cancer cell growth, induction of cancer cell apoptosis (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

1 reference

based on heuristic

inferred from title

author name string

Marcia I Dawson

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Zebin Xia

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Tao Jiang

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Mao Ye

4

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Joseph A Fontana

5

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Lulu Farhana

6

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Bhaumik Patel

7

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Li Ping Xue

8

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Mohammad Bhuiyan

9

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Roberto Pellicciari

10

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Antonio Macchiarulo

11

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Roberto Nuti

12

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Xiao-Kun Zhang

13

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Young-Hoon Han

14

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Lutz Tautz

15

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Peter D Hobbs

16

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Ling Jong

17

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Nahid Waleh

18

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Wan-Ru Chao

19

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Gen-Sheng Feng

20

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Yuhong Pang

21

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Ying Su

22

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

language of work or name

0 references

publication date

30 August 2008

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Journal of Medicinal Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

51

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

18

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

5650-5662

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Structure and function of the atypical orphan nuclear receptor small heterodimer partner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Synthesis and structure-activity relationships of new antiproliferative and proapoptotic retinoid-related biphenyl-4-yl-acrylic acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

SHP-2 tyrosine phosphatase inhibits p73-dependent apoptosis and expression of a subset of p53 target genes induced by EGCG.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Adamantyl-substituted retinoid-related molecules bind small heterodimer partner and modulate the Sin3A repressor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

International Union of Pharmacology. LXVI. Orphan nuclear receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Dosage-sensitive sex reversal adrenal hypoplasia congenita critical region on the X chromosome, gene 1 (DAX1) (NR0B1) and small heterodimer partner (SHP) (NR0B2) form homodimers individually, as well as DAX1-SHP heterodimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Global detection of molecular changes reveals concurrent alteration of several biological pathways in nonsmall cell lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Synthesis and structure-activity relationships of a new series of retinoid-related biphenyl-4-ylacrylic acids endowed with antiproliferative and proapoptotic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Apoptosis induction by a novel retinoid-related molecule requires nuclear factor-kappaB activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

SHP represses transcriptional activity via recruitment of histone deacetylases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Cellular and pharmacological bases of the antitumor activity of a novel adamantyl retinoid, ST1926.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Antagonist analogue of 6-[3'-(1-adamantyl)-4'-hydroxyphenyl]-2-naphthalenecarboxylic acid (AHPN) family of apoptosis inducers that effectively blocks AHPN-induced apoptosis but not cell-cycle arrest

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Apoptosis signaling by the novel compound 3-Cl-AHPC involves increased EGFR proteolysis and accompanying decreased phosphatidylinositol 3-kinase and AKT kinase activities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Identification and characterization of a cell cycle and apoptosis regulatory protein-1 as a novel mediator of apoptosis signaling by retinoid CD437

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Gab1, SHP-2 and other novel regulators of Ras: targets for anticancer drug discovery?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Comparison of various types of hydrogen bonds involving aromatic amino acids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Induction of apoptosis of human B-CLL and ALL cells by a novel retinoid and its nonretinoidal analog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Molecular recognition of agonist ligands by RXRs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

A transcriptional inhibitor targeted by the atypical orphan nuclear receptor SHP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Retinoid-related molecules induce cytochrome c release and apoptosis through activation of c-Jun NH(2)-terminal kinase/p38 mitogen-activated protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

The structure of the ultraspiracle ligand-binding domain reveals a nuclear receptor locked in an inactive conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Crystal structure of the ligand-binding domain of the ultraspiracle protein USP, the ortholog of retinoid X receptors in insects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Identification of a unique binding protein specific for a novel retinoid inducing cellular apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

Synthesis, structure-affinity relationships, and biological activities of ligands binding to retinoic acid receptor subtypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

p53 independent G0/G1 arrest and apoptosis induced by a novel retinoid in human breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

5 July 2018

An adamantyl-substituted retinoid-derived molecule that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nuclear receptor: effects of modifying its carboxylate group on apoptosis, proliferatio

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

29 October 2018

SHP-2 positively regulates adipogenic differentiation in 3T3-L1 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

29 October 2018

The retinoid-X receptor ortholog, ultraspiracle, binds with nanomolar affinity to an endogenous morphogenetic ligand.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

29 October 2018

Unveiling hidden features of orphan nuclear receptors: the case of the small heterodimer partner (SHP).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

29 October 2018

Differential role of the loop region between helices H6 and H7 within the orphan nuclear receptors small heterodimer partner and DAX-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

29 October 2018

Induction of apoptosis in retinoid-refractory acute myelogenous leukemia by a novel AHPN analog.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

29 October 2018

A novel atypical retinoid endowed with proapoptotic and antitumor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

29 October 2018

Differential response of human acute myeloid leukemia cells to gemtuzumab ozogamicin in vitro: role of Chk1 and Chk2 phosphorylation and caspase 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

29 October 2018

Molecular effects of topoisomerase II inhibitors in AML cell lines: correlation of apoptosis with topoisomerase II activity but not with DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

29 October 2018

Noonan syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097887

10 December 2018

A canonical structure for the ligand-binding domain of nuclear receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18759424

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A selective retinoid with high activity against an androgen-resistant prostate cancer cell type

1 reference

https://pubmed.ncbi.nlm.nih.gov/18759424

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Overexpression of Shp-2 is associated with the unlimited growth and apoptosis resistance of p210 bcr-abl-mediated chronic myeloid leukemia]

1 reference

https://pubmed.ncbi.nlm.nih.gov/18759424

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor Activity of the Retinoid-Related Molecules (E)-3-(4'-Hydroxy-3'-adamantylbiphenyl-4-yl)acrylic Acid (ST1926) and 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene Carboxylic Acid (CD437) in F9 Teratocarcinoma: Role of Retinoic Acid Receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18759424

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and functional effects of disease-causing amino acid substitutions affecting residues Ala72 and Glu76 of the protein tyrosine phosphatase SHP-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/18759424

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JM800456K

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q33900787&oldid=2165370841"