Curcumin reduces expression of Bcl-2, leading to apoptosis in daunorubicin-insensitive CD34+ acute myeloid leukemia cell lines and primary sorted CD34+ acute myeloid leukemia cells (Q33906004)

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scientific article published on May 19, 2011

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English	Curcumin reduces expression of Bcl-2, leading to apoptosis in daunorubicin-insensitive CD34+ acute myeloid leukemia cell lines and primary sorted CD34+ acute myeloid leukemia cells	scientific article published on May 19, 2011

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

Curcumin reduces expression of Bcl-2, leading to apoptosis in daunorubicin-insensitive CD34+ acute myeloid leukemia cell lines and primary sorted CD34+ acute myeloid leukemia cells (English)

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Europe PubMed Central

PubMed publication ID

29 July 2017

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acute myeloid leukemia

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3

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Fei-Meng Zheng

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21595920

2 December 2024

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Jia Rao

1

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Europe PubMed Central

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29 July 2017

Duo-Rong Xu

2

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29 July 2017

Zi-Jie Long

4

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29 July 2017

Sheng-Shan Huang

5

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Europe PubMed Central

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29 July 2017

Xing Wu

6

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29 July 2017

Wei-Hua Zhou

7

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29 July 2017

Ren-Wei Huang

8

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29 July 2017

Quentin Liu

9

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Europe PubMed Central

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29 July 2017

language of work or name

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National Center for Biotechnology Information

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21595920

2 December 2024

publication date

19 May 2011

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Europe PubMed Central

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29 July 2017

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https://translational-medicine.biomedcentral.com/counter/pdf/10.1186/1479-5876-9-71

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21595920

2 December 2024

https://europepmc.org/articles/PMC3118333

online access status

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Europe PubMed Central

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21595920

2 December 2024

https://europepmc.org/articles/PMC3118333?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21595920

2 December 2024

https://link.springer.com/content/pdf/10.1186/1479-5876-9-71.pdf

Portable Document Format

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10.1186/1479-5876-9-71

https://api.crossref.org/works/10.1186/1479-5876-9-71

2 December 2024

Journal of Translational Medicine

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Europe PubMed Central

PubMed publication ID

29 July 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

71

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Curcumin Enhances the Effect of Cisplatin in Suppression of Head and Neck Squamous Cell Carcinoma via Inhibition of IKKβ Protein of the NFκB Pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Distinct combinatorial effects of the plant polyphenols curcumin, carnosic acid, and silibinin on proliferation and apoptosis in acute myeloid leukemia cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Drug combination studies and their synergy quantification using the Chou-Talalay method

1 reference

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5 July 2018

Elimination of Colon Cancer Stem-Like Cells by the Combination of Curcumin and FOLFOX.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Oral administration of heat-solubilized curcumin for potentially increasing curcumin bioavailability in experimental animals

1 reference

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5 July 2018

Potent growth suppressive activity of curcumin in human breast cancer cells: Modulation of Wnt/beta-catenin signaling.

1 reference

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5 July 2018

Curcumin in combination with bortezomib synergistically induced apoptosis in human multiple myeloma U266 cells

1 reference

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5 July 2018

Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets

1 reference

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5 July 2018

Curcumin inhibits Akt/mammalian target of rapamycin signaling through protein phosphatase-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

c-Jun N-terminal kinase activation failure is a new mechanism of anthracycline resistance in acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Phase II trial of curcumin in patients with advanced pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Curcumin and cancer: an "old-age" disease with an "age-old" solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Curcumin down-regulates the multidrug-resistance mdr1b gene by inhibiting the PI3K/Akt/NF kappa B pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Improving the solubility and pharmacological efficacy of curcumin by heat treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Inhibition of pancreatic and lung adenocarcinoma cell survival by curcumin is associated with increased apoptosis, down-regulation of COX-2 and EGFR and inhibition of Erk1/2 activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Acute myeloid leukaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Curcumin-induced apoptosis in human leukemia cell HL-60 is associated with inhibition of telomerase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Dose escalation of a curcuminoid formulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Gene profiling study of G3139- and Bcl-2-targeting siRNAs identifies a unique G3139 molecular signature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Drug therapy for acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Tumour stem cells and drug resistance

1 reference

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5 July 2018

Role of mitochondrial membrane permeabilization in apoptosis and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

An undifferentiated variant derived from the human acute myelogenous leukemia cell line (KG-1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Establishment of a human acute myeloid leukemia cell line (Kasumi-1) with 8;21 chromosome translocation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

5 July 2018

Prognostic relevance of immunophenotyping in 379 patients with acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1186%2F1479-5876-9-71

21 January 2018

Ruthenium red, inhibitor of mitochondrial Ca2+ uniporter, inhibits curcumin-induced apoptosis via the prevention of intracellular Ca2+ depletion and cytochrome c release

1 reference

https://api.crossref.org/works/10.1186%2F1479-5876-9-71

21 January 2018

Curcumin induces apoptosis via inhibition of PI3'-kinase/AKT pathway in acute T cell leukemias

1 reference

https://api.crossref.org/works/10.1186%2F1479-5876-9-71

21 January 2018

Curcumin (diferuloylmethane) inhibits constitutive active NF-kappaB, leading to suppression of cell growth of human T-cell leukemia virus type I-infected T-cell lines and primary adult T-cell leukemia cells

1 reference

https://api.crossref.org/works/10.1186%2F1479-5876-9-71

21 January 2018

Notch-1 down-regulation by curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118333

29 October 2018

Consumption of the putative chemopreventive agent curcumin by cancer patients: assessment of curcumin levels in the colorectum and their pharmacodynamic consequences

1 reference

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29 October 2018

Differences in anti-apoptotic and multidrug resistance phenotypes in elderly and young acute myeloid leukemia patients are related to the maturation of blast cells.

1 reference

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29 October 2018

Bcl-2 overexpression prevents daunorubicin-induced apoptosis through inhibition of XIAP and Akt degradation

1 reference

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29 October 2018

Differences between the CD34+ and CD34- blast compartments in apoptosis resistance in acute myeloid leukemia

1 reference

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Immunophenotyping is an independent factor for risk stratification in AML.

1 reference

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29 October 2018

The anti-apoptotic genes Bcl-X(L) and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells

1 reference

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Plasma pharmacokinetics of adriamycin and adriamycinol: implications for the design of in vitro experiments and treatment protocols.

1 reference

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29 October 2018

High frequency of immunophenotype changes in acute myeloid leukemia at relapse: implications for residual disease detection (Cancer and Leukemia Group B Study 8361)

1 reference

https://api.crossref.org/works/10.1186%2F1479-5876-9-71

21 January 2018

CD34+ leukemic subpopulation predominantly displays lower spontaneous apoptosis and has higher expression levels of Bcl-2 and MDR1 genes than CD34- cells in childhood AML

1 reference

https://pubmed.ncbi.nlm.nih.gov/21595920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural resistance of acute myeloid leukemia cell lines to mitoxantrone is associated with lack of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21595920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic importance of immunophenotyping in adults with acute myelocytic leukaemia: the significance of the stem-cell glycoprotein CD34 (My10)

1 reference

https://pubmed.ncbi.nlm.nih.gov/21595920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of correlation between expression and function of P-glycoprotein in acute myeloid leukemia cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/21595920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Prognostic Significance of the CD34 Antigen in Acute Myeloid Leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21595920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Addition in drug combination (author's transl)

1 reference

https://pubmed.ncbi.nlm.nih.gov/21595920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

10

88

497

author name string

A van-Stijn

publication date

2003

1 reference

10.1186/1479-5876-9-71

https://api.crossref.org/works/10.1186/1479-5876-9-71

2 December 2024

11

90

54

author name string

L Suarez

publication date

2005

1 reference

10.1186/1479-5876-9-71

https://api.crossref.org/works/10.1186/1479-5876-9-71

2 December 2024

Acta Pharmacologica Sinica

36

1

70

author name string

ZJ Jin

publication date

1980

1 reference

10.1186/1479-5876-9-71

https://api.crossref.org/works/10.1186/1479-5876-9-71

2 December 2024

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10.1186/1479-5876-9-71

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Dimensions Publication ID

1 reference

https://scigraph.springernature.com/pub.10.1186/1479-5876-9-71

9 September 2019

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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