The inflammatory network: bridging senescent stroma and epithelial tumorigenesis (Q33807763)

29 July 2017

1 reference

title

The inflammatory network: bridging senescent stroma and epithelial tumorigenesis (English)

1 reference

29 July 2017

Weiwei Shan

1 reference

29 July 2017

Gong Yang

series ordinal

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29 July 2017

Jinsong Liu

series ordinal

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29 July 2017

publication date

1 January 2009

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29 July 2017

published in

Frontiers in Bioscience

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29 July 2017

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29 July 2017

page(s)

4044-4057

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Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

29 July 2017

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The guardian's little helper: microRNAs in the p53 tumor suppressor network

4 July 2018

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microRNAs join the p53 network--another piece in the tumour-suppression puzzle

4 July 2018

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4 July 2018

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4 July 2018

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Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis.

4 July 2018

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ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence

4 July 2018

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Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion

4 July 2018

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

4 July 2018

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Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

4 July 2018

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The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis

4 July 2018

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Stromal-epithelial interaction in prostate cancer progression

4 July 2018

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Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing

4 July 2018

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p16INK4a induces an age-dependent decline in islet regenerative potential

4 July 2018

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A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation

4 July 2018

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Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence

4 July 2018

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Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer.

4 July 2018

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High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras

4 July 2018

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Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

4 July 2018

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BRAFE600-associated senescence-like cell cycle arrest of human naevi

4 July 2018

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Li-Fraumeni syndrome: a p53 family affair

4 July 2018

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Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

4 July 2018

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Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

4 July 2018

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Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation

4 July 2018

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Context, tissue plasticity, and cancer: are tumor stem cells also regulated by the microenvironment?

4 July 2018

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Friends or foes - bipolar effects of the tumour stroma in cancer

4 July 2018

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DNA damage checkpoint kinase Chk2 triggers replicative senescence

4 July 2018

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Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

4 July 2018

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Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock

4 July 2018

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When cells get stressed: an integrative view of cellular senescence

4 July 2018

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Tissue architecture: the ultimate regulator of breast epithelial function

4 July 2018

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Soluble factors involved in glioma invasion

4 July 2018

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A DNA damage checkpoint response in telomere-initiated senescence

4 July 2018

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The serial cultivation of human diploid cell strains

4 July 2018

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Involvement of the INK4a/Arf gene locus in senescence

4 July 2018

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Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

4 July 2018

1 reference

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Regulation of wound healing by growth factors and cytokines

4 July 2018

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Cancer and aging: a model for the cancer promoting effects of the aging stroma

4 July 2018

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Historical claims and current interpretations of replicative aging

4 July 2018

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Mouse models for multistep tumorigenesis

4 July 2018

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Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging

4 July 2018

1 reference

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Proteases in invasion: matrix metalloproteinases

4 July 2018

1 reference

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Stromal cells can contribute oncogenic signals

4 July 2018

1 reference

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Overexpression of interleukin-6 in human basal cell carcinoma cell lines increases anti-apoptotic activity and tumorigenic potency.

4 July 2018

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Tubular cell senescence and expression of TGF-beta1 and p21(WAF1/CIP1) in tubulointerstitial fibrosis of aging rats

4 July 2018

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Cancer and age in the USA.

4 July 2018

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Know thy neighbor: stromal cells can contribute oncogenic signals

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858971

4 July 2018

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4 July 2018

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The influence of the microenvironment on the malignant phenotype

4 July 2018

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Recent advances in research on multistage tumorigenesis

4 July 2018

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Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells

4 July 2018

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Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor

4 July 2018

1 reference

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Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium

4 July 2018

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Senescence-associated beta-galactosidase histochemistry for the primate eye.

4 July 2018

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Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

4 July 2018

1 reference

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Aging and cancer: the role of stromal interactions with epithelial cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858971

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

4 July 2018

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Suppression of human bladder cancer growth by increased expression of C-CAM1 gene in an orthotopic model.

4 July 2018

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Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent

4 July 2018

1 reference

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Age-dependent regulation of the tumorigenic potential of neoplastically transformed rat liver epithelial cells by the liver microenvironment

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858971

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

4 July 2018

1 reference

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Cancer: the rise of the genetic paradigm

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858971

Stromal-epithelial interactions in adult organs

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858971

A statistical model to estimate variance in long term-low dose mutation assays: testing of the model in a human lymphoblastoid mutation assay.

4 July 2018

1 reference

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Mesenchyme-induced changes in the neoplastic characteristics of the Dunning prostatic adenocarcinoma.

4 July 2018

1 reference

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Stromal regulation of epithelial function

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858971

Expression of interleukin 1-inducible genes and production of interleukin 1 by aging human fibroblasts

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858971

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

4 July 2018

1 reference

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Reversion of Malignancy and Normalized Differentiation of Teratocarcinoma Cells in Chimeric Mice

4 July 2018

1 reference

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Evidence that senescent human prostate epithelial cells enhance tumorigenicity: cell fusion as a potential mechanism and inhibition by p16INK4a and hTERT.

4 July 2018

1 reference

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Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis.

30 October 2018

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A negative feedback signaling network underlies oncogene-induced senescence

30 October 2018

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The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858971

Oncogene-induced senescence as an initial barrier in lymphoma development

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858971

The stroma as a crucial target in rat mammary gland carcinogenesis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858971

Microarray analysis of replicative senescence

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858971

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858971

Replicative senescence in normal liver, chronic hepatitis C, and hepatocellular carcinomas

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858971

The mutation rate and cancer

30 October 2018

1 reference

12 December 2020

Cellular proliferation potential during aging and caloric restriction in rhesus monkeys (Macaca mulatta)

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12 December 2020

Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis

1 reference

12 December 2020

Destabilization of CHK2 by a missense mutation associated with Li-Fraumeni Syndrome

1 reference

12 December 2020

Androgenic induction of DNA synthesis in prostatic glands induced in the urothelium of testicular feminized (Tfm/Y) mice

1 reference

12 December 2020

Growth of epithelium from a preneoplastic mammary outgrowth in response to mammary adipose tissue

1 reference

12 December 2020

Identifiers

DOI

10.2741/3511

1 reference

29 July 2017

1 reference

29 July 2017

1 reference