Aiolos promotes anchorage independence by silencing p66Shc transcription in cancer cells (Q33806421)

29 July 2017

title

Aiolos promotes anchorage independence by silencing p66Shc transcription in cancer cells (English)

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29 July 2017

Xichuan Li

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29 July 2017

Zhao Xu

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29 July 2017

Wei Du

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29 July 2017

Zhenfa Zhang

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29 July 2017

Yiliang Wei

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29 July 2017

Hao Wang

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29 July 2017

Zhiyan Zhu

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29 July 2017

Litao Qin

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29 July 2017

Lin Wang

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29 July 2017

Qing Niu

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29 July 2017

Xiulan Zhao

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29 July 2017

Luc Girard

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29 July 2017

Yimei Gong

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29 July 2017

Zhenyi Ma

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29 July 2017

Baocun Sun

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29 July 2017

Zhi Yao

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29 July 2017

John D Minna

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29 July 2017

Lance S Terada

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29 July 2017

Zhe Liu

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29 July 2017

publication date

1 May 2014

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29 July 2017

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

575-589

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Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host

29 July 2017

cites work

1 reference

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Mechanisms that link the oncogenic epithelial-mesenchymal transition to suppression of anoikis

4 July 2018

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The genomic landscape of hypodiploid acute lymphoblastic leukemia

4 July 2018

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Aiolos promotes TH17 differentiation by directly silencing Il2 expression

4 July 2018

1 reference

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Upregulation of CXCR4 is functionally crucial for maintenance of stemness in drug-resistant non-small cell lung cancer cells

4 July 2018

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Tumor metastasis: molecular insights and evolving paradigms

4 July 2018

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A pathway for the control of anoikis sensitivity by E-cadherin and epithelial-to-mesenchymal transition

4 July 2018

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Identification of fusion genes in breast cancer by paired-end RNA-sequencing

4 July 2018

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A unique chromatin signature uncovers early developmental enhancers in humans

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

p66Shc restrains Ras hyperactivation and suppresses metastatic behavior

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

p66shc inhibits insulin-like growth factor-I signaling via direct binding to Src through its polyproline and Src homology 2 domains, resulting in impairment of Src kinase activation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Tumor suppressor function of Syk in human MCF10A in vitro and normal mouse mammary epithelium in vivo

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Ras orchestrates exit from the cell cycle and light-chain recombination during early B cell development

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Differential aiolos expression in human hematopoietic subpopulations.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Current status of clinical trials for small cell lung cancer

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Interferon regulatory factors 4 and 8 induce the expression of Ikaros and Aiolos to down-regulate pre-B-cell receptor and promote cell-cycle withdrawal in pre-B-cell development

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

p66Shc mediates anoikis through RhoA

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Combinatorial effects of splice variants modulate function of Aiolos

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Metastasis: a question of life or death

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Sustained activation of cell adhesion is a differentially regulated process in B lymphopoiesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Involvement of chemokine receptors in breast cancer metastasis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Aiolos transcription factor controls cell death in T cells by regulating Bcl-2 expression and its cellular localization

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Aiolos regulates B cell activation and maturation to effector state

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

The adaptor protein Shc couples a class of integrins to the control of cell cycle progression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Disruption of epithelial cell-matrix interactions induces apoptosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Runx1 is essential at two stages of early murine B-cell development.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Deregulation of Aiolos expression in chronic lymphocytic leukemia is associated with epigenetic modifications

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

The Aiolos transcription factor is up-regulated in chronic lymphocytic leukemia

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4070880

Characterization of Early Stages of Human B Cell Development by Gene Expression Profiling

30 October 2018

1 reference

12 December 2020

Aberrant Ikaros, Aiolos, and Helios expression in Hodgkin and non-Hodgkin lymphoma

1 reference

12 December 2020

Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis

1 reference

12 December 2020

Small-cell lung cancer

1 reference

12 December 2020

10.1016/J.CCR.2014.03.020

Identifiers

DOI

1 reference

release_sx6vibj6sbff3bnk4is6ixd4hy

29 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/sx6vibj6sbff3bnk4is6ixd4hy

24 November 2022

mapped directly with Wikidata item

PMC publication ID

4070880

1 reference

29 July 2017

1 reference