Inhibition of human immunodeficiency virus type-1 by cdk inhibitors (Q33780297)

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29 January 2020

title

Inhibition of human immunodeficiency virus type-1 by cdk inhibitors (English)

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29 January 2020

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ChEBI release 2020-05-28

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29 January 2020

Fatah Kashanchi

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29 January 2020

Irene Guendel

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29 January 2020

Emmanuel T Agbottah

series ordinal

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29 January 2020

publication date

24 March 2010

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AIDS Research and Therapy

29 January 2020

published in

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29 January 2020

volume

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29 January 2020

issue

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29 January 2020

page(s)

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RNA polymerase II C-terminal heptarepeat domain Ser-7 phosphorylation is established in a mediator-dependent fashion

29 January 2020

cites work

1 reference

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation

4 July 2018

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Pharmacological cyclin-dependent kinase inhibitors inhibit replication of wild-type and drug-resistant strains of herpes simplex virus and human immunodeficiency virus type 1 by targeting cellular, not viral, proteins

4 July 2018

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Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy

4 July 2018

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GSK3 takes centre stage more than 20 years after its discovery

4 July 2018

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Missing links in GSK3 regulation.

4 July 2018

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Paullones are potent inhibitors of glycogen synthase kinase-3beta and cyclin-dependent kinase 5/p25.

4 July 2018

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CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA

4 July 2018

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Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription

4 July 2018

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Loss of G(1)/S checkpoint in human immunodeficiency virus type 1-infected cells is associated with a lack of cyclin-dependent kinase inhibitor p21/Waf1

4 July 2018

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P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA

4 July 2018

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TAK, an HIV Tat-associated kinase, is a member of the cyclin-dependent family of protein kinases and is induced by activation of peripheral blood lymphocytes and differentiation of promonocytic cell lines

4 July 2018

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Transcription elongation factor P-TEFb is required for HIV-1 Tat transactivation in vitro

4 July 2018

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The tumor suppressor protein p53 strongly alters human immunodeficiency virus type 1 replication

4 July 2018

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Regulation of human immunodeficiency virus infection: implications for pathogenesis

4 July 2018

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Cellular latency in human immunodeficiency virus-infected individuals with high CD4 levels can be detected by the presence of promoter-proximal transcripts

4 July 2018

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Lentivirus Tat proteins specifically associate with a cellular protein kinase, TAK, that hyperphosphorylates the carboxyl-terminal domain of the large subunit of RNA polymerase II: candidate for a Tat cofactor

4 July 2018

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Requirement for TFIIH kinase activity in transcription by RNA polymerase II

4 July 2018

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Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain

4 July 2018

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HIV-1 tat trans-activation requires the loop sequence within tar.

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Human immunodeficiency virus-encoded Tat activates glycogen synthase kinase-3beta to antagonize nuclear factor-kappaB survival pathway in neurons

21 January 2018

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Phase I clinical and pharmacokinetic study of flavopiridol in children with refractory solid tumors: a Children's Oncology Group Study

30 October 2018

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Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis.

30 October 2018

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Lithium ameliorates HIV-gp120-mediated neurotoxicity

30 October 2018

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A model of the G1 phase of the cell cycle incorporating cyclin E/cdk2 complex and retinoblastoma protein.

30 October 2018

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Phosphorylation causes a conformational change in the carboxyl-terminal domain of the mouse RNA polymerase II largest subunit

30 October 2018

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12 December 2020

Direct evidence that HIV-1 Tat stimulates RNA polymerase II carboxyl-terminal domain hyperphosphorylation during transcriptional elongation

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R-roscovitine (CYC202) alleviates renal cell proliferation in nephritis without aggravating podocyte injury

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Human general transcription factor IIH phosphorylates the C-terminal domain of RNA polymerase II

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12 December 2020

Identifiers

DOI

10.2217/THY.09.94

1 reference

PubMed publication ID

20334651

29 July 2017

10.1186/1742-6405-7-7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334651%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334651%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

PubMed publication ID

20334651

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20334651%20AND%20SRC:MED&resulttype=core&format=json