Contribution of p53 to metastasis (Q33776331)

29 July 2017

title

Contribution of p53 to metastasis (English)

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29 July 2017

David Piwnica-Worms

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29 July 2017

Emily Powell

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29 July 2017

Helen Piwnica-Worms

series ordinal

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29 July 2017

publication date

21 March 2014

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29 July 2017

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

405-414

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p53 in breast cancer subtypes and new insights into response to chemotherapy

29 July 2017

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4 July 2018

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4 July 2018

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Genome remodelling in a basal-like breast cancer metastasis and xenograft

4 July 2018

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Therapeutic targeting of p53 by small molecules.

4 July 2018

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Mutant p53 drives invasion by promoting integrin recycling

4 July 2018

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When mutants gain new powers: news from the mutant p53 field.

4 July 2018

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SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasis

4 July 2018

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XEDAR as a putative colorectal tumor suppressor that mediates p53-regulated anoikis pathway

4 July 2018

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p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug

4 July 2018

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A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

4 July 2018

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Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations

4 July 2018

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Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

p53 regulates FAK expression in human tumor cells

4 July 2018

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Crippling p53 activities via knock-in mutations in mouse models

4 July 2018

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Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility

4 July 2018

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Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

4 July 2018

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Restoration of p53 function leads to tumour regression in vivo

4 July 2018

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4 July 2018

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Gene expression patterns associated with p53 status in breast cancer.

4 July 2018

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Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: implications of p53 mutation or isoform expression on breast cancer cell invasion.

4 July 2018

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Wild-type p53 inhibits nuclear factor-kappaB-induced matrix metalloproteinase-9 promoter activation: implications for soft tissue sarcoma growth and metastasis

4 July 2018

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Proteomic identification of the wt-p53-regulated tumor cell secretome.

4 July 2018

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A global map of p53 transcription-factor binding sites in the human genome

4 July 2018

1 reference

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KAI1/CD82, a tumor metastasis suppressor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

Repression of the MSP/MST-1 gene contributes to the antiapoptotic gain of function of mutant p53

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

Genes that mediate breast cancer metastasis to lung

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

Transactivation of the EGR1 gene contributes to mutant p53 gain of function

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

A multigenic program mediating breast cancer metastasis to bone

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

Requirement of the p130CAS-Crk Coupling for Metastasis Suppressor KAI1/CD82-mediated Inhibition of Cell Migration

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

New functions for the matrix metalloproteinases in cancer progression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

Human mammary epithelial cells exhibit a differential p53-mediated response following exposure to ionizing radiation or UV light

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

Twist is a potential oncogene that inhibits apoptosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

The role of p53 in tumour suppression: lessons from mouse models

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

The expression of the KAI1 gene, a tumor metastasis suppressor, is directly activated by p53

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

Assay of matrix metalloproteinases types 1, 2, 3 and 9 in breast cancer.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

Transcriptional Activation by p53 of the Human Type IV Collagenase (Gelatinase A or Matrix Metalloproteinase 2) Promoter

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

The Li-Fraumeni syndrome: An inherited susceptibility to cancer

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

Receptor protein tyrosine kinase DDR is up-regulated by p53 protein

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

p53 modulation of anchorage independent growth and experimental metastasis.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

Disruption of epithelial cell-matrix interactions induces apoptosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

p53 mutations in matched primary and metastatic human tumors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

The p53 tumor suppressor gene inhibits angiogenesis by stimulating the production of thrombospondin.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

Differential regulation of plasminogen activator and inhibitor gene transcription by the tumor suppressor p53

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

Pathological prognostic factors in stage I (T1N0M0) and stage II (T1N1M0) breast carcinoma: a study of 644 patients with median follow-up of 18 years

4 July 2018

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Fate of recirculating B16 melanoma metastatic variant cells in parabiotic syngeneic recipients

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

p53 suppresses Src-induced podosome and rosette formation and cellular invasiveness through the upregulation of caldesmon

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

p53 suppresses the self-renewal of adult neural stem cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

High focal adhesion kinase expression in invasive breast carcinomas is associated with an aggressive phenotype

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

Blocking tumor growth, invasion, and metastasis by maspin in a syngeneic breast cancer model.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

Adenoviral-mediated gene therapy with Ad5CMVp53 and Ad5CMVp21 in combination with standard therapies in human breast cancer cell lines.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

In vitro and in vivo adherence of tumor cell variants correlated with tumor formation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063123

Apoptosis induced by denied adhesion to extracellular matrix (anoikis) in thyroid epithelial cells is p53 dependent but fails to correlate with modulation of p53 expression

30 October 2018

1 reference

12 December 2020

Matrix-metalloproteinases 1, 2, and 3 and their tissue inhibitors 1 and 2 in benign and malignant breast lesions: an in situ hybridization study

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12 December 2020

p53 regulates the expression of the tumor suppressor gene maspin

1 reference

12 December 2020

In vivo monitoring of the death rate of artificial murine pulmonary micrometastases

1 reference

12 December 2020

P53 expression in breast cancer

1 reference

12 December 2020

Down-regulation of fibronectin gene expression by the p53 tumor suppressor protein

1 reference

12 December 2020

Strong correlation of basement membrane degradation with p53 inactivation and/or MDM2 overexpression in superficial urothelial carcinomas

1 reference

12 December 2020

p53 down-regulates human matrix metalloproteinase-1 (Collagenase-1) gene expression

1 reference

12 December 2020

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

12 December 2020

10.1158/2159-8290.CD-13-0136

Identifiers

DOI

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29 July 2017

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29 July 2017

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