EGFRvIII-targeted immunotoxin induces antitumor immunity that is inhibited in the absence of CD4+ and CD8+ T cells (Q33758468)

29 July 2017

title

EGFRvIII-targeted immunotoxin induces antitumor immunity that is inhibited in the absence of CD4+ and CD8+ T cells (English)

1 reference

29 July 2017

Darell D Bigner

1 reference

29 July 2017

Hidenobu Ochiai

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29 July 2017

Gary E Archer

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29 July 2017

James E Herndon

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29 July 2017

Chien-Tsun Kuan

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29 July 2017

Duane A Mitchell

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29 July 2017

Ira H Pastan

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29 July 2017

John H Sampson

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29 July 2017

publication date

19 July 2007

1 reference

Cancer Immunology, Immunotherapy

29 July 2017

published in

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

115-121

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Efficient cross-priming of tumor antigen-specific T cells by dendritic cells sensitized with diverse anti-MICA opsonized tumor cells

29 July 2017

cites work

1 reference

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Sustained radiographic and clinical response in patient with bifrontal recurrent glioblastoma multiforme with intracerebral infusion of the recombinant targeted toxin TP-38: case study

14 July 2018

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TP-3 immunotoxins improve antitumor activity in mice with osteosarcoma.

14 July 2018

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Recombinant immunotoxins for treating cancer

14 July 2018

1 reference

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In vitro and in vivo cytotoxic activities of recombinant immunotoxin 8H9(Fv)-PE38 against breast cancer, osteosarcoma, and neuroblastoma

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846815

Recombinant immunotoxins in the treatment of cancer

14 July 2018

1 reference

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Mini‐review: Regulation of cytotoxic T lymphocyte responses by dendritic cells: peaceful coexistence of cross‐priming and direct priming?

14 July 2018

1 reference

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Immunotoxins containing Pseudomonas exotoxin A: a short history

14 July 2018

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The danger model: a renewed sense of self

14 July 2018

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Cross-presentation in viral immunity and self-tolerance.

14 July 2018

1 reference

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Efficacy of the anti-CD22 recombinant immunotoxin BL22 in chemotherapy-resistant hairy-cell leukemia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846815

Dendritic cells are sufficient to cross-present self-antigens to CD8 T cells in vivo

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846815

Increased binding affinity enhances targeting of glioma xenografts by EGFRvIII-specific scFv

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846815

Unarmed, tumor-specific monoclonal antibody effectively treats brain tumors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846815

125I-labeled anti-epidermal growth factor receptor-vIII single-chain Fv exhibits specific and high-level targeting of glioma xenografts.

14 July 2018

1 reference

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Immunotoxins that target an oncogenic mutant epidermal growth factor receptor expressed in human tumors.

14 July 2018

1 reference

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Characterization of a Spontaneous Murine Astrocytoma and Abrogation of Its Tumorigenicity by Cytokine Secretion

14 July 2018

1 reference

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Recombinant immunotoxins specific for a mutant epidermal growth factor receptor: targeting with a single chain antibody variable domain isolated by phage display

14 July 2018

1 reference

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Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates CD8+ cell-mediated immunity against tumors located in the "immunologically privileged" central nervous system

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846815

Immunotoxins and central nervous system neoplasia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846815

Neuroradiographic changes following convection-enhanced delivery of the recombinant cytotoxin interleukin 13-PE38QQR for recurrent malignant glioma

14 July 2018

1 reference

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Long term survival in a patient with recurrent malignant glioma treated with intratumoral infusion of an IL4-targeted toxin (NBI-3001).

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846815

Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malig

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846815

Mutants of immunotoxin anti-Tac(dsFv)-PE38 with variable number of lysine residues as candidates for site-specific chemical modification. 1. Properties of mutant molecules

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846815

Regional treatment of epidermal growth factor receptor vIII-expressing neoplastic meningitis with a single-chain immunotoxin, MR-1.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846815

Immunotoxins in cancer therapy

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17634939

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Induction of caspase-dependent programmed cell death in B-cell chronic lymphocytic leukemia by anti-CD22 immunotoxins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17634939

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Abrogation of head and neck squamous cell carcinoma growth by epidermal growth factor receptor ligand fused to pseudomonas exotoxin transforming growth factor alpha-PE38

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17634939

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00262-007-0363-7

1 reference

Dimensions Publication ID

29 July 2017

0 references

1 reference

29 July 2017

1 reference